Academic Work

• ORCID
• Google scholar
• ResearchGate
• Scopus

Sustainable Development Goals

Research interests

• Aging
• Cellular senescence
• Oxidative stress
• Bioenergetics
• Chronic and degenerative diseases

Profile

Professor Mina Konigsberg Fainstein was born in Mexico City. She received her B.S. and M.S. degrees in Experimental Biology from the Universidad Autónoma Metropolitana (UAM) and her Ph.D. in Biological Sciences from the same university where she is now Professor and Head of the Bioenergetics and Cellular Aging Laboratory of the Health Sciences Department.

She completed a sabbatical stay at the Barshop Institute for Aging and Longevity studies. Health Science Center. University of Texas, San Antonio, with a Fulbright and CONACyT grant. She has published several scientific and popular articles and has supervised theses of undergraduate and graduate students.

She is a member of the Society for Redox Biology And Medicine, American Aging Association, Academia Mexicana de las Ciencias and the National System of Researchers, level III.

Information provided by the academic staff

Research interests

• Aging
• Cellular senescence
• Oxidative stress
• Bioenergetics
• Chronic and degenerative diseases

Academic Work

On the following pages you can consult the research work:

• Google scholar

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• ResearchGate

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• Scopus

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• ORCID

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Some examples of publications

Select the bibliographic reference to consult each publication:

