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Perfil investigador
Esp
Dr. Sergio Andrés Alatorre Santamaria

Professor
Departament of Biotechnology

Division of Biological and Health Sciences


Level 1
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being

• 9 Industry, Innovation and Infrastructure


Research interests

• Food additives preparation
• Food decontamination
• Bioactive compounds synthesis
• Recovery of fine chemicals from food waste

Profile

Professor Sergio Alatorre Santamaria completed his undergraduate studies (Food Chemistry) and Master's degree (Biochemical Sciences) at the Faculty of Chemistry of the National Autonomous University of Mexico. He later obtained his Ph.D. degree "Magna Cum Laude" in Organic Chemistry (Biocatalysis) at the University of Oviedo (Spain), studies carried out between 2006 and 2010. After a year as an associate professor at the Unidad Xochimilco of the UAM, he did a postdoctoral stay in the research group of Professor Tomáš Hudlický at Brock University (Canada) between 2011 and 2012. During his Ph.D. studies and postdoctoral stay, he was a grantee of the Mexican (CONACYT) and Canadian (PDRF-CBIE) governments, respectively.

Since 2013 he has been attached to the Food Biotechnology group, in the Department of Biotechnology, at the Universidad Autónoma Metropolitana, Unidad Iztapalapa, with the category of Professor C Full Time. He is a member of the National System of Researchers (SNI), Level I, and is also a Professor with Desirable Profile (PRODEP).

He has participated in the direction and advising of undergraduate, specialty, Master's, and Doctoral theses. He is a full-time professor, teaching theoretical and practical courses in the Biotechnology department in introductory and semi-advanced organic chemistry.

He has published over 20 articles in national and international peer-reviewed journals, five didactic books, and three book chapters. He has also participated as an academic representative before the Divisional Council of CBS in the Iztapalapa Campus. He was the coordinator of the Editorial Committee within the same Division and is currently Head of the Academic Area of Food.

He has also participated in several projects funded by the University, CONACYT, and foreign governments.

His lines of research are the synthesis of food additives through environmentally friendly biocatalytic techniques, the development of alternative methods for decontaminating mycotoxins in food, and the preparation of value-added compounds with nutraceutical potential.

Finally, he has established research links with groups at the Universidad Autónoma del Estado de Hidalgo, the Universidad Nacional Autónoma de México, and the University of Windsor (Canada).



Information provided by the academic staff

Research interests

• Food additives preparation
• Food decontamination
• Bioactive compounds synthesis
• Recovery of fine chemicals from food waste

