Trabajo Académico

• ORCID
• Google académico
• ResearchGate
• Scopus

Cuerpo académico

• Bioenergética y envejecimiento celular

Incidencia en los ODS ONU

Intereses de investigación

• Envejecimiento
• Senescencia celular
• Estrés oxidante
• Bioenergética
• Enfermedades crónicodegenerativas

Semblanza

La Doctora Mina Konigsberg Fainstein nació en la Ciudad de México, antes Distrito Federal. Realizó la licenciatura y la maestría en Biología Experimental en la Universidad Autónoma Metropolitana y el doctorado en ciencias biológicas en esa misma casa de estudio donde ahora es Profesora Titular C y Responsable del Laboratorio de Bioenergética y Envejecimiento Celular del Departamento Ciencias de la Salud.

Realizó una estancia sabática en el Barshop Institute for Aging and Longevity studies. Health Science Center. University of Texas, San Antonio, con una beca Fulbright y del CONACyT. Ha publicado varios artículos científicos y de divulgación, y ha dirigido tesis de alumnos de licenciatura y posgrado.

Es miembro de la Society for Redox Biology And Medicine, American Aging Association, Academia Mexicana de las Ciencias y del Sistema Nacional de investigadores nivel III.

Información proporcionada por el personal académico

Intereses de investigación

• Envejecimiento
• Senescencia celular
• Estrés oxidante
• Bioenergética
• Enfermedades crónicodegenerativas

Trabajo Académico

En las páginas siguientes puede consultar el trabajo de investigación:

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• ResearchGate

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• Scopus

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• ORCID

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Cuerpo académico

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• Bioenergética y envejecimiento celular

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Algunos ejemplos de publicaciones

Seleccione la referencia bibliografica para consultar cada publicación:

