Academic Work

• ORCID
• ResearchGate
• Scopus

Sustainable Development Goals

Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Profile

Professor Adriana Alarcón Aguilar has made her professional career in Experimental Biology in the three levels of academic training: Bachelor, Master's, and Ph.D. in Experimental Biology at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus.

Among her awards at UAM, she obtained the University Merit Medal in the Master's Degree in 2010 and Ph.D. in 2014 at the Iztapalapa Campus. She was the winner of the Research Award in 2016 in the area of Health Sciences with the article entitled "Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment".

She is a member of the National System of Researchers with Level I for the period 2020-2023 and is an Honorary Member of the Mexican Society of Biochemistry, A.C.

As a member of the organization of activities at the University she is Member of the Divisional Commission of Ethics of the Iztapalapa Campus; Member of the Academic Commission of Support to the Degree in Experimental Biology of the Iztapalapa Campus; Member of the Divisional Academic Commission of Biological and Health Sciences for the revision of the UEA Organic Chemistry of the Iztapalapa Campus; Member of the Organizing Commission of the Health Sciences Symposium, XXIII, XXIV and XXV; and Member of the Consolidated Academic Body of Bioenergetics and Cellular Aging of the Department of Health Sciences of the Iztapalapa Campus.

She currently directs the PRODEP project entitled: "Methotrexate as a hormone inducer to counteract oxidative damage in a cellular model of Parkinson's disease induced with MPTP". He also participates in the training of human resources at the undergraduate and graduate levels.

Her current lines of research are related to the molecular processes involved in Parkinson's disease. Mainly, in the investigation of the induction of the antioxidant hormone response in a model of astrocytes from rats of different ages. In addition, she studies the molecular processes related to the aging process, such as cellular senescence in different cell lines. In animal models, she participated in the study of sarcopenia and its relationship with obesity, as well as different physical and pharmacological treatments to delay its appearance in aging.

So far, she has published nine articles in indexed journals and one popularization article, as well as two chapters in international books.

Information provided by the academic staff

Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Academic Work

On the following pages you can consult the research work:

• ResearchGate

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• Scopus

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• ORCID

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Some examples of publications

Select the bibliographic reference to consult each publication:

Open Access	References	UN SDGs
OA	Ávila-Galicia, K.E., Alarcón-Aguilar, A., Soto-Reyes, E. and 1 more (...) (2026).Epigenetic remodeling induced by fatty acids: Chromatin modifications and cellular senescence during lipid overload. Ageing Research Reviews,118	\| 3 \|
OA	Flores-Torres, R.P., Salas-Venegas, V., Santín-Márquez, R. and 10 more (...) (2025).“Senotherapy as a multitarget intervention in chronic obesity: Modulation of senescence, neuroinflammation, dysbiosis, and synaptic integrity in middle-aged female Wistar rats”. Experimental Neurology,392	\| 3 \|
OA	López-Teros, M., Ávila-Galicia, K.E., Librado-Osorio, R. and 7 more (...) (2025).Palmitate-Induced Primary Rat Senescent Astrocytes Exhibit Higher Inflammatory Activity and a Distinct Transcriptomic Profile Compared to Reactive Astrocytes. Journal of Neurochemistry,169(7)
OA	Morales-Guzmán, A.S., Alarcón-Aguilar, A., Luna-López, A. and 5 more (...) (2025).Abnormal Homeostasis in the Redox State and Related Signaling Pathways, in Irritable Bowel Syndrome. Neurogastroenterology and Motility,37(12)
OA	Jiménez-Salazar, J., Garcia-Melo, L., Batina, N. and 5 more (...) (2025).Molecular Mechanisms of Estrogens in the Induction of Epithelial-to-Mesenchymal Transition and Metastasis in Breast Cancer. International Journal of Molecular Sciences,26(17)	\| 3 \|
OA	Saldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,9	\| 4 \| 10 \|
	López-Teros, M., Alarcón-Aguilar, A., Castillo-Aragón, A. and 2 more (...) (2024).Cytokine profiling in senescent and reactive astrocytes: A systematic review. Neurobiology of Aging,13828-35
	Luna-López, A., Alarcón-Aguilar, A., Unzueta-Mendoza, J.J. and 2 more (...) (2024).Geroscience. Aging Research—Methodological Issues,51-59	\| 3 \|
	López-Cervantes, S.P., Sánchez, N.S., Calahorra, M. and 10 more (...) (2022).Moderate exercise combined with metformin-treatment improves mitochondrial bioenergetics of the quadriceps muscle of old female Wistar rats. Archives of Gerontology and Geriatrics,102
OA	Salas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,16	\| 3 \|
OA	Luna-López, A., Flores-González, G.A., Rivera-Ruz, I.A. and 4 more (...) (2022).Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes. Dose-Response,20(3)
	López-Teros, M., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2022).Contribution of senescent and reactive astrocytes on central nervous system inflammaging. Biogerontology,23(1) 21-33
OA	Mena-Montes, B., Hernández-Álvarez, D., Pedraza-Vázquez, G. and 9 more (...) (2021).Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF-11. Oxidative Medicine and Cellular Longevity,2021	\| 3 \|
	Hernández-Arciga, U., Hernández-Álvarez, D., López-Cervantes, S.P. and 4 more (...) (2020).Effect of long-term moderate-exercise combined with metformin-treatment on antioxidant enzymes activity and expression in the gastrocnemius of old female Wistar rats. Biogerontology,21(6) 787-805
	Pedraza-Vázquez, G., Alarcón-Aguilar, A., Luna-López, A. (2020).Molecular biomarkers of aging studies in humans. Clinical Genetics and Genomics of Aging,111-123

Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.	Trim.	Course Name	Level
1	26I	Química Analítica	Licenciatura
2	26I	Seminario de Escritura de Tesis I	Posgrado
3	26I	Temas Selectos de Biología Experimental II	Posgrado
4	26I	Temas Selectos de Biología Experimental II	Posgrado
5	26I	Trabajo de Investigación V	Posgrado
6	26I	Trabajo de Investigación VII	Posgrado
7	26I	Trabajo Experimental II	Posgrado
8	26I	Trabajo Experimental II	Posgrado
9	26I	Trabajo Experimental II	Posgrado
10	26I	Bioética	Licenciatura
11	25O	Trabajo de Investigación IV	Posgrado
12	25O	Trabajo Experimental III	Posgrado
13	25O	Trabajo Experimental III	Posgrado
14	25O	Trabajo Experimental I	Posgrado
15	25O	Trabajo Experimental I	Posgrado
16	25O	Trabajo Experimental I	Posgrado
17	25O	Trabajo de Investigación VI	Posgrado
18	25O	Trabajo de Investigación IX	Posgrado
19	25O	Seminario de Escritura de Tesis III	Posgrado
20	25O	Química General	Licenciatura
21	25O	Bioética	Licenciatura
22	25P	Trabajo de Investigación III	Posgrado
23	25P	Trabajo Experimental II	Posgrado
24	25P	Trabajo Experimental II	Posgrado
25	25P	Trabajo de Investigación VIII	Posgrado
26	25P	Trabajo de Investigación V	Posgrado
27	25P	Temas Selectos de Biología Experimental II	Posgrado
28	25P	Seminario de Escritura de Tesis II	Posgrado
29	25P	Química General	Licenciatura
30	25P	Química Analítica	Licenciatura
31	25I	Trabajo Experimental I	Posgrado
32	25I	Trabajo Experimental I	Posgrado
33	25I	Trabajo de Investigación VII	Posgrado
34	25I	Trabajo de Investigación IV	Posgrado
35	25I	Trabajo de Investigación II	Posgrado
36	25I	Temas Selectos de Biología Experimental II	Licenciatura
37	25I	Seminario de Escritura de Tesis III	Posgrado
38	25I	Seminario de Escritura de Tesis I	Posgrado
39	25I	Química General	Licenciatura
40	25I	Química Analítica	Licenciatura
41	24O	Química General	Licenciatura
42	24O	Seminario de Escritura de Tesis II	Posgrado
43	24O	Trabajo de Investigación I	Posgrado
44	24O	Trabajo de Investigación III	Posgrado
45	24O	Trabajo de Investigación IX	Posgrado
46	24O	Trabajo de Investigación VI	Posgrado
47	24P	Química Analítica	Licenciatura
48	24P	Trabajo Experimental III	Posgrado
49	24P	Trabajo de Investigación VIII	Posgrado
50	24P	Trabajo de Investigación V	Posgrado
51	24P	Seminario de Escritura de Tesis I	Posgrado
52	24P	Formulación y Evaluación de Proyectos I	Licenciatura
53	24P	Trabajo de Investigación II	Posgrado
54	24I	Trabajo Experimental II	Posgrado
55	24I	Trabajo de Investigación VII	Posgrado
56	24I	Trabajo de Investigación IX	Posgrado
57	24I	Trabajo de Investigación IV	Posgrado
58	24I	Trabajo de Investigación I	Posgrado
59	24I	Temas Selectos de Biología Experimental II	Posgrado
60	24I	Química General	Licenciatura

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