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAGranados-Martínez, M., Guzmán-Rodríguez, F., Cruz-Guerrero, A. and 1 more (...) (2026).Valorization of requesón Cheese Whey through Synthesis of Galactooligosaccharides with Fungal and Recombinant β-Galactosidases. ACS Food Science and Technology,6(4) 986-9959
OAPavón-Chimal, M.E., Alatorre-Santamaría, S., Guzmán-Rodríguez, F. and 3 more (...) (2026).Optimized of sonication-assisted extraction of α-L-fucosidase from Bifidobacterium spp. for the synthesis of fucosylated oligosaccharides. Revista Mexicana de Ingeniera Quimica,25(3)
OATorres-Ochoa, C., Jiménez-Pérez, C., Tello-Solís, S.R. and 4 more (...) (2026).Calcium enhances hydrolytic and transfucosylation activities in α-L-fucosidase from Thermotoga maritima through catalytic loop stabilization: an MD simulation study. Applied Microbiology and Biotechnology,110(1)
OAPatlan-Velázquez, L.-F., González-Olivares, L.-G., García-Garibay, M. and 5 more (...) (2026).Bioactive Peptide-Enriched Requeson: A Functional Dairy Product From Whey Fermentation. Food Science and Nutrition,14(4) 12
OARobles-Arias, M.A., Jímenez-Pérez, C., Gómez-Castro, C.Z. and 7 more (...) (2026).Effect of temperature on the structure of α-l-fucosidase from Thermotoga maritima: implications from molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics,44(11) 4977-49913
OAHernández-Martínez, A., Roldán-Hernández, L., Razmkhah, K. and 4 more (...) (2025).Evaluation of aflatoxin M1 binding capacity of kefir exopolysaccharides produced with different fermentation media. International Dairy Journal,169
OAPatlan-Velazquez, L.F., González-Olivares, L.G., García-Garibay, M. and 4 more (...) (2025).Whey as a substrate for biogenic production of exopolysaccharide. Revista Mexicana de Ingeniera Quimica,24(1)
OACarrero-Puentes, S., Jiménez-Pérez, C., Guzmán-Rodríguez, F. and 6 more (...) (2025).Effect of an exopolysaccharide-producing strain of Lactobacillus delbrueckii subsp. bulgaricus NCFB 2772 on the yield and quality of Requeson (Mexican cheese) added with a probiotic. Journal of Dairy Research,92(4) 566-573
OAJiménez-Pérez, C., Roldán-Hernández, L., Cruz-Guerrero, A. and 1 more (...) (2024).Evaluation of the aflatoxin M1 retention capacity in a polysaccharide obtained by fermenting milk with kefir grains. Revista Mexicana de Ingeniera Quimica,23(2) 9
Patlan-Velázquez, L.-F., González-Olivares, L.-G., García-Garibay, M. and 4 more (...) (2024).Effect of biogenic exopolysaccharides in characteristics and stability of a novel Requeson-type cheese. Food Bioscience,59
OAMagacz, M., Alatorre-Santamaría, S., Kędziora, K. and 7 more (...) (2023).Modified Lactoperoxidase System as a Promising Anticaries Agent: In Vitro Studies on Streptococcus mutans Biofilms. International Journal of Molecular Sciences,24(15)
OAJiménez-Pérez, C., Guzmán-Rodríguez, F., Cruz-Guerrero, A.E. and 1 more (...) (2023).The dual role of fucosidases: tool or target. Biologia,78(7) 1773-17883
OAPavón-Chimal, M.E., Jiménez-Pérez, C., Guzmán-Rodríguez, F. and 6 more (...) (2023).An In silico Analysis of Enzyme-Substrate Interaction in α-L-Fucosidases Belonging to the GH29 Family. Biointerface Research in Applied Chemistry,13(5)
OACastañeda-Ovando, A., Moreno-Vilet, L., Jaimez-Ordaz, J. and 7 more (...) (2023).Aguamiel syrup as a technological diversification product: Composition, bioactivity and present panorama. Future Foods,83
Guzmán-Rodríguez, F., Alatorre-Santamaría, S., Cruz-Guerrero, A. (2023).Human Milk Oligosaccharides (HMOS). Handbook of Food Bioactive Ingredients: Properties and Applications,1383-1411
Alatorre-Santamaría, S., Cruz-Guerrero, A., Guzmán-Rodríguez, F. (2023).Fructooligosaccharides (FOS). Handbook of Food Bioactive Ingredients: Properties and Applications,1271-13003
Pavón-Chimal, M.E., Jiménez-Pérez, C., Guzmán-Rodriguez, F. and 6 more (...) (2023).Mechanistic insight into the synthesis of fucooligosaccharides by α-L-fucosidase from Thermotoga maritima belonging to the GH29 family: in silico study. Biologia,78(7) 1825-1832
OANavarro, A., Gimeno, M., Alatorre-Santamaría, S. and 1 more (...) (2022).Benign and straightforward synthesis of lignan-type dimers using crude peroxidase from red radish (Raphanus sativus var sativus). Revista Mexicana de Ingeniera Quimica,21(2)
OACarrero-Puentes, S., Fuenmayor, C., Jiménez-Pérez, C. and 6 more (...) (2022).Development and characterization of an exopolysaccharide-functionalized acid whey cheese (requesón) using Lactobacillus delbrueckii ssp. bulgaricus. Journal of Food Processing and Preservation,46(6)
Pérez-Escalante, E., Alatorre-Santamaría, S., Castañeda-Ovando, A. and 5 more (...) (2022).Human milk oligosaccharides as bioactive compounds in infant formula: recent advances and trends in synthetic methods. Critical Reviews in Food Science and Nutrition,62(1) 181-214
OARobles-Arias, M.A., Guzmán-Rodriguez, F., García-Garibay, M. and 4 more (...) (2021).α-L-fucosidase from Thermotoga maritima: Hydrolytic and transfucosylation activities. Revista Mexicana de Ingeniera Quimica,20(3)
OAde la Vega, M.I.C., Alatorre-Santamaría, S., Gómez-Ruiz, L. and 5 more (...) (2021).Influence of oat β-glucan on the survival and proteolytic activity of lactobacillus rhamnosus gg in milk fermentation: Optimization by response surface. Fermentation,7(4)
Guzmán-Rodríguez, F., Alatorre-Santamaría, S., Gómez-Ruiz, L. and 3 more (...) (2021).Synthesis of fucosylated oligosaccharides with α-l-fucosidase from Thermotoga maritima immobilized on Eupergit® CM. Extremophiles,25(3) 311-317
Jiménez-Pérez, C., Alatorre-Santamaría, S., Tello-Solís, S.R. and 4 more (...) (2021).Analysis of aflatoxin m1 contamination in milk and cheese produced in mexico: A review. World Mycotoxin Journal,14(3) 269-285
Robles-Arias, M.A., García-Garibay, M., Alatorre-Santamaría, S. and 5 more (...) (2021).Improvement of Fucosylated Oligosaccharides Synthesis by α-L-Fucosidase from Thermotoga maritima in Water-Organic Cosolvent Reaction System. Applied Biochemistry and Biotechnology,193(11) 3553-3569
Jiménez-Pérez, C., Tello-Solís, S.R., Gómez-Castro, C.Z. and 6 more (...) (2020).Spectroscopic studies and molecular modelling of the aflatoxin M1-bovine α-lactalbumin complex formation. Journal of Photochemistry and Photobiology B: Biology,209