Open Access	Referencias	ODS ONU
OA	Saldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,9
	Pedraza-Vázquez, G., Mena-Montes, B., Hernández-Álvarez, D. and 6 more (...) (2023).A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation. Archives of Gerontology and Geriatrics,105	\| 3 \|
OA	Silva-Palacios, A., Colín-González, A.L., López-Cervantes, S.P. and 4 more (...) (2023).Corrigendum to “Tert-buthylhydroquinone pre-conditioning exerts dual effects in old rats exposed to 3-nitropropionic acid” [Redox Biol. 12 (2017) 610–624, (S2213231717301295), (10.1016/j.redox.2017.03.029)]. Redox Biology,65
OA	Salas-Venegas, V., Santín-Márquez, R., Ramírez-Carreto, R.J. and 6 more (...) (2023).Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats. Frontiers in Aging Neuroscience,15	\| 3 \|
	López-Cervantes, S.P., Sánchez, N.S., Calahorra, M. and 10 more (...) (2022).Moderate exercise combined with metformin-treatment improves mitochondrial bioenergetics of the quadriceps muscle of old female Wistar rats. Archives of Gerontology and Geriatrics,102
	Santín-Márquez, R., Hernández-Arciga, U., Salas-Venegas, V. and 7 more (...) (2022).Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals. Biogerontology,23(5) 587-613
	Olascoaga-Del Angel, K.S., Gutierrez, H., Königsberg, M. and 2 more (...) (2022).Exploring the fuzzy border between senolytics and senomorphics with chemoinformatics and systems pharmacology. Biogerontology,23(4) 453-471
OA	Luna-López, A., Flores-González, G.A., Rivera-Ruz, I.A. and 4 more (...) (2022).Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes. Dose-Response,20(3)
OA	Salas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,16	\| 3 \|
	López-Teros, M., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2022).Contribution of senescent and reactive astrocytes on central nervous system inflammaging. Biogerontology,23(1) 21-33
	López-Trinidad, B.P., Vigueras-Villaseñor, R.M., Konigsberg, M. and 5 more (...) (2021).Alterations in epididymal sperm maturation caused by ageing. Reproduction, Fertility and Development,33(18) 855-864
OA	Toledo-Perez, R., Lopez-Cervantes, S.P., Hernandez-Alvarez, D. and 6 more (...) (2021).Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle-Aged Wistar Female Rats. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
OA	Mena-Montes, B., Hernández-Álvarez, D., Pedraza-Vázquez, G. and 9 more (...) (2021).Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF-11. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
OA	Morales-Rosales, S.L., Santín-Márquez, R., Posadas-Rodriguez, P. and 12 more (...) (2021).Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons. Frontiers in Aging Neuroscience,13
OA	Santín-Márquez, R., Ramírez-Cordero, B., Toledo-Pérez, R. and 12 more (...) (2021).Sensory and memory processing in old female and male Wistar rat brain, and its relationship with the cortical and hippocampal redox state. GeroScience,43(4) 1899-1920
OA	Hernández-Mercado, E., Prieto-Chávez, J.L., Arriaga-Pizano, L.A. and 4 more (...) (2021).Increased CD47 and MHC class I inhibitory signals expression in senescent cd1 primary mouse lung fibroblasts. International Journal of Molecular Sciences,22(19)	\| 3 \|
	Hernández-Arciga, U., Hernández-Álvarez, D., López-Cervantes, S.P. and 4 more (...) (2020).Effect of long-term moderate-exercise combined with metformin-treatment on antioxidant enzymes activity and expression in the gastrocnemius of old female Wistar rats. Biogerontology,21(6) 787-805
OA	Hernández-Arciga, U., Herrera, L.G.M., Königsberg, M. and 3 more (...) (2020).Synergetic effects of immune challenge and stress depress cortisol, inflammatory response and antioxidant activity in fish-eating Myotis. Journal of Experimental Biology,223(24)	\| 14 \|
	Morales-Rosales, S.L., Rivero-Segura, N.A., Königsberg, M. (2020).Mitochondrial function in aging. Clinical Genetics and Genomics of Aging,65-85
	Parra-Cid, C., Orozco-Castillo, E., García-López, J. and 7 more (...) (2020).Early expression of neuronal dopaminergic markers in a Parkinson’s disease model in rats implanted with enteric stem cells (ENSCs). CNS and Neurological Disorders - Drug Targets,19(2) 148-162
OA	Posadas-Rodríguez, P., Posadas-Rodríguez, N.E., González-Puertos, V.Y. and 6 more (...) (2020).TBHQ Induces a Hormetic Response That Protects L6 Myoblasts against the Toxic Effect of Palmitate. Oxidative Medicine and Cellular Longevity,2020	\| 3 \|
OA	Medina-Flores, F., Hurtado-Alvarado, G., Contis-Montes de Oca, A. and 4 more (...) (2020).Sleep loss disrupts pericyte-brain endothelial cell interactions impairing blood-brain barrier function. Brain, Behavior, and Immunity,89118-132
OA	Alarcón-Aguilar, A., Luna-López, A., López-Diazguerrero, N.E. and 1 more (...) (2019).Correction to: The Effect of MPP+ on the Viability of Primary Cortical Astrocytes Isolated from Female and Male Wistar Rats of Different Ages (Cellular and Molecular Neurobiology, (2019), 39, 2, (321-328), 10.1007/s10571-018-0643-0). Cellular and Molecular Neurobiology,39(2)