Open Access	References	UN SDGs
OA	Ávila-Galicia, K.E., Alarcón-Aguilar, A., Soto-Reyes, E. and 1 more (...) (2026).Epigenetic remodeling induced by fatty acids: Chromatin modifications and cellular senescence during lipid overload. Ageing Research Reviews,118	\| 3 \|
	Silva-Palacios, A., Zúñiga-Muñoz, A.M., Soria-Castro, E. and 11 more (...) (2025).Cardioprotective effect of senotherapy in chronically obese middle-aged female rats may be mediated by a MERCSs/Nrf2 interaction. Journal of Nutritional Biochemistry,142	\| 3 \|
OA	Flores-Torres, R.P., Salas-Venegas, V., Santín-Márquez, R. and 10 more (...) (2025).“Senotherapy as a multitarget intervention in chronic obesity: Modulation of senescence, neuroinflammation, dysbiosis, and synaptic integrity in middle-aged female Wistar rats”. Experimental Neurology,392	\| 3 \|
OA	López-Teros, M., Ávila-Galicia, K.E., Librado-Osorio, R. and 7 more (...) (2025).Palmitate-Induced Primary Rat Senescent Astrocytes Exhibit Higher Inflammatory Activity and a Distinct Transcriptomic Profile Compared to Reactive Astrocytes. Journal of Neurochemistry,169(7)
OA	Avilez-Avilez, J.J., García-Aviles, J.E., Ramírez-Carreto, R.J. and 6 more (...) (2025).Progressive Blood–Brain Barrier Disruption in Sleep-Restricted Young Mice: Cellular Senescence and Neuroinflammation Crosstalk. Neurochemical Research,50(5)
OA	Santín-Márquez, R., Salas-Venegas, V., Garcia-Álvarez, J.A. and 5 more (...) (2025).Sex differences in middle-aged and old Wistar rats in response to long-term sulforaphane treatment for prevention of neuroinflammation, cognitive decline and brain senescence. Biogerontology,26(3)
OA	Olascoaga, S., Konigsberg, M., Espinal-Enríquez, J. and 4 more (...) (2025).Transcriptomic signatures and network-based methods uncover new senescent cell anti-apoptotic pathways and senolytics. FEBS Journal,292(8) 1950-1971	\| 3 \|
	López-Teros, M., Alarcón-Aguilar, A., Castillo-Aragón, A. and 2 more (...) (2024).Cytokine profiling in senescent and reactive astrocytes: A systematic review. Neurobiology of Aging,13828-35
OA	Nieto, M., Konigsberg, M., Silva-Palacios, A. (2024).Correction to: Quercetin and dasatinib, two powerful senolytics in age-related cardiovascular disease (Biogerontology, (2024), 25, 1, (71-82), 10.1007/s10522-023-10068-5). Biogerontology,25(4)	\| 3 \|
OA	Olascoaga, S., Castañeda-Sánchez, J.I., Königsberg, M. and 2 more (...) (2024).Oxidative stress-induced gene expression changes in prostate epithelial cells in vitro reveal a robust signature of normal prostatic senescence and aging. Biogerontology,25(6) 1145-1169
OA	Saldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,9	\| 4 \| 10 \|
OA	López-Cervantes, S.P., Toledo-Pérez, R., De Lira-Sánchez, J.A. and 6 more (...) (2024).Sedentary Lifestyles and a Hypercaloric Diets During Middle Age, are Binomial Conducive to Fatal Progression, That is Counteracted by the Hormetic Treatment of Exercise, Metformin, and Tert-Butyl Hydroquinone: An Analysis of Female Middle-Aged Rat Liver Mitochondria. Dose-Response,22(4)	\| 3 \|
OA	Salas-Venegas, V., Santín-Márquez, R., Ramírez-Carreto, R.J. and 6 more (...) (2023).Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats. Frontiers in Aging Neuroscience,15	\| 3 \|
	Pedraza-Vázquez, G., Mena-Montes, B., Hernández-Álvarez, D. and 6 more (...) (2023).A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation. Archives of Gerontology and Geriatrics,105	\| 3 \|
OA	Silva-Palacios, A., Colín-González, A.L., López-Cervantes, S.P. and 4 more (...) (2023).Corrigendum to “Tert-buthylhydroquinone pre-conditioning exerts dual effects in old rats exposed to 3-nitropropionic acid” [Redox Biol. 12 (2017) 610–624, (S2213231717301295), (10.1016/j.redox.2017.03.029)]. Redox Biology,65
OA	Salas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,16	\| 3 \|
	Olascoaga-Del Angel, K.S., Gutierrez, H., Königsberg, M. and 2 more (...) (2022).Exploring the fuzzy border between senolytics and senomorphics with chemoinformatics and systems pharmacology. Biogerontology,23(4) 453-471
	López-Teros, M., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2022).Contribution of senescent and reactive astrocytes on central nervous system inflammaging. Biogerontology,23(1) 21-33
OA	Luna-López, A., Flores-González, G.A., Rivera-Ruz, I.A. and 4 more (...) (2022).Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes. Dose-Response,20(3)
	Santín-Márquez, R., Hernández-Arciga, U., Salas-Venegas, V. and 7 more (...) (2022).Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals. Biogerontology,23(5) 587-613
	López-Cervantes, S.P., Sánchez, N.S., Calahorra, M. and 10 more (...) (2022).Moderate exercise combined with metformin-treatment improves mitochondrial bioenergetics of the quadriceps muscle of old female Wistar rats. Archives of Gerontology and Geriatrics,102
OA	Morales-Rosales, S.L., Santín-Márquez, R., Posadas-Rodriguez, P. and 12 more (...) (2021).Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons. Frontiers in Aging Neuroscience,13
OA	Santín-Márquez, R., Ramírez-Cordero, B., Toledo-Pérez, R. and 12 more (...) (2021).Sensory and memory processing in old female and male Wistar rat brain, and its relationship with the cortical and hippocampal redox state. GeroScience,43(4) 1899-1920
OA	Mena-Montes, B., Hernández-Álvarez, D., Pedraza-Vázquez, G. and 9 more (...) (2021).Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF-11. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
OA	Toledo-Perez, R., Lopez-Cervantes, S.P., Hernandez-Alvarez, D. and 6 more (...) (2021).Metformin and tBHQ Treatment Combined with an Exercise Regime Prevents Osteosarcopenic Obesity in Middle-Aged Wistar Female Rats. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
	López-Trinidad, B.P., Vigueras-Villaseñor, R.M., Konigsberg, M. and 5 more (...) (2021).Alterations in epididymal sperm maturation caused by ageing. Reproduction, Fertility and Development,33(18) 855-864
OA	Hernández-Mercado, E., Prieto-Chávez, J.L., Arriaga-Pizano, L.A. and 4 more (...) (2021).Increased CD47 and MHC class I inhibitory signals expression in senescent cd1 primary mouse lung fibroblasts. International Journal of Molecular Sciences,22(19)
	Parra-Cid, C., Orozco-Castillo, E., García-López, J. and 7 more (...) (2020).Early expression of neuronal dopaminergic markers in a Parkinson’s disease model in rats implanted with enteric stem cells (ENSCs). CNS and Neurological Disorders - Drug Targets,19(2) 148-162	\| 3 \|
OA	Posadas-Rodríguez, P., Posadas-Rodríguez, N.E., González-Puertos, V.Y. and 6 more (...) (2020).TBHQ Induces a Hormetic Response That Protects L6 Myoblasts against the Toxic Effect of Palmitate. Oxidative Medicine and Cellular Longevity,2020	\| 3 \|
OA	Medina-Flores, F., Hurtado-Alvarado, G., Contis-Montes de Oca, A. and 4 more (...) (2020).Sleep loss disrupts pericyte-brain endothelial cell interactions impairing blood-brain barrier function. Brain, Behavior, and Immunity,89118-132
	Hernández-Arciga, U., Hernández-Álvarez, D., López-Cervantes, S.P. and 4 more (...) (2020).Effect of long-term moderate-exercise combined with metformin-treatment on antioxidant enzymes activity and expression in the gastrocnemius of old female Wistar rats. Biogerontology,21(6) 787-805
OA	Hernández-Arciga, U., Herrera, L.G.M., Königsberg, M. and 3 more (...) (2020).Synergetic effects of immune challenge and stress depress cortisol, inflammatory response and antioxidant activity in fish-eating Myotis. Journal of Experimental Biology,223(24)	\| 14 \|
	Morales-Rosales, S.L., Rivero-Segura, N.A., Königsberg, M. (2020).Mitochondrial function in aging. Clinical Genetics and Genomics of Aging,65-85

Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.	Trim.	Course Name	Level
1	26I	Respuesta de los Organismos al Estrés	Licenciatura
2	26I	Seminario de Escritura de Tesis II	Posgrado
3	26I	Temas Selectos de Biología Experimental II	Posgrado
4	26I	Trabajo de Investigación V	Posgrado
5	26I	Trabajo de Redacción de Tesis II	Posgrado
6	26I	Trabajo Experimental II	Posgrado
7	26I	Trabajo Experimental II	Posgrado
8	26I	Trabajo Experimental II	Posgrado
9	26I	Trabajo Experimental II	Posgrado
10	26I	Bioquímica y Biología Molecular I	Posgrado
11	25O	Biología Celular	Posgrado
12	25O	Epigenética	Licenciatura
13	25O	Proyecto de Investigación II	Licenciatura
14	25O	Seminario de Escritura de Tesis I	Posgrado
15	25O	Seminario de Escritura de Tesis III	Posgrado
16	25O	Temas Selectos de Biología Experimental I	Posgrado
17	25O	Temas Selectos de Biología Experimental I	Posgrado
18	25O	Temas Selectos de Biología Experimental III	Posgrado
19	25O	Trabajo de Investigación IV	Posgrado
20	25O	Trabajo de Redacción de Tesis I	Posgrado
21	25O	Trabajo Experimental I	Posgrado
22	25O	Trabajo Experimental I	Posgrado
23	25O	Trabajo Experimental I	Posgrado
24	25O	Trabajo Experimental I	Posgrado
25	25O	Trabajo Experimental III	Posgrado
26	25P	Proyecto de Investigación I	Licenciatura
27	25P	Proyecto de Investigación III	Licenciatura
28	25P	Respuesta de los Organismos al Estrés	Licenciatura
29	25P	Seminario de Escritura de Tesis II	Posgrado
30	25P	Seminario VII	Posgrado
31	25P	Temas Selectos de Biología Experimental II	Posgrado
32	25P	Trabajo de Investigación III	Posgrado
33	25P	Trabajo de Investigación IX	Posgrado
34	25P	Trabajo de Investigación IX	Posgrado
35	25P	Trabajo Experimental II	Posgrado
36	25P	Trabajo Experimental III	Posgrado
37	25P	Trabajo Experimental III	Posgrado
38	25I	Proyecto de Investigación II	Licenciatura
39	25I	Trabajo Experimental II	Posgrado
40	25I	Trabajo Experimental II	Posgrado
41	25I	Trabajo Experimental I	Posgrado
42	25I	Trabajo de Investigación VIII	Posgrado
43	25I	Trabajo de Investigación VIII	Posgrado
44	25I	Trabajo de Investigación II	Posgrado
45	25I	Temas Selectos de Biología Experimental II	Posgrado
46	25I	Temas Selectos de Biología Experimental I	Posgrado
47	25I	Seminario de Escritura de Tesis III	Posgrado
48	25I	Seminario de Escritura de Tesis I	Posgrado
49	25I	Respuesta de los Organismos al Estrés	Licenciatura
50	25I	Bioquímica y Biología Molecular I	Posgrado
51	25I	Temas Selectos de Biología Experimental II	Posgrado
52	24O	Trabajo Experimental I	Posgrado
53	24O	Trabajo de Investigación VII	Posgrado
54	24O	Trabajo de Investigación VII	Posgrado
55	24O	Trabajo de Investigación IX	Posgrado
56	24O	Trabajo de Investigación I	Posgrado
57	24O	Biología Celular	Posgrado
58	24O	Seminario de Escritura de Tesis II	Posgrado
59	24O	Epigenética	Licenciatura
60	24O	Proyecto de Investigación III	Licenciatura

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