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26P
Temas Selectos de Biotecnología IIPosgrado
2
26P
Trabajo Experimental VIIPosgrado
3
26P
Seminario de Informe TerminalPosgrado
4
26P
Tópicos de Biotecnología IIPosgrado
5
26P
Química Orgánica IILicenciatura
6
26I
Trabajo Experimental IIIPosgrado
7
26I
Química Orgánica IILicenciatura
8
26I
Trabajo Experimental IXPosgrado
9
26I
Trabajo Experimental VIPosgrado
10
25O
Trabajo Experimental VPosgrado
11
25O
Química Orgánica IILicenciatura
12
25O
Trabajo Experimental IIPosgrado
13
25P
Química Orgánica IILicenciatura
14
25P
Temas Selectos de Biotecnología IIPosgrado
15
25P
Tópicos en Biotecnología IPosgrado
16
25P
Trabajo Experimental IPosgrado
17
25P
Trabajo Experimental IVPosgrado
18
25I
Seminario de Revisión Bibliográfica y Proyecto ExperimentalPosgrado
19
25I
Química Orgánica IILicenciatura
20
25I
Seminario de Proyecto DoctoralPosgrado
21
24O
Química Orgánica IILicenciatura
22
24P
Química Orgánica IILicenciatura
23
24P
Química y Bioquímica de AlimentosPosgrado
24
24P
Seminario de Informe TerminalPosgrado
25
24I
Química Orgánica IILicenciatura
26
24I
Proyecto de Investigación IIILicenciatura
27
24I
Tópicos en Biotecnología IPosgrado
28
24I
Trabajo Experimental IIIPosgrado
29
23O
Tópicos en Biotecnología IPosgrado
30
23O
Proyecto de Investigación IILicenciatura
31
23O
Química Orgánica IILicenciatura
32
23O
Tópicos de Biotecnología IIPosgrado
33
23O
Trabajo Experimental IIPosgrado
34
23P
Proyecto de Investigación ILicenciatura
35
23P
Química Orgánica IILicenciatura
36
23P
Trabajo Experimental IPosgrado
37
23I
Seminario de Revisión Bibliográfica y Proyecto ExperimentalPosgrado
38
23I
Trabajo Experimental XIIPosgrado
39
23I
Trabajo Experimental XIIPosgrado
40
23I
Química Orgánica IILicenciatura
41
22O
Trabajo Experimental IXPosgrado
42
22O
Trabajo Experimental XIPosgrado
43
22O
Trabajo Experimental IIIPosgrado
44
22O
Química Orgánica IILicenciatura
45
22P
Química Orgánica IILicenciatura
46
22P
Trabajo Experimental IIPosgrado
47
22P
Trabajo Experimental XPosgrado
48
22P
Trabajo Experimental XIPosgrado
49
22I
Química Orgánica IILicenciatura
50
22I
Química Orgánica IILicenciatura
51
22I
Seminario de Revisión BibliográficaPosgrado
52
22I
Trabajo Experimental IPosgrado
53
22I
Trabajo Experimental XPosgrado
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Universidad Autónoma Metropolitana, 2026.