OA	Santín-Márquez, R., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2019).Sulforaphane - role in aging and neurodegeneration. GeroScience,41(5) 655-670
	Alarcón-Aguilar, A., Luna-López, A., López-Diazguerrero, N.E. and 1 more (...) (2019).The Effect of MPP+ on the Viability of Primary Cortical Astrocytes Isolated from Female and Male Wistar Rats of Different Ages. Cellular and Molecular Neurobiology,39(2) 321-328
	Silva-Palacios, A., Ostolga-Chavarría, M., Sánchez-Garibay, C. and 7 more (...) (2019).Sulforaphane protects from myocardial ischemia-reperfusion damage through the balanced activation of Nrf2/AhR. Free Radical Biology and Medicine,143331-340	\| 3 \|
	Gómez-Linton, D.R., Alavez, S., Alarcón-Aguilar, A. and 3 more (...) (2019).Some naturally occurring compounds that increase longevity and stress resistance in model organisms of aging. Biogerontology,20(5) 583-603
OA	Hernández-Álvarez, D., Mena-Montes, B., Toledo-Pérez, R. and 15 more (...) (2019).Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats. Oxidative Medicine and Cellular Longevity,2019
OA	Moreno-Blas, D., Gorostieta-Salas, E., Pommer-Alba, A. and 6 more (...) (2019).Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging,11(16) 6175-6198
OA	Alarcón-Aguilar, A., Maycotte-González, P., Cortés-Hernández, P. and 2 more (...) (2019).Mitochondrial dynamics in neurodegenerative diseases. Gaceta Medica de Mexico,155(3) 276-283
OA	Hernández Bautista, R.J., Mahmoud, A.M., Königsberg, M. and 1 more (...) (2019).Obesity: Pathophysiology, monosodium glutamate-induced model and anti-obesity medicinal plants. Biomedicine and Pharmacotherapy,111503-516	\| 3 \|
	Aguilera-Portillo, G., Rangel-López, E., Villeda-Hernández, J. and 8 more (...) (2019).The Pharmacological Inhibition of Fatty Acid Amide Hydrolase Prevents Excitotoxic Damage in the Rat Striatum: Possible Involvement of CB1 Receptors Regulation. Molecular Neurobiology,56(2) 844-856
	Ibáñez-Contreras, A., Hernández-Arciga, U., Poblano, A. and 7 more (...) (2018).Electrical activity of sensory pathways in female and male geriatric Rhesus monkeys (Macaca mulatta), and its relation to oxidative stress. Experimental Gerontology,10180-94
	Maciel-Barón, L.Á., Morales-Rosales, S.L., Silva-Palacios, A. and 6 more (...) (2018).The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on neuronal mitochondrial potential. Biogerontology,19(5) 415-433
OA	Gavia-García, G., Rosas-Trejo, M.D.L.Á., García-Mendoza, E. and 5 more (...) (2018).t-BHQ Protects Against Oxidative Damage and Maintains the Antioxidant Response in Malnourished Rats. Dose-Response,16(3)	\| 2 \|
OA	Hernández-Arciga, U., Herrera M, L.G., Ibáñez-Contreras, A. and 3 more (...) (2018).Baseline and post-stress seasonal changes in immunocompetence and redox state maintenance in the fishing bat Myotis vivesi. PLoS ONE,13(1)
	MacIel-Barón, L.A., Moreno-Blas, D., Morales-Rosales, S.L. and 5 more (...) (2018).Cellular Senescence, Neurological Function, and Redox State. Antioxidants and Redox Signaling,28(18) 1704-1723
	Silva-Palacios, A., Ostolga-Chavarría, M., Zazueta, C. and 1 more (...) (2018).Nrf2: Molecular and epigenetic regulation during aging. Ageing Research Reviews,4731-40
OA	Rodríguez-Barrera, R., Flores-Romero, A., Fernández-Presas, A.M. and 8 more (...) (2017).Immunization with neural derived peptides plus scar removal induces a permissive microenvironment, and improves locomotor recovery after chronic spinal cord injury. BMC Neuroscience,18(1)
OA	Silva-Palacios, A., Colín-González, A.L., López-Cervantes, S.P. and 4 more (...) (2017).Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid. Redox Biology,12610-624
	Ibáñez-Contreras, A., Braulio Hernández-Godínez, Mendoza-Cuevas, G. and 2 more (...) (2017).The effect of oxidative stress on brain electrical activity and its repercussions on sensory organization in geriatric rhesus monkeys in captivity. Evoked Potentials and Electrical Stimulation: Clinical Roles, Challenges and Emerging Research,95-128
	Silva-Palacios, A., Ostolga-Chavarría, M., Buelna-Chontal, M. and 7 more (...) (2017).3-NP-induced Huntington's-like disease impairs Nrf2 activation without loss of cardiac function in aged rats. Experimental Gerontology,9689-98	\| 3 \|
	Maya-López, M., Colín-González, A.L., Aguilera, G. and 13 more (...) (2017).Neuroprotective effect of WIN55,212-2 against 3-nitropropionic acid-induced toxicity in the rat brain: Involvement of CB1 and NMDA receptors. American Journal of Translational Research,9(2) 261-274
	Barajas-Gómez, B.A., Rosas-Carrasco, O., Morales-Rosales, S.L. and 8 more (...) (2017).Relationship of inflammatory profile of elderly patients serum and senescence-associated secretory phenotype with human breast cancer cells proliferation: Role of IL6/IL8 ratio. Cytokine,9113-29	\| 3 \|
	Silva-Palacios, A., Königsberg, M., Zazueta, C. (2016).Nrf2 signaling and redox homeostasis in the aging heart: A potential target to prevent cardiovascular diseases?. Ageing Research Reviews,2681-95	\| 3 \|
