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Perfil investigador
Esp
Dr. Kioko Rubí Guzmán Ramos

Professor
Departament of Health Sciences

Division of Biological and Health Sciences


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Lerma Campus

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Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Molecular mechanisms of memory formation
• Effect of hypercaloric diets on cognitive performance
• Dopaminergic system on Alzheimer's disease

Profile

Dr. Kioko Rubí Guzmán Ramos earned her degree in Biological Pharmaceutical Chemistry from the Faculty of Chemistry at the National Autonomous University of Mexico (UNAM). In 2005, she began her graduate studies in UNAM's Biomedical Sciences PhD program, where she investigated molecular processes underlying memory acquisition and consolidation.

She also worked with a murine model of Alzheimer's disease, describing dopamine-related deficits linked to cognitive impairment and examining how high-calorie diets influence cognitive performance. After completing two postdoctoral fellowships—one at Texas A&M University and another at UAM Lerma—she joined the Department of Health Sciences in 2015 as an Associate Professor and advanced to Full Professor in 2018.

From 2019 to 2023, she served as the Department of Health Sciences' leader. She belongs to Mexico's National System of Researchers (Level II) and is a member of both the Society for Neuroscience and the Mexican Society for Physiological Sciences.

Her research explores how chronic exposure to high-calorie diets affects cognitive function and investigates the mechanisms that drive these effects, aiming to develop pharmacological and non-pharmacological strategies to prevent or reverse their negative consequences.



Information provided by the academic staff

Research interests

• Molecular mechanisms of memory formation
• Effect of hypercaloric diets on cognitive performance
• Dopaminergic system on Alzheimer's disease

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
Osorio-Gómez, D., Vera-Rivera, G., Miranda, M.-I. and 2 more (...) (2026).Microdialysis Technique to Understand Neurochemical Mechanisms Underlying Memory Formation. Neuromethods,230145-171
Hernández-Ramírez, S., Guzmán-Ramos, K.R. (2026).The Impact of Nutrition, Genetics, Environment, and Common Issues on Adolescent Growth and Development. Advances in Experimental Medicine and Biology,1505123-143
OAGarcía-Gómez, L., Romero-Rebollar, C., Ferreira, G. and 18 more (...) (2026).Adolescents Who Are Overweight or Obese Exhibit Weaker Spatial and Verbal Working Memory Compared with Healthy-Weight Peers. Archives of Clinical Neuropsychology,41(3) 3
Reyes-Lagos, J.J., Guzmán-Ramos, K., Lomelí, J. and 8 more (...) (2025).Assessment of Short-Term Heart Rate and Breathing Rate Asymmetry in Diabetic and Non-Diabetic Individuals. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,3
OAReyes-Lagos, J.J., Guzmán-Ramos, K., Lomelí, J. and 8 more (...) (2025).Diabetes alters cardiorespiratory dynamics: insights from short-term recurrence quantification analysis of pulse-respiration quotient. Frontiers in Physiology,163
OAAbarca-Castro, E.A., Reyes-Lagos, J.J., Guzmán Ramos, K. and 6 more (...) (2025).Fetal development and the air pollution exposome: an integrative perspective of health pathways. Frontiers in Cellular Neuroscience,193|11
Alcaráz, N., Salcedo-Tello, P., González-Barrios, R. and 2 more (...) (2024).Underlying Mechanisms of the Protective Effects of Lifestyle Factors in the Prevention of Age-Related Diseases. Archives of Medical Research,55(5) 3
OAOsorio-Gómez, D., Perez, C.I., Salcedo-Tello, P. and 7 more (...) (2024).Early-life and chronic exposure to high-fat diet alters noradrenergic and glutamatergic neurotransmission in the male rat amygdala and hippocampus under cognitive challenges. Journal of Neuroscience Research,102(6) 3
OAOsorio-Gómez, D., Miranda, M.I., Guzmán-Ramos, K. and 1 more (...) (2023).Transforming experiences: Neurobiology of memory updating/editing. Frontiers in Systems Neuroscience,173
Hernández-Ramírez, S., Salcedo-Tello, P., Osorio-Gómez, D. and 5 more (...) (2022).Voluntary physical activity improves spatial and recognition memory deficits induced by post-weaning chronic exposure to a high-fat diet. Physiology and Behavior,2543
Ayala-Guerrero, L., García-delaTorre, P., Sánchez-García, S. and 1 more (...) (2022).Serum Levels of Glial Fibrillary Acidic Protein Association with Cognitive Impairment and Type 2 Diabetes. Archives of Medical Research,53(5) 501-5073
Guzmán-Ramos, K., Osorio-Gómez, D., Bermúdez-Rattoni, F. (2022).Cognitive Impairment in Alzheimer's and Metabolic Diseases: A Catecholaminergic Hypothesis. Neuroscience,497308-3233
OAOsorio-Gómez, D., Guzmán-Ramos, K., Bermúdez-Rattoni, F. (2022).Dopamine activity on the perceptual salience for recognition memory. Frontiers in Behavioral Neuroscience,16
Hernández-Ramírez, S., Osorio-Gómez, D., Escobar, M.L. and 5 more (...) (2021).Catecholaminergic stimulation restores high-sucrose diet-induced hippocampal dysfunction. Psychoneuroendocrinology,1273
Osorio-Gómez, D., Bermúdez-Rattoni, F., Guzmán-Ramos, K.R. (2021).Cortical neurochemical signaling of gustatory stimuli and their visceral consequences during the acquisition and consolidation of taste aversion memory. Neurobiology of Learning and Memory,181
OAPacheco-López, G., Pérez-Morales, M., Guzmán-Ramos, K.R. and 3 more (...) (2021).Editorial: Obesogenic Environmental Conditions Affect Neurodevelopment and Neurodegeneration. Frontiers in Neuroscience,153

