Academic Work

• ORCID
• ResearchGate
• Scopus

Sustainable Development Goals

Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Profile

Professor Adriana Alarcón Aguilar has made her professional career in Experimental Biology in the three levels of academic training: Bachelor, Master's, and Ph.D. in Experimental Biology at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus.

Among her awards at UAM, she obtained the University Merit Medal in the Master's Degree in 2010 and Ph.D. in 2014 at the Iztapalapa Campus. She was the winner of the Research Award in 2016 in the area of Health Sciences with the article entitled "Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment".

She is a member of the National System of Researchers with Level I for the period 2020-2023 and is an Honorary Member of the Mexican Society of Biochemistry, A.C.

As a member of the organization of activities at the University she is Member of the Divisional Commission of Ethics of the Iztapalapa Campus; Member of the Academic Commission of Support to the Degree in Experimental Biology of the Iztapalapa Campus; Member of the Divisional Academic Commission of Biological and Health Sciences for the revision of the UEA Organic Chemistry of the Iztapalapa Campus; Member of the Organizing Commission of the Health Sciences Symposium, XXIII, XXIV and XXV; and Member of the Consolidated Academic Body of Bioenergetics and Cellular Aging of the Department of Health Sciences of the Iztapalapa Campus.

She currently directs the PRODEP project entitled: "Methotrexate as a hormone inducer to counteract oxidative damage in a cellular model of Parkinson's disease induced with MPTP". He also participates in the training of human resources at the undergraduate and graduate levels.

Her current lines of research are related to the molecular processes involved in Parkinson's disease. Mainly, in the investigation of the induction of the antioxidant hormone response in a model of astrocytes from rats of different ages. In addition, she studies the molecular processes related to the aging process, such as cellular senescence in different cell lines. In animal models, she participated in the study of sarcopenia and its relationship with obesity, as well as different physical and pharmacological treatments to delay its appearance in aging.

So far, she has published nine articles in indexed journals and one popularization article, as well as two chapters in international books.

Information provided by the academic staff

Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Academic Work

On the following pages you can consult the research work:

• ResearchGate

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• Scopus

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• ORCID

See publications

Some examples of publications

Select the bibliographic reference to consult each publication:

Open Access	References	UN SDGs
OA	Jiménez-Salazar, J., Garcia-Melo, L., Batina, N. and 5 more (...) (2025).Molecular Mechanisms of Estrogens in the Induction of Epithelial-to-Mesenchymal Transition and Metastasis in Breast Cancer. International Journal of Molecular Sciences,26(17)	\| 3 \|
OA	Flores-Torres, R.P., Salas-Venegas, V., Santín-Márquez, R. and 10 more (...) (2025).“Senotherapy as a multitarget intervention in chronic obesity: Modulation of senescence, neuroinflammation, dysbiosis, and synaptic integrity in middle-aged female Wistar rats”. Experimental Neurology,392	\| 3 \|
OA	López-Teros, M., Ávila-Galicia, K.E., Librado-Osorio, R. and 7 more (...) (2025).Palmitate-Induced Primary Rat Senescent Astrocytes Exhibit Higher Inflammatory Activity and a Distinct Transcriptomic Profile Compared to Reactive Astrocytes. Journal of Neurochemistry,169(7)
OA	Morales-Guzmán, A.S., Alarcón-Aguilar, A., Luna-López, A. and 5 more (...) (2025).Abnormal Homeostasis in the Redox State and Related Signaling Pathways, in Irritable Bowel Syndrome. Neurogastroenterology and Motility,37(12)
	Luna-López, A., Alarcón-Aguilar, A., Unzueta-Mendoza, J.J. and 2 more (...) (2024).Geroscience. Aging Research—Methodological Issues,51-59	\| 3 \|
	López-Teros, M., Alarcón-Aguilar, A., Castillo-Aragón, A. and 2 more (...) (2024).Cytokine profiling in senescent and reactive astrocytes: A systematic review. Neurobiology of Aging,13828-35
OA	Saldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,9	\| 4\| 10 \|
OA	Salas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,16	\| 3 \|
	López-Cervantes, S.P., Sánchez, N.S., Calahorra, M. and 10 more (...) (2022).Moderate exercise combined with metformin-treatment improves mitochondrial bioenergetics of the quadriceps muscle of old female Wistar rats. Archives of Gerontology and Geriatrics,102
	López-Teros, M., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2022).Contribution of senescent and reactive astrocytes on central nervous system inflammaging. Biogerontology,23(1) 21-33
OA	Luna-López, A., Flores-González, G.A., Rivera-Ruz, I.A. and 4 more (...) (2022).Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes. Dose-Response,20(3)
OA	Mena-Montes, B., Hernández-Álvarez, D., Pedraza-Vázquez, G. and 9 more (...) (2021).Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF-11. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
	Hernández-Arciga, U., Hernández-Álvarez, D., López-Cervantes, S.P. and 4 more (...) (2020).Effect of long-term moderate-exercise combined with metformin-treatment on antioxidant enzymes activity and expression in the gastrocnemius of old female Wistar rats. Biogerontology,21(6) 787-805
	Pedraza-Vázquez, G., Alarcón-Aguilar, A., Luna-López, A. (2020).Molecular biomarkers of aging studies in humans. Clinical Genetics and Genomics of Aging,111-123

Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.	Trim.	Course Name	Level
1	25O	Bioética	Licenciatura
2	25O	Trabajo Experimental I	Posgrado
3	25O	Trabajo Experimental I	Posgrado
4	25O	Trabajo Experimental I	Posgrado
5	25O	Trabajo Experimental III	Posgrado
6	25O	Trabajo Experimental III	Posgrado
7	25O	Trabajo de Investigación IV	Posgrado
8	25O	Trabajo de Investigación VI	Posgrado
9	25O	Trabajo de Investigación IX	Posgrado
10	25O	Seminario de Escritura de Tesis III	Posgrado
11	25O	Química General	Licenciatura
12	25P	Seminario de Escritura de Tesis II	Posgrado
13	25P	Trabajo de Investigación VIII	Posgrado
14	25P	Trabajo de Investigación V	Posgrado
15	25P	Trabajo de Investigación III	Posgrado
16	25P	Trabajo Experimental II	Posgrado
17	25P	Temas Selectos de Biología Experimental II	Posgrado
18	25P	Química General	Licenciatura
19	25P	Química Analítica	Licenciatura
20	25P	Trabajo Experimental II	Posgrado
21	25I	Trabajo de Investigación VII	Posgrado
22	25I	Seminario de Escritura de Tesis III	Posgrado
23	25I	Seminario de Escritura de Tesis I	Posgrado
24	25I	Trabajo de Investigación IV	Posgrado
25	25I	Trabajo de Investigación II	Posgrado
26	25I	Trabajo Experimental I	Posgrado
27	25I	Trabajo Experimental I	Posgrado
28	25I	Temas Selectos de Biología Experimental II	Licenciatura
29	25I	Química Analítica	Licenciatura
30	25I	Química General	Licenciatura
31	24O	Química General	Licenciatura
32	24O	Trabajo de Investigación I	Posgrado
33	24O	Trabajo de Investigación III	Posgrado
34	24O	Trabajo de Investigación VI	Posgrado
35	24O	Trabajo de Investigación IX	Posgrado
36	24O	Seminario de Escritura de Tesis II	Posgrado
37	24P	Seminario de Escritura de Tesis I	Posgrado
38	24P	Trabajo de Investigación VIII	Posgrado
39	24P	Trabajo de Investigación V	Posgrado
40	24P	Trabajo Experimental III	Posgrado
41	24P	Trabajo de Investigación II	Posgrado
42	24P	Formulación y Evaluación de Proyectos I	Licenciatura
43	24P	Química Analítica	Licenciatura
44	24I	Química General	Licenciatura
45	24I	Química Analítica	Licenciatura
46	24I	Temas Selectos de Biología Experimental II	Posgrado
47	24I	Trabajo Experimental II	Posgrado
48	24I	Trabajo de Investigación I	Posgrado
49	24I	Trabajo de Investigación IV	Posgrado
50	24I	Trabajo de Investigación VII	Posgrado
51	24I	Trabajo de Investigación IX	Posgrado
52	23O	Formulación y Evaluación de Proyectos I	Licenciatura
53	23O	Trabajo de Investigación VIII	Posgrado
54	23O	Trabajo de Investigación VI	Posgrado
55	23O	Trabajo de Investigación III	Posgrado
56	23O	Trabajo Experimental I	Posgrado
57	23O	Temas Selectos de Biología Experimental I	Posgrado
58	23O	Química General	Licenciatura
59	23P	Trabajo de Investigación VII	Posgrado
60	23P	Trabajo de Investigación V	Posgrado

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