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Perfil investigador
Esp
Dr. Adriana Alarcón Aguilar

Professor
Departament of Health Sciences

Division of Biological and Health Sciences


Level 1
Member of the National System of Researchers
(SNII)

Medicine and Health Sciences



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being

• 4 Quality Education


Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Profile

Professor Adriana Alarcón Aguilar has made her professional career in Experimental Biology in the three levels of academic training: Bachelor, Master's, and Ph.D. in Experimental Biology at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus.

Among her awards at UAM, she obtained the University Merit Medal in the Master's Degree in 2010 and Ph.D. in 2014 at the Iztapalapa Campus. She was the winner of the Research Award in 2016 in the area of Health Sciences with the article entitled "Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment".

She is a member of the National System of Researchers with Level I for the period 2020-2023 and is an Honorary Member of the Mexican Society of Biochemistry, A.C.

As a member of the organization of activities at the University she is Member of the Divisional Commission of Ethics of the Iztapalapa Campus; Member of the Academic Commission of Support to the Degree in Experimental Biology of the Iztapalapa Campus; Member of the Divisional Academic Commission of Biological and Health Sciences for the revision of the UEA Organic Chemistry of the Iztapalapa Campus; Member of the Organizing Commission of the Health Sciences Symposium, XXIII, XXIV and XXV; and Member of the Consolidated Academic Body of Bioenergetics and Cellular Aging of the Department of Health Sciences of the Iztapalapa Campus.

She currently directs the PRODEP project entitled: "Methotrexate as a hormone inducer to counteract oxidative damage in a cellular model of Parkinson's disease induced with MPTP". He also participates in the training of human resources at the undergraduate and graduate levels.

Her current lines of research are related to the molecular processes involved in Parkinson's disease. Mainly, in the investigation of the induction of the antioxidant hormone response in a model of astrocytes from rats of different ages. In addition, she studies the molecular processes related to the aging process, such as cellular senescence in different cell lines. In animal models, she participated in the study of sarcopenia and its relationship with obesity, as well as different physical and pharmacological treatments to delay its appearance in aging.

So far, she has published nine articles in indexed journals and one popularization article, as well as two chapters in international books.



Information provided by the academic staff

Research interests

• Neurodegenerative Diseases
• Hormesis
• Oxidative Stress
• Sarcopenia
• Senescence

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAÁvila-Galicia, K.E., Alarcón-Aguilar, A., Soto-Reyes, E. and 1 more (...) (2026).Epigenetic remodeling induced by fatty acids: Chromatin modifications and cellular senescence during lipid overload. Ageing Research Reviews,1183
OAFlores-Torres, R.P., Salas-Venegas, V., Santín-Márquez, R. and 10 more (...) (2025).“Senotherapy as a multitarget intervention in chronic obesity: Modulation of senescence, neuroinflammation, dysbiosis, and synaptic integrity in middle-aged female Wistar rats”. Experimental Neurology,3923
OALópez-Teros, M., Ávila-Galicia, K.E., Librado-Osorio, R. and 7 more (...) (2025).Palmitate-Induced Primary Rat Senescent Astrocytes Exhibit Higher Inflammatory Activity and a Distinct Transcriptomic Profile Compared to Reactive Astrocytes. Journal of Neurochemistry,169(7)
OAMorales-Guzmán, A.S., Alarcón-Aguilar, A., Luna-López, A. and 5 more (...) (2025).Abnormal Homeostasis in the Redox State and Related Signaling Pathways, in Irritable Bowel Syndrome. Neurogastroenterology and Motility,37(12)
OAJiménez-Salazar, J., Garcia-Melo, L., Batina, N. and 5 more (...) (2025).Molecular Mechanisms of Estrogens in the Induction of Epithelial-to-Mesenchymal Transition and Metastasis in Breast Cancer. International Journal of Molecular Sciences,26(17) 3
López-Teros, M., Alarcón-Aguilar, A., Castillo-Aragón, A. and 2 more (...) (2024).Cytokine profiling in senescent and reactive astrocytes: A systematic review. Neurobiology of Aging,13828-35
Luna-López, A., Alarcón-Aguilar, A., Unzueta-Mendoza, J.J. and 2 more (...) (2024).Geroscience. Aging Research—Methodological Issues,51-593
OASaldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,94|10
López-Cervantes, S.P., Sánchez, N.S., Calahorra, M. and 10 more (...) (2022).Moderate exercise combined with metformin-treatment improves mitochondrial bioenergetics of the quadriceps muscle of old female Wistar rats. Archives of Gerontology and Geriatrics,102
López-Teros, M., Alarcón-Aguilar, A., López-Diazguerrero, N.E. and 2 more (...) (2022).Contribution of senescent and reactive astrocytes on central nervous system inflammaging. Biogerontology,23(1) 21-33
OASalas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,163
OALuna-López, A., Flores-González, G.A., Rivera-Ruz, I.A. and 4 more (...) (2022).Methotrexate Induces an Antioxidant Hormetic Response in Primary Rat Astrocytes. Dose-Response,20(3)
OAMena-Montes, B., Hernández-Álvarez, D., Pedraza-Vázquez, G. and 9 more (...) (2021).Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and Oxidative Stress and Increasing GDF-11. Oxidative Medicine and Cellular Longevity,20213
Hernández-Arciga, U., Hernández-Álvarez, D., López-Cervantes, S.P. and 4 more (...) (2020).Effect of long-term moderate-exercise combined with metformin-treatment on antioxidant enzymes activity and expression in the gastrocnemius of old female Wistar rats. Biogerontology,21(6) 787-805
Pedraza-Vázquez, G., Alarcón-Aguilar, A., Luna-López, A. (2020).Molecular biomarkers of aging studies in humans. Clinical Genetics and Genomics of Aging,111-123

