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Perfil investigador
Esp
Dr. Verónica Souza Arroyo

Professor
Departament of Health Sciences

Division of Biological and Health Sciences


Level 1
Member of the National System of Researchers
(SNII)

Medicine and Health Sciences



Iztapalapa Campus

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Academic Work

• Scopus

Sites of interest

• PubMed

Sustainable Development Goals

• 3 Good Health and Well-being

• 4 Quality Education


Research interests

• Cadmium Toxicity
• Metallothionein Induction
• Cell Signaling
• Oxidative Stress
• Liver Damage

Profile

Professor Verónica Souza Arroyo completed her undergraduate studies in Experimental Biology at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus, a Master's degree in Biomedical Sciences at the Faculty of Medicine at Universidad Nacional Autónoma de México (UNAM) and a Ph.D. in Biological Sciences at UAM. She has been a Professor in the Laboratory of Cell Physiology of the Department of Health Sciences of the DCBS for 30 years, with a research line in Biochemical and Molecular Alterations that cadmium induces in various cell types of hepatic origin and its relationship with oxidative stress.

She was named SNI Candidate and then National Researcher Level I. She has been approved several research projects by Conacyt and by UAM. She has taught several classes at the undergraduate and graduate levels in Experimental Biology. She has advised social services, and research projects and has graduated nine masters and doctoral students in Experimental Biology. She has published 46 co-authored articles in peer-reviewed journals, 11 book chapters, and several national and international conferences. She has received awards for Research and Areas from the UAM. She was a member of the committee of the Master in Experimental Biology of the DCBS of the UAM Iztapalapa Campus.

Among the contributions of her research work are some biochemical and molecular alterations that cadmium induces, such as DNA damage and antioxidant enzymes, as well as the generation of free radicals and metallothionein-II protein, through the EGFR/Src signaling pathway in hepatocytes. From the findings obtained, it is important to highlight the induction of metallothionein-II, by an alteration in the autophagy process, in mouse hepatocytes fed with a high cholesterol diet and to further advance in the basic knowledge of the mechanisms of cadmium-induced damage.



Information provided by the academic staff

Research interests

• Cadmium Toxicity
• Metallothionein Induction
• Cell Signaling
• Oxidative Stress
• Liver Damage

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OASánchez-Rodríguez, M., Lazzarini-Lechuga, R., Souza-Arroyo, V. and 8 more (...) (2025).GDF11 downregulates FOXP3 in T-cell acute lymphoblastic leukemia-derived cells and associates with restraining aggressiveness. Oncology Research,33(8) 2075-2084| 3 |
OARosales-Muñoz, G.J., Souza-Arroyo, V., Bucio-Ortiz, L. and 3 more (...) (2025).Correction: Acute pancreatitis experimental models, advantages and disadvantages (Journal of Physiology and Biochemistry, (2025), 81, 3, (539-556), 10.1007/s13105-025-01091-w). Journal of Physiology and Biochemistry,81(3) 831-832| 3 |
OAEscobedo-Calvario, A., Chávez-Rodríguez, L., Souza-Arroyo, V. and 8 more (...) (2025).Growth differentiation factor 11 modulates metabolism, mitigating the pro-tumoral behavior provided by M2-like macrophages in hepatocellular carcinoma-derived cells. World Journal of Gastroenterology,31(40) | 3 |
OARosales-Muñoz, G.J., Souza-Arroyo, V., Bucio-Ortiz, L. and 3 more (...) (2025).Acute pancreatitis experimental models, advantages and disadvantages. Journal of Physiology and Biochemistry,81(3) 539-556
Gerardo-Ramírez, M., German-Ramirez, N., Escobedo-Calvario, A. and 6 more (...) (2023).The hepatic effects of GDF11 on health and disease. Biochimie,208129-140| 3 |
Palestino-Domínguez, M., Escobedo-Calvario, A., Salas-Silva, S. and 7 more (...) (2023).Erk1/2 signaling mediates the HGF-induced protection against ethanol and acetaldehyde-induced toxicity in the pancreatic RINm5F cell line. Journal of Biochemical and Molecular Toxicology,37(4)
Souza-Arroyo, V., Fabián, J.J., Bucio-Ortiz, L. and 3 more (...) (2022).The mechanism of the cadmium-induced toxicity and cellular response in the liver. Toxicology,480| 3 |
OAQuevedo-Ocampo, J., Escobedo-Calvario, A., Souza-Arroyo, V. and 5 more (...) (2022).Folate Metabolism in Hepatocellular Carcinoma. What Do We Know So Far?. Technology in Cancer Research and Treatment,21| 3 |
Salas-Silva, S., López-Ramirez, J., Barrera-Chimal, J. and 9 more (...) (2022).Hepatocyte growth factor reverses cholemic nephropathy associated with α-naphthylisothiocyanate-induced cholestasis in mice. Life Sciences,295
OAChávez-Rodríguez, L., Escobedo-Calvario, A., Salas-Silva, S. and 5 more (...) (2021).Fructose Consumption and Hepatocellular Carcinoma Promotion. Livers,1(4) 250-262| 3 |
OASimoni-Nieves, A., Salas-Silva, S., Chávez-Rodríguez, L. and 10 more (...) (2021).The consumption of cholesterol-enriched diets conditions the development of a subtype of hcc with high aggressiveness and poor prognosis. Cancers,13(7) | 3 |
Hernandez, S., Simoni-Nieves, A., Gerardo-Ramírez, M. and 14 more (...) (2021).GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cells. Journal of Cellular Physiology,236(5) 4076-4090| 3 |
OASimoni-Nieves, A., Clavijo-Cornejo, D., Salas-Silva, S. and 6 more (...) (2021).HGF/c-Met regulates p22phox subunit of the NADPH oxidase complex in primary mouse hepatocytes by transcriptional and post-translational mechanisms. Annals of Hepatology,25
Bello-Monroy, O., Mata-Espinosa, D., Enríquez-Cortina, C. and 10 more (...) (2020).Hepatocyte growth factor enhances the clearance of a multidrug-resistant Mycobacterium tuberculosis strain by high doses of conventional chemotherapy, preserving liver function. Journal of Cellular Physiology,235(2) 1637-1648| 3 |
Salas-Silva, S., Simoni-Nieves, A., Razori, M.V. and 10 more (...) (2020).HGF induces protective effects in α-naphthylisothiocyanate-induced intrahepatic cholestasis by counteracting oxidative stress. Biochemical Pharmacology,174

