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Perfil investigador
Esp
Dr. Sergio Huerta Ochoa

Professor
Departament of Biotechnology

Division of Biological and Health Sciences


Level 3
Member of the National System of Researchers
(SNII)

Agriculture, Farming, Forestry and Ecosystem Sciences



Iztapalapa Campus

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Sites of interest

• Web of science

Sustainable Development Goals

• 4 Quality Education

• 9 Industry, Innovation, and Infrastructure

• 12 Responsible Consumption and Production


Research interests

• Design and optimization of biotransformation bioprocesses
• Biocatalysis in organic synthesis using whole cells
• Biocatalysis in solid/gas systems
• Valorization of agro-industrial waste through solid-state fermentation

Profile

Dr. Sergio Huerta Ochoa holds a Ph.D. in Biochemical Engineering from the University of Reading (United Kingdom, 1993), a Master’s degree in Chemical Engineering from the Universidad Autónoma Metropolitana Unidad Iztapalapa (1984), and a Bachelor’s degree in Chemical Engineering from the Universidad Veracruzana (1979). He completed a sabbatical fellowship as an Honorary Research Associate in the Department of Biochemical Engineering at University College London (United Kingdom, 2007–2008). He holds the highest rank of National Researcher Level III in the Sistema Nacional de Investigadoras e Investigadores (SNII) and is an elected member of the Mexican Academy of Sciences (AMC) and the Mexican Society of Biotechnology and Bioengineering (SMBB).

He serves as a Full-Time Professor in the Department of Biotechnology within the Division of Biological and Health Sciences at the Universidad Autónoma Metropolitana Unidad Iztapalapa, where he has been a faculty member for 44 years and received the 2017 Teaching Award.

His research focuses on whole-cell bioconversion process engineering in partition and solid/gas bioreactors. He has served as principal investigator on three CONAHCYT projects covering lactone biosynthesis, scale-down strategies, and citrus flavone bioconversion. He has co-authored 73 peer-reviewed articles in international journals (h-index 22, Scopus), 23 book chapters, and edited four textbooks (two published by Elsevier and two by UAM). He has supervised 14 master's theses and 10 doctoral dissertations —winning prestigious accolades including the Alfredo Sánchez Marroquín Award (2015) and the Durango State Science, Technology, and Innovation Award (2018)— and has served on the Editorial Board of the Biochemical Engineering Journal (Elsevier) since 2017.



Information provided by the academic staff

Research interests

• Design and optimization of biotransformation bioprocesses
• Biocatalysis in organic synthesis using whole cells
• Biocatalysis in solid/gas systems
• Valorization of agro-industrial waste through solid-state fermentation