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26P
Temas Selectos IIPosgrado
2
26P
Temas Selectos IPosgrado
3
26P
Seminario IPosgrado
4
26P
Trabajo de Redacción de Tesis IIIPosgrado
5
26P
Eje Integrador IV: Anteproyecto TerminalLicenciatura
6
26P
NeurofisiologíaLicenciatura
7
26P
Fisiología de la Nutrición HumanaLicenciatura
8
26I
Aprendizaje y MemoriaLicenciatura
9
26I
Taller de Comprensión de Textos CientíficosLicenciatura
10
26I
Análisis Experimental de la ConductaLicenciatura
11
26I
Eje Integrador III: Perspectiva Biopsicosocial de la ConductaLicenciatura
12
26I
Seminario Optativo Interdivisional IILicenciatura
13
26I
Seminario Optativo Interdivisional IIILicenciatura
14
26I
Seminario Optativo Interdivisional VLicenciatura
15
26I
Taller de Comprensión de Textos CientíficosLicenciatura
16
26I
Trabajo de Redacción de Tesis IIPosgrado
17
25O
Aprendizaje y MemoriaLicenciatura
18
25O
Eje Integrador I: el Método CientíficoLicenciatura
19
25P
Eje Integrador IV: Anteproyecto TerminalLicenciatura
20
25P
Fisiología de la Nutrición HumanaLicenciatura
21
25P
NeuroquímicaLicenciatura
22
25I
Seminario Optativo InterdIVisional IVLicenciatura
23
25I
Análisis Experimental de la ConductaLicenciatura
24
25I
Comprensión de textos Licenciatura
25
25I
Eje Integrador III: Perspectiva Biopsicosocial de la ConductaLicenciatura
26
25I
Seminario Optativo Interdivisional IIILicenciatura
27
25I
Seminario Optativo Interdivisional VIILicenciatura
28
25I
Taller de Comprensión de Textos CientíficosLicenciatura
29
24O
Aprendizaje y MemoriaLicenciatura
30
24O
Eje Integrador I: el Método CientíficoLicenciatura
31
24O
Proyecto Terminal de Psicología Biomédica IILicenciatura
32
24P
Proyecto Terminal de Psicología Biomédica ILicenciatura
33
24P
Fisiología de la Nutrición HumanaLicenciatura
34
24P
NeurofisiologíaLicenciatura
35
24P
Proyecto Terminal de Psicología Biomédica IILicenciatura
36
24I
Seminario Optativo Interdivisional VLicenciatura
37
24I
Análisis Experimental de la ConductaLicenciatura
38
24I
Comprensión de textos Licenciatura
39
24I
Eje Integrador III: Perspectiva Biopsicosocial de la ConductaLicenciatura
40
24I
Proyecto Terminal de Psicología Biomédica ILicenciatura
41
24I
Seminario Optativo Interdivisional IIILicenciatura
42
24I
Seminario Optativo InterdIVisional IVLicenciatura
43
24I
Taller de Comprensión de Textos CientíficosLicenciatura
44
24I
Trabajo de Redacción de Tesis IIIPosgrado
45
23O
Aprendizaje y MemoriaLicenciatura
46
23O
Eje Integrador I: el Método CientíficoLicenciatura
47
23O
Trabajo de Redacción de Tesis IIPosgrado
48
23P
QuímicaLicenciatura
49
23P
NeurofisiologíaLicenciatura
50
23P
Proyecto Terminal de Psicología Biomédica IILicenciatura
51
23P
Tópicos Selectos Interdisciplinarios VILicenciatura
52
23P
Trabajo de Redacción de Tesis IPosgrado
53
23I
Taller de Comprensión de Textos CientíficosLicenciatura
54
23I
Análisis Experimental de la ConductaLicenciatura
55
23I
Comprensión de textos Licenciatura
56
23I
Eje Integrador III: Perspectiva Biopsicosocial de la ConductaLicenciatura
57
23I
Proyecto Terminal de Psicología Biomédica ILicenciatura
58
23I
Seminario VIIPosgrado
59
23I
Trabajo de Investigación IXPosgrado
60
22O
Aprendizaje y MemoriaLicenciatura
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Universidad Autónoma Metropolitana, 2026.