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Perfil investigador
Esp
Dr. Sergio Huerta Ochoa

Professor
Departament of Biotechnology

Division of Biological and Health Sciences


Level 3
Member of the National System of Researchers
(SNII)

Agriculture, Farming, Forestry and Ecosystem Sciences



Iztapalapa Campus

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Sustainable Development Goals

• 9 Industry, Innovation and Infrastructure

• 12 Responsible Consumption and Production


Research interests

• Design and optimization of biotransformation bioprocesses
• Whole-cell biocatalysis using partitioning bioreactors
• Biocatalysis in solid / gas systems
• Use of agro-industrial waste by solid-state fermentation

Profile

Professor Sergio Huerta-Ochoa was born in Orizaba Veracruz on July 16, 1956. He studied for a bachelor’s degree in chemical engineering at the Universidad Veracruzana in Orizaba Veracruz, obtaining the degree in 1979. He completed his Master's studies in Chemical Engineering at the Universidad Autónoma Metropolitana, Iztapalapa Campus in Mexico City, obtaining the degree in 1984. He received his PhD from the University of Reading in the UK in 1993.

He has been part of the staff of the Biotechnology Department of UAM for 43 years. He won the 2017 Teaching Award from the Division of Biological and Health Sciences. He spent a sabbatical year (2007–2008) as an Honorary Associate Researcher in the Biochemical Engineering Department at London University College, United Kingdom.

His experience focuses mainly on engineering bioconversion processes using whole-cells in partitioning and solid/gas bioreactors. His last three Conahcyt projects as a technical manager are: Design and modeling of a bioreactor for the biosynthesis of lactones with whole-cells in the aqueous-ionic liquid two-phase system (2004-2007); Scale-down strategies for partitioning bioreactors (2008-2011); Bioconversion of citrus flavones using whole-cells in a partitioning bioreactor (2015-2018). He is the co-author of 65 articles in International Indexed Journals (Index h 20, Scopus-Elsevier, March 2025), 22 book chapters, and edited 4 books: "Advances and applications of partitioning bioreactors" Elsevier; “Whole-cell biocatalysis: Fundamentals and Applications” Elsevier; and "Reactores Enzimáticos" and "Avances en purificación y aplicación de enzimas en biotecnología" printed by our university.

He has supervised 14 Master's theses and 9 Doctoral´s theses. As Director of the Doctoral thesis "Study of the mechanisms of mass transfer, kinetic and deactivation of a three-phase partitioning bioreactor using whole-cells" won the Alfredo Sánchez Marroquín Award in 2015, awarded by the Mexican Society of Biotechnology and Bioengineering (SMBB) and Yakult. As Co-Director in the Doctoral thesis "Technological production of 2-Phenylethanol using a recovery technique with a hybrid material based on polyurethane and keratin fiber," the "State Prize for Science, Technology and Innovation Durango 2018 won the best Doctoral thesis in the category "Engineering, Industrial and Technological Development”.

Since 2017, he has been part of the Editorial Board of the Biochemical Engineering Journal (Elsevier). It belongs to the National Researchers System (SNI) in "Level III". He has been a member of the SMBB since 1995 and the Mexican Academy of Sciences (AMC) since 2014.



Information provided by the academic staff

Research interests

• Design and optimization of biotransformation bioprocesses
• Whole-cell biocatalysis using partitioning bioreactors
• Biocatalysis in solid / gas systems
• Use of agro-industrial waste by solid-state fermentation