	Triana-Martínez, F., Pedraza-Vázquez, G., Maciel-Barón, L.A. and 1 more (...) (2016).Reflections on the role of senescence during development and aging. Archives of Biochemistry and Biophysics,59840-49	\| 3 \|
OA	Maciel-Barón, L.A., Morales-Rosales, S.L., Aquino-Cruz, A.A. and 7 more (...) (2016).Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli. Age,38(1) 1-14
	López-Vidal, O., Camejo, D., Rivera-Cabrera, F. and 7 more (...) (2016).Mitochondrial ascorbate-glutathione cycle and proteomic analysis of carbonylated proteins during tomato (Solanum lycopersicum) fruit ripening. Food Chemistry,1941064-1072
	Ibáñez-Contreras, A., Poblano, A., Arteaga-Silva, M. and 4 more (...) (2016).Visual, auditive and somatosensory pathways alterations in geriatric rhesus monkeys (Macaca mulatta). Journal of Medical Primatology,45(2) 92-102
	Gavia-García, G., González-Martínez, H., Miliar-García, Á. and 6 more (...) (2015).Oxidative damage and antioxidant defense in thymus of malnourished lactating rats. Nutrition,31(11-12) 1408-1415	\| 2 \|
	Trejo-Vargas, A., Hernández-Mercado, E., Ordóñez-Razo, R.M. and 5 more (...) (2015).Bik subcellular localization in response to oxidative stress induced by chemotherapy, in Two different breast cancer cell lines and a Non-tumorigenic epithelial cell line. Journal of Applied Toxicology,35(11) 1262-1270	\| 3 \|
OA	Osorio-Rico, L., Villeda-Hernández, J., Santamaría, A. and 2 more (...) (2015).The N-Methyl-d-Aspartate Receptor Antagonist MK-801 Prevents Thallium-Induced Behavioral and Biochemical Alterations in the Rat Brain. International Journal of Toxicology,34(6) 505-513
	González-Puertos, V.Y., Maciel-Barón, L.Á., Barajas-Gómez, B.A. and 2 more (...) (2015).Participation of the senescent-associated secretory phenotype in cancer development, aging and age-related diseases. Gaceta Medica de Mexico,151(4) 491-500	\| 3 \|
	Triana-Martínez, F., López-Diazguerrero, N.E., Maciel-Barón, L.A. and 7 more (...) (2014).Cell proliferation arrest and redox state status as part of different stages during senescence establishment in mouse fibroblasts. Biogerontology,15(2) 165-176
OA	Luna–López, A., González-Puertos, V.Y., López-Diazguerrero, N.E. and 1 more (...) (2014).New considerations on hormetic response against oxidative stress. Journal of Cell Communication and Signaling,8(4) 323-331	\| 3 \|
	Colín-González, A.L., Luna-López, A., Königsberg, M. and 3 more (...) (2014).Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway. Neuroscience,260130-139
OA	Hernández-Bautista, R.J., Alarcón-Aguilar, F.J., Escobar-Villanueva, M.D.C. and 4 more (...) (2014).Biochemical alterations during the obese-aging process in female and male monosodium glutamate (MSG)-treated mice. International Journal of Molecular Sciences,15(7) 11473-11494	\| 3 \|
	Ibáñez-Contreras, A., Poblano, A., Hernández-Godínez, B. and 4 more (...) (2014).The use of non-human primates as bio-models for aging brain studies: Interventional role of oxidative stress in demyelization processes. Monkeys: Brain Development, Social & Hormonal Mechanisms and Zoonotic Diseases,35-50
	Alarcón-Aguilar, A., González-Puertos, V.Y., Luna-López, A. and 4 more (...) (2014).Comparing the effects of two neurotoxins in cortical astrocytes obtained from rats of different ages: Involvement of oxidative damage. Journal of Applied Toxicology,34(2) 127-138
	Alarcón-Aguilar, A., Luna-López, A., Ventura-Gallegos, J.L. and 6 more (...) (2014).Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment. Neurobiology of Aging,35(8) 1901-1912
OA	Jiménez-Salazar, J.E., Posadas-Rodríguez, P., Lazzarini-Lechuga, R.C. and 6 more (...) (2014).Membrane-Initiated Estradiol Signaling of Epithelial-Mesenchymal Transition-Associated Mechanisms Through Regulation of Tight Junctions in Human Breast Cancer Cells. Hormones and Cancer,5(3) 161-173	\| 3 \|
OA	Lerner, C., Bitto, A., Pulliam, D. and 5 more (...) (2013).Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell,12(6) 966-977
OA	Rodríguez-Barrera, R., Fernández-Presas, A.M., García, E. and 9 more (...) (2013).Immunization with a neural-derived peptide protects the spinal cord from apoptosis after traumatic injury. BioMed Research International,2013	\| 3 \|
	Luna-López, A., González-Puertos, V.Y., Romero-Ontiveros, J. and 4 more (...) (2013).A noncanonical NF-κB pathway through the p50 subunit regulates Bcl-2 overexpression during an oxidative-conditioning hormesis response. Free Radical Biology and Medicine,6341-50
OA	Konigsberg, M., Pérez, V.I., Ríos, C. and 4 more (...) (2013).Effect of oxygen tension on bioenergetics and proteostasis in young and old myoblast precursor cells. Redox Biology,1(1) 475-482
	López-Diazguerrero, N.E., González Puertos, V.Y., Hernández-Bautista, R.J. and 3 more (...) (2013).Hormesis: What does not kill, strengthens. Gaceta Medica de Mexico,149(4) 438-447	\| 3 \|
	Flores-López, L.A., Díaz-Flores, M., García-Macedo, R. and 6 more (...) (2013).High glucose induces mitochondrial p53 phosphorylation by p38 MAPK in pancreatic RINm5F cells. Molecular Biology Reports,40(8) 4947-4958	\| 3 \|