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26P
Química GeneralLicenciatura
2
26P
Química AnalíticaLicenciatura
3
26P
Trabajo de Investigación IPosgrado
4
26P
Trabajo Experimental IIIPosgrado
5
26P
Trabajo Experimental IIIPosgrado
6
26P
Trabajo Experimental IIIPosgrado
7
26P
Trabajo de Investigación VIPosgrado
8
26P
Trabajo de Investigación VIIIPosgrado
9
26P
Seminario de Escritura de Tesis IIPosgrado
10
26I
BioéticaLicenciatura
11
26I
Química AnalíticaLicenciatura
12
26I
Seminario de Escritura de Tesis IPosgrado
13
26I
Temas Selectos de Biología Experimental IIPosgrado
14
26I
Temas Selectos de Biología Experimental IIPosgrado
15
26I
Trabajo de Investigación VPosgrado
16
26I
Trabajo de Investigación VIIPosgrado
17
26I
Trabajo Experimental IIPosgrado
18
26I
Trabajo Experimental IIPosgrado
19
26I
Trabajo Experimental IIPosgrado
20
25O
BioéticaLicenciatura
21
25O
Química GeneralLicenciatura
22
25O
Seminario de Escritura de Tesis IIIPosgrado
23
25O
Trabajo de Investigación IVPosgrado
24
25O
Trabajo de Investigación IXPosgrado
25
25O
Trabajo de Investigación VIPosgrado
26
25O
Trabajo Experimental IPosgrado
27
25O
Trabajo Experimental IPosgrado
28
25O
Trabajo Experimental IPosgrado
29
25O
Trabajo Experimental IIIPosgrado
30
25O
Trabajo Experimental IIIPosgrado
31
25P
Química AnalíticaLicenciatura
32
25P
Química GeneralLicenciatura
33
25P
Seminario de Escritura de Tesis IIPosgrado
34
25P
Temas Selectos de Biología Experimental IIPosgrado
35
25P
Trabajo de Investigación IIIPosgrado
36
25P
Trabajo de Investigación VPosgrado
37
25P
Trabajo de Investigación VIIIPosgrado
38
25P
Trabajo Experimental IIPosgrado
39
25P
Trabajo Experimental IIPosgrado
40
25I
Química AnalíticaLicenciatura
41
25I
Química GeneralLicenciatura
42
25I
Seminario de Escritura de Tesis IPosgrado
43
25I
Seminario de Escritura de Tesis IIIPosgrado
44
25I
Temas Selectos de Biología Experimental IILicenciatura
45
25I
Trabajo de Investigación IIPosgrado
46
25I
Trabajo de Investigación IVPosgrado
47
25I
Trabajo de Investigación VIIPosgrado
48
25I
Trabajo Experimental IPosgrado
49
25I
Trabajo Experimental IPosgrado
50
24O
Química GeneralLicenciatura
51
24O
Seminario de Escritura de Tesis IIPosgrado
52
24O
Trabajo de Investigación IPosgrado
53
24O
Trabajo de Investigación IIIPosgrado
54
24O
Trabajo de Investigación IXPosgrado
55
24O
Trabajo de Investigación VIPosgrado
56
24P
Formulación y Evaluación de Proyectos ILicenciatura
57
24P
Química AnalíticaLicenciatura
58
24P
Seminario de Escritura de Tesis IPosgrado
59
24P
Trabajo de Investigación IIPosgrado
60
24P
Trabajo de Investigación VPosgrado
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