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
Dorantes-Landa, D.N., Hernandez-Aguirre, A., Ricardez-Sandoval, L. and 2 more (...) (2025).A systematic approach to defining a unit cell for fluid dynamics in packed beds with low tube-to-particle diameter ratio. AIChE Journal,71(4)
OAHernández-Alonso, J.U., Pichardo-Sánchez, M.A., Huerta-Ochoa, S. and 7 more (...) (2025).Impact of Co-Substrates on the Production of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Burkholderia thailandensis E264. Materials,18(15)
OAGómez-Ramos, G.A., Prado-Barragán, L.A., Rivera, B.A. and 5 more (...) (2025).Bioreactor Engineering for Circular Economy: Bioactive Compound Production in Solid-State Fermentation—Review. Chemical Engineering and Technology,48(1)
Huerta-Ochoa, S., Prado-Barragán, L.A., Aguilar, C.N. (2025).Preface. Whole Cell Biocatalysis: Fundamentals and Applications,xix-xx
Huerta-Ochoa, S. (2025).Advantages and new potential applications of whole-cell biocatalysis. Whole Cell Biocatalysis: Fundamentals and Applications,1-19| 7 |
Huerta-Ochoa, S., Prado-Barragán, L.A., Aguilar, C.N. (2025).Whole-Cell Biocatalysis: Fundamentals and Applications. Whole Cell Biocatalysis: Fundamentals and Applications,1-316| 7 |
Cruz-Martínez, Y.A., Castillo-Araiza, C.O., Castillo-Rosales, E. and 1 more (...) (2024).Effect of adsorption/desorption of substrates/products during isobutyl propionate synthesis over CalB Immo Plus™ in solid/gas biocatalysis. Biochemical Engineering Journal,208| 9 |
OALondoño-Hernández, L., García-Gómez, M.D.J., Huerta-Ochoa, S. and 3 more (...) (2024).Effect of Glucose Concentration on the Production of Proteolytic Extract by Different Strains of Aspergillus under Solid-State Fermentation. Fermentation,10(2)
OABarrios-Nolasco, A., Castillo-Araiza, C.O., Huerta-Ochoa, S. and 3 more (...) (2024).Evaluating the Performance of Yarrowia lipolytica 2.2ab in Solid-State Fermentation under Bench-Scale Conditions in a Packed-Tray Bioreactor. Fermentation,10(7)
Couder-García, M., Prado-Barragán, L.A., Huerta-Ochoa, S. and 1 more (...) (2024).Assessing the Impact of Transport Phenomena on Modeling and Optimization of Solid-State Fermentation for the Revalorization of Agro-Industrial Residues in a Wall‐Cooled Packed‐Bed Bioreactor. Chemical Engineering Research and Design,210365-381
OAHernández-Guzmán, C., Hernández-Montiel, L.G., Velázquez-Lizarraga, A.E. and 6 more (...) (2024).Enhanced Antioxidant, Antifungal, and Herbicidal Activities through Bioconversion of Diosgenin by Yarrowia lipolytica P01a. Plants,13(18) | 2 |
Cordero-Soto, I.N., Huerta-Ochoa, S., Prado-Barragán, L.A. and 3 more (...) (2024).Food by-products potential use for flavor enhancers production. Enzymatic Processes for Food Valorization,129-143| 2 |
OABuenrostro-Figueroa, J.J., Nevárez-Moorillón, G.V., Chávez-González, M.L. and 6 more (...) (2023).Improved Extraction of High Value-Added Polyphenols from Pomegranate Peel by Solid-State Fermentation. Fermentation,9(6)
Huerta-Ochoa, S., Castillo-Araiza, C.O., Cordero-Soto, I.N. and 3 more (...) (2023).Fundamentals and Applications of Solid/Gas Biocatalysis. Some Key Topics in Chemistry and Biochemistry for Biotechnologists,64-90
OAAmador-Mendoza, A., Juárez-Barrientos, J.M., Hernández-Hernández, H. and 4 more (...) (2022).EVALUATION OF COMBINED PROCESSES: CHITIN PURIFICATION FROM SHRIMP (Penaeus sp) AND GRASSHOPPER (Sphenarium purpurascens) EXOSKELETONS. Tropical and Subtropical Agroecosystems,25(3)
García-Martínez, L.E., Castillo-Araiza, C.O., Quijano, G. and 1 more (...) (2022).On the modelling and surface response analysis of a non-conventional wall-cooled solid/gas bioreactor with application in esterification. Chemical Engineering Journal,437
OACordero-Soto, I.N., Castillo-Araiza, C.O., Rutiaga-Quiñones, O.M. and 6 more (...) (2021).Intensification of 2-phenylethanol production using an aerated system assisted by a membrane-based solvent extraction technique. Revista Mexicana de Ingeniera Quimica,20(2) 739-750
Reyes-Cervantes, A., Robles-Morales, D.L., Téllez-Jurado, A. and 3 more (...) (2021).Evaluation in the performance of the biodegradation of herbicide diuron to high concentrations by Lysinibacillus fusiformis acclimatized by sequential batch culture. Journal of Environmental Management,291| 15 |
Hernández-Guzmán, C., Prado-Barragán, A., Gimeno, M. and 4 more (...) (2020).Whole-cell bioconversion of naringenin to high added value hydroxylated compounds using Yarrowia lipolytica 2.2ab in surface and liquid cultures. Bioprocess and Biosystems Engineering,43(7) 1219-1230
Cordero-Soto, I.N., Castillo-Araiza, C.O., García-Martínez, L.E. and 2 more (...) (2020).Solid/gas biocatalysis for aroma production: An alternative process of white biotechnology. Biochemical Engineering Journal,164| 3| 9 |