Cursos impartidos

No.	Trim.	Nombre UEA	Nivel
1	23O	Seminario IV	Posgrado
2	23O	Trabajo de Investigación IV	Posgrado
3	23O	Biología Celular	Posgrado
4	23O	Temas Selectos de Biología Experimental I	Posgrado
5	23O	Temas Selectos de Biología Experimental I	Posgrado
6	23O	Trabajo Experimental I	Posgrado
7	23O	Trabajo de Investigación IV	Posgrado
8	23O	Trabajo de Investigación VI	Posgrado
9	23O	Trabajo de Investigación VIII	Posgrado
10	23O	Seminario de Escritura de Tesis I	Posgrado
11	23O	Epigenética	Licenciatura
12	23O	Proyecto de Investigación I	Licenciatura
13	23P	Seminario III	Posgrado
14	23P	Trabajo de Investigación III	Posgrado
15	23P	Trabajo de Investigación III	Posgrado
16	23P	Trabajo de Investigación V	Posgrado
17	23P	Trabajo de Investigación VII	Posgrado
18	23P	Trabajo de Investigación IX	Posgrado
19	23P	Seminario de Escritura de Tesis III	Posgrado
20	23P	Seminario de Escritura de Tesis III	Posgrado
21	23P	Respuesta de los Organismos al Estrés	Licenciatura
22	23I	Bioquímica y Biología Molecular I	Posgrado
23	23I	Trabajo de Investigación I	Posgrado
24	23I	Trabajo de Investigación II	Posgrado
25	23I	Trabajo de Investigación IV	Posgrado
26	23I	Trabajo de Investigación VI	Posgrado
27	23I	Trabajo de Investigación VIII	Posgrado
28	23I	Seminario de Escritura de Tesis II	Posgrado
29	23I	Seminario de Escritura de Tesis II	Posgrado
30	23I	Seminario II	Posgrado
31	23I	Trabajo de Investigación II	Posgrado
32	23I	Respuesta de los Organismos al Estrés	Licenciatura
33	22O	Seminario I	Posgrado
34	22O	Trabajo de Investigación I	Posgrado
35	22O	Biología Celular	Posgrado
36	22O	Trabajo de Investigación I	Posgrado
37	22O	Trabajo de Investigación III	Posgrado
38	22O	Trabajo de Investigación V	Posgrado
39	22O	Trabajo de Investigación VII	Posgrado
40	22O	Seminario de Escritura de Tesis I	Posgrado
41	22O	Seminario de Escritura de Tesis I	Posgrado
42	22O	Seminario de Escritura de Tesis III	Posgrado
43	22O	Proyecto de Investigación III	Licenciatura
44	22O	Epigenética	Licenciatura
45	22P	Temas Selectos de Biología Experimental I	Posgrado
46	22P	Trabajo de Investigación II	Posgrado
47	22P	Trabajo de Investigación IV	Posgrado
48	22P	Trabajo de Investigación VI	Posgrado
49	22P	Trabajo de Investigación IX	Posgrado
50	22P	Trabajo de Investigación IX	Posgrado
51	22P	Seminario de Escritura de Tesis II	Posgrado
52	22P	Seminario de Escritura de Tesis III	Posgrado
53	22P	Respuesta de los Organismos al Estrés	Licenciatura
54	22P	Proyecto de Investigación II	Licenciatura
55	22P	Proyecto de Investigación III	Licenciatura
56	22I	Trabajo Experimental III	Posgrado
57	22I	Trabajo de Investigación I	Posgrado
58	22I	Trabajo de Investigación III	Posgrado
59	22I	Trabajo de Investigación V	Posgrado
60	22I	Trabajo de Investigación VIII	Posgrado

Información proporcionada por la Dirección de Sistemas Escolares

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