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
Temas Selectos de Respuesta Celular al EstrésLicenciatura
2
25O
Trabajo Experimental IIIPosgrado
3
25O
Trabajo de Investigación IVPosgrado
4
25O
Apoptosis y SenescenciaLicenciatura
5
25P
Temas Selectos de Respuesta Celular al EstrésLicenciatura
6
25P
Trabajo Experimental IIPosgrado
7
25P
Trabajo de Investigación IIIPosgrado
8
25I
Transporte y Comunicación CelularLicenciatura
9
25I
Temas Selectos de Respuesta Celular al EstrésLicenciatura
10
25I
Trabajo Experimental IPosgrado
11
25I
Trabajo de Investigación IIPosgrado
12
24O
Temas Selectos de Respuesta Celular al EstrésLicenciatura
13
24O
Trabajo de Investigación IPosgrado
14
24O
Temas Selectos de Biología Experimental IPosgrado
15
24O
Transporte y Comunicación CelularLicenciatura
16
24P
Estructura y Función Celular ILicenciatura
17
24P
Temas Selectos de Respuesta Celular al EstrésLicenciatura
18
24P
Trabajo Experimental IIIPosgrado
19
24P
Trabajo Experimental IIIPosgrado
20
24I
Trabajo Experimental IIPosgrado
21
24I
Temas Selectos de Respuesta Celular al EstrésLicenciatura
22
24I
Trabajo Experimental IIPosgrado
23
24I
Temas Selectos de Biología Experimental IIPosgrado
24
24I
Transporte y Comunicación CelularLicenciatura
25
24I
Temas Selectos de Biología Experimental IIPosgrado
26
23O
Transporte y Comunicación CelularLicenciatura
27
23O
Temas Selectos de Respuesta Celular al EstrésLicenciatura
28
23O
Temas Selectos de Biología Experimental IPosgrado
29
23O
Trabajo Experimental IPosgrado
30
23O
Trabajo Experimental IPosgrado
31
23P
Temas Selectos de Respuesta Celular al EstrésLicenciatura
32
23P
Estructura y Función Celular IILicenciatura
33
23I
Temas Selectos de Respuesta Celular al EstrésLicenciatura
34
23I
Transporte y Comunicación CelularLicenciatura
35
23I
Temas Selectos de Biotecnología IIPosgrado
36
22O
Transporte y Comunicación CelularLicenciatura
37
22O
Temas Selectos de Respuesta Celular al EstrésLicenciatura
38
22P
Estructura y Función Celular ILicenciatura
39
22P
Temas Selectos de Respuesta Celular al EstrésLicenciatura
40
22I
Temas Selectos de Respuesta Celular al EstrésLicenciatura
41
22I
Transporte y Comunicación CelularLicenciatura
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Universidad Autónoma Metropolitana, 2025.