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
Ingeniería EnzimáticaLicenciatura
2
25P
Ingeniería EnzimáticaLicenciatura
3
25P
Seminario de Informe TerminalPosgrado
4
25P
Seminario de Examen PredoctoralPosgrado
5
25I
Ingeniería EnzimáticaLicenciatura
6
25I
Seminario de Informe TerminalPosgrado
7
25I
Temas Selectos de Biotecnología IPosgrado
8
25I
Temas Selectos de Biotecnología IIPosgrado
9
24O
Ingeniería EnzimáticaLicenciatura
10
24O
Trabajo Experimental XIIPosgrado
11
24P
Seminario de Informe TerminalPosgrado
12
24P
Trabajo Experimental XIPosgrado
13
24P
Ingeniería EnzimáticaLicenciatura
14
24P
Proyecto de Investigación IIILicenciatura
15
24I
Proyecto de Investigación IILicenciatura
16
24I
Ingeniería EnzimáticaLicenciatura
17
24I
Trabajo Experimental IIIPosgrado
18
24I
Trabajo Experimental IIIPosgrado
19
24I
Trabajo Experimental XPosgrado
20
24I
Seminario de Examen PredoctoralPosgrado
21
24I
EnzimologíaPosgrado
22
23O
Proyecto de Investigación ILicenciatura
23
23O
Proyecto de Investigación IPosgrado
24
23O
Trabajo Experimental IIPosgrado
25
23O
Ingeniería EnzimáticaLicenciatura
26
23O
Trabajo Experimental IIPosgrado
27
23P
Ingeniería EnzimáticaLicenciatura
28
23P
Trabajo Experimental IPosgrado
29
23P
Trabajo Experimental IPosgrado
30
23P
Trabajo Experimental IXPosgrado
31
23P
Seminario de Examen PredoctoralPosgrado
32
23I
Seminario de Examen PredoctoralPosgrado
33
23I
Trabajo Experimental VIIIPosgrado
34
23I
Seminario de Revisión Bibliográfica y Proyecto ExperimentalPosgrado
35
23I
Ingeniería EnzimáticaLicenciatura
36
22O
Ingeniería EnzimáticaLicenciatura
37
22O
Trabajo Experimental VIIPosgrado
38
22O
Investigación Doctoral IVPosgrado
39
22P
Ingeniería EnzimáticaLicenciatura
40
22P
Trabajo Experimental VIPosgrado
41
22P
Trabajo Experimental IXPosgrado
42
22I
Ingeniería EnzimáticaLicenciatura
43
22I
Trabajo Experimental VIIIPosgrado
44
22I
Trabajo Experimental VPosgrado
Information provided by the Dirección de Sistemas Escolares
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Universidad Autónoma Metropolitana, 2026.