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
Gómez-Ramos, G.A., Prado-Barragán, L.A., Huerta-Ochoa, S. and 3 more (...) (2026).Transient heat and mass transfer in a wall-cooled packed-tray bioreactor for solid-state fermentation: An engineering framework for parameter estimation. Biochemical Engineering Journal,228
OABuenrostro-Figueroa, J.J., Huerta-Ochoa, S., Aguilar, C.N. and 3 more (...) (2026).Green Enzyme Innovation: Improved Laundry Detergent Protease Production Through Solid-State Fermentation. Fermentation,12(4)
OAHernández-Alonso, J.U., Pichardo-Sánchez, M.A., Huerta-Ochoa, S. and 7 more (...) (2025).Impact of Co-Substrates on the Production of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Burkholderia thailandensis E264. Materials,18(15)
OAGómez-Ramos, G.A., Prado-Barragán, L.A., Rivera, B.A. and 5 more (...) (2025).Bioreactor Engineering for Circular Economy: Bioactive Compound Production in Solid-State Fermentation—Review. Chemical Engineering and Technology,48(1)
Dorantes-Landa, D.N., Hernandez-Aguirre, A., Ricardez-Sandoval, L. and 2 more (...) (2025).A systematic approach to defining a unit cell for fluid dynamics in packed beds with low tube-to-particle diameter ratio. AIChE Journal,71(4)
OACruz-Martínez, Y.A., Castillo-Araiza, C.O., Castillo-Rosales, E. and 2 more (...) (2025).Solid/Gas Synthesis of Isobutyl Propionate Catalyzed by Packed-Bed CalB Cross-Linked Enzyme Aggregates (CLEA). ACS Omega,10(48) 59692-59705| 9 |
Huerta-Ochoa, S., Prado-Barragán, L.A., Aguilar, C.N. (2025).Whole-Cell Biocatalysis: Fundamentals and Applications. Whole Cell Biocatalysis: Fundamentals and Applications,1-316| 7 |
Huerta-Ochoa, S., Prado-Barragán, L.A., Aguilar, C.N. (2025).Preface. Whole Cell Biocatalysis: Fundamentals and Applications,xix-xx
Huerta-Ochoa, S. (2025).Advantages and new potential applications of whole-cell biocatalysis. Whole Cell Biocatalysis: Fundamentals and Applications,1-19| 7 |
OABarrios-Nolasco, A., Castillo-Araiza, C.O., Huerta-Ochoa, S. and 3 more (...) (2024).Evaluating the Performance of Yarrowia lipolytica 2.2ab in Solid-State Fermentation under Bench-Scale Conditions in a Packed-Tray Bioreactor. Fermentation,10(7)
Cruz-Martínez, Y.A., Castillo-Araiza, C.O., Castillo-Rosales, E. and 1 more (...) (2024).Effect of adsorption/desorption of substrates/products during isobutyl propionate synthesis over CalB Immo Plus™ in solid/gas biocatalysis. Biochemical Engineering Journal,208| 9 |
Couder-García, M., Prado-Barragán, L.A., Huerta-Ochoa, S. and 1 more (...) (2024).Assessing the Impact of Transport Phenomena on Modeling and Optimization of Solid-State Fermentation for the Revalorization of Agro-Industrial Residues in a Wall‐Cooled Packed‐Bed Bioreactor. Chemical Engineering Research and Design,210365-381
Cordero-Soto, I.N., Huerta-Ochoa, S., Prado-Barragán, L.A. and 3 more (...) (2024).Food by-products potential use for flavor enhancers production. Enzymatic Processes for Food Valorization,129-143
OALondoño-Hernández, L., García-Gómez, M.D.J., Huerta-Ochoa, S. and 3 more (...) (2024).Effect of Glucose Concentration on the Production of Proteolytic Extract by Different Strains of Aspergillus under Solid-State Fermentation. Fermentation,10(2)
OAHernández-Guzmán, C., Hernández-Montiel, L.G., Velázquez-Lizarraga, A.E. and 6 more (...) (2024).Enhanced Antioxidant, Antifungal, and Herbicidal Activities through Bioconversion of Diosgenin by Yarrowia lipolytica P01a. Plants,13(18) | 2 |
OABuenrostro-Figueroa, J.J., Nevárez-Moorillón, G.V., Chávez-González, M.L. and 6 more (...) (2023).Improved Extraction of High Value-Added Polyphenols from Pomegranate Peel by Solid-State Fermentation. Fermentation,9(6)
Huerta-Ochoa, S., Castillo-Araiza, C.O., Cordero-Soto, I.N. and 3 more (...) (2023).Fundamentals and Applications of Solid/Gas Biocatalysis. Some Key Topics in Chemistry and Biochemistry for Biotechnologists,64-90
OAAmador-Mendoza, A., Juárez-Barrientos, J.M., Hernández-Hernández, H. and 4 more (...) (2022).EVALUATION OF COMBINED PROCESSES: CHITIN PURIFICATION FROM SHRIMP (Penaeus sp) AND GRASSHOPPER (Sphenarium purpurascens) EXOSKELETONS. Tropical and Subtropical Agroecosystems,25(3)
García-Martínez, L.E., Castillo-Araiza, C.O., Quijano, G. and 1 more (...) (2022).On the modelling and surface response analysis of a non-conventional wall-cooled solid/gas bioreactor with application in esterification. Chemical Engineering Journal,437
OACordero-Soto, I.N., Castillo-Araiza, C.O., Rutiaga-Quiñones, O.M. and 6 more (...) (2021).Intensification of 2-phenylethanol production using an aerated system assisted by a membrane-based solvent extraction technique. Revista Mexicana de Ingeniera Quimica,20(2) 739-750
Reyes-Cervantes, A., Robles-Morales, D.L., Téllez-Jurado, A. and 3 more (...) (2021).Evaluation in the performance of the biodegradation of herbicide diuron to high concentrations by Lysinibacillus fusiformis acclimatized by sequential batch culture. Journal of Environmental Management,291| 15 |
Hernández-Guzmán, C., Prado-Barragán, A., Gimeno, M. and 4 more (...) (2020).Whole-cell bioconversion of naringenin to high added value hydroxylated compounds using Yarrowia lipolytica 2.2ab in surface and liquid cultures. Bioprocess and Biosystems Engineering,43(7) 1219-1230
Cordero-Soto, I.N., Castillo-Araiza, C.O., García-Martínez, L.E. and 2 more (...) (2020).Solid/gas biocatalysis for aroma production: An alternative process of white biotechnology. Biochemical Engineering Journal,164| 3 | 9 |

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26I
Ingeniería EnzimáticaLicenciatura
2
26I
Seminario de Revisión Bibliográfica y Proyecto ExperimentalPosgrado
3
26I
EnzimologíaPosgrado
4
25O
Ingeniería EnzimáticaLicenciatura
5
25P
Ingeniería EnzimáticaLicenciatura
6
25P
Seminario de Examen PredoctoralPosgrado
7
25P
Seminario de Informe TerminalPosgrado
8
25I
Temas Selectos de Biotecnología IIPosgrado
9
25I
Temas Selectos de Biotecnología IPosgrado
10
25I
Seminario de Informe TerminalPosgrado
11
25I
Ingeniería EnzimáticaLicenciatura
12
24O
Ingeniería EnzimáticaLicenciatura
13
24O
Trabajo Experimental XIIPosgrado
14
24P
Ingeniería EnzimáticaLicenciatura
15
24P
Proyecto de Investigación IIILicenciatura
16
24P
Seminario de Informe TerminalPosgrado
17
24P
Trabajo Experimental XIPosgrado
18
24I
Trabajo Experimental XPosgrado
19
24I
Trabajo Experimental IIIPosgrado
20
24I
Trabajo Experimental IIIPosgrado
21
24I
Proyecto de Investigación IILicenciatura
22
24I
Ingeniería EnzimáticaLicenciatura
23
24I
EnzimologíaPosgrado
24
24I
Seminario de Examen PredoctoralPosgrado
25
23O
Ingeniería EnzimáticaLicenciatura
26
23O
Proyecto de Investigación ILicenciatura
27
23O
Proyecto de Investigación IPosgrado
28
23O
Trabajo Experimental IIPosgrado
29
23O
Trabajo Experimental IIPosgrado
30
23P
Trabajo Experimental IXPosgrado
31
23P
Trabajo Experimental IPosgrado
32
23P
Trabajo Experimental IPosgrado
33
23P
Seminario de Examen PredoctoralPosgrado
34
23P
Ingeniería EnzimáticaLicenciatura
35
23I
Ingeniería EnzimáticaLicenciatura
36
23I
Seminario de Examen PredoctoralPosgrado
37
23I
Seminario de Revisión Bibliográfica y Proyecto ExperimentalPosgrado
38
23I
Trabajo Experimental VIIIPosgrado
39
22O
Ingeniería EnzimáticaLicenciatura
40
22O
Investigación Doctoral IVPosgrado
41
22O
Trabajo Experimental VIIPosgrado
42
22P
Ingeniería EnzimáticaLicenciatura
43
22P
Trabajo Experimental IXPosgrado
44
22P
Trabajo Experimental VIPosgrado
45
22I
Ingeniería EnzimáticaLicenciatura
46
22I
Trabajo Experimental VPosgrado
47
22I
Trabajo Experimental VIIIPosgrado
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