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Perfil investigador
Esp
Dr. Gerardo Jorge Félix Martínez

Professor
Departament of Electrical Engineering

Division of Basic Sciences and Engineering


Level 1
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sites of interest

• biofisica.izt

Sustainable Development Goals

• 3 Good Health and Well-Being

• 4 Quality Education

• 5 Gender Equality


Research interests

• Pancreatic islet architectures
• Electrical activity of excitable cells
• Glucolipotoxicity in pancreatic beta-cells
• Computational modeling of physiological systems

Profile

Dr. Gerardo Jorge Félix Martínez holds a Bachelor’s degree in Physics from the Autonomous University of Zacatecas and a Ph.D. in Science, with a specialization in Biomedical Engineering, from the Universidad Autónoma Metropolitana (UAM). He completed a postdoctoral stay at the Department of Applied Mathematics and Computer Science at the University of Cantabria. He received the UAM University Merit Medal and served as a Researcher for Mexico at SECIHTI from 2017 to 2025. He currently works as a Full Professor C in the Department of Electrical Engineering at the Universidad Autónoma Metropolitana and has belonged to the National System of Researchers since 2017, currently at Level 1.

His research focuses on the study of pancreatic cells and islets of Langerhans to analyze their function in health and disease, with an emphasis on type 1 and type 2 diabetes, from a biophysical perspective that combines computational and experimental approaches. He developed DiabetesID, an application designed to support the early detection of undiagnosed diabetes in the Mexican adult population through non-invasive methods.

He has published more than thirty works, including research articles, reviews, and conference papers, on the mathematical and computational modeling of physiological systems. His research develops simulation and analysis tools to study cell and islet dynamics, calcium signaling, ion channel activity, and the reconstruction, architecture, and viability of islets under different oxygen, glucose, and vascularization conditions.

He currently serves as technical lead of the Basic and Frontier Science project “Functional implications of the impact of type 2 diabetes on the architecture of pancreatic islets using computational models,” with funding for the 2024–2026 period.



Information provided by the academic staff

Research interests

• Pancreatic islet architectures
• Electrical activity of excitable cells
• Glucolipotoxicity in pancreatic beta-cells
• Computational modeling of physiological systems

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAFélix-Martínez, G.J., de la Cruz, L., Whisman, D. and 1 more (...) (2025).Impact of vascular density on pancreatic islet viability: a computational study. Frontiers in Physiology,16
Félix-Martínez, G.J., Osorio-Londoño, D., Godínez-Fernández, J.R. (2025).Computational Study on the Viability of Encapsulated Pancreatic Islets for Type 1 Diabetes. IFMBE Proceedings,121123-130| 3 |
Pimentel-Granados, K.G., Godínez-Fernández, J.R., Félix-Martínez, G.J. (2025).Identification of Short and Long-Term Correlations in Simulated Single-Channel Currents Using Nonlinear Analysis. IFMBE Proceedings,121222-228
OAMillan-Pacheco, C., Serratos, I.N., Félix-Martínez, G.J. and 3 more (...) (2025).Cholesterol Concentration in Cell Membranes and its Impact on Receptor–Ligand Interaction: A Computational Study of ATP-Sensitive Potassium Channels and ATP Binding. Journal of Membrane Biology,258(3) 225-236| 3 |
OAFélix-Martínez, G.J., Osorio-Londoño, D., Godínez-Fernández, J.R. (2024).Impact of oxygen and glucose availability on the viability and connectivity of islet cells: A computational study of reconstructed avascular human islets. PLoS Computational Biology,20(8)
Félix-Martínez, G.J., Picones, A., Godínez-Fernández, J.R. (2024).Short and long-range correlations in single-channel currents from inwardly rectifying K+ channels. Chaos, Solitons and Fractals,178
OAFélix-Martínez, G.J., Godínez-Fernández, J.R. (2023).A primer on modelling pancreatic islets: from models of coupled β-cells to multicellular islet models. Islets,15(1) | 3 |
Flores-Santillán, D.A., Godínez-Fernández, J.R., Félix-Martínez, G.J. (2023).Effects of Blood Flow on Insulin Concentration: A Modelling Study. IFMBE Proceedings,86219-224
Ruiz-Santiago, S., Godínez-Fernández, J.R., Félix-Martínez, G.J. (2023).Simulating the Loss of β -cell Mass in a Human Pancreatic Islet: Structural and Functional Implications. IFMBE Proceedings,86204-211| 3 |
Valverde-Alonzo, C.A., Félix-Martínez, G.J., González-Velez, V. and 1 more (...) (2023).Role of Endogenous Ca 2 + Buffering and the Readily Releasable Pool on Fast Secretion in Auditory Inner Hair Cells. IFMBE Proceedings,86212-218
Félix-Martínez, G.J., Nicolás-Mata, A., Godínez-Fernández, J.R. (2022).Computational Reconstruction of Pancreatic Islets as a Tool for Structural and Functional Analysis. Journal of Visualized Experiments,2022(181)
OAFélix-Martínez, G.J., Godínez-Fernández, J.R. (2022).Comparative analysis of reconstructed architectures from mice and human islets. Islets,14(1) 23-35
OAFélix-Martínez, G.J. (2022).IsletLab: an application to reconstruct and analyze islet architectures. Islets,14(1) 36-39
Juayerk-Herrera, K.L., Félix-Martínez, G.J., Picones, A. and 2 more (...) (2021).Deterministic modeling of single-channel and whole-cell currents. Journal of Theoretical Biology,508
Félix-Martínez, G.J., González-Vélez, V., Godínez-Fernández, J.R. and 1 more (...) (2020).Electrophysiological models of the human pancreatic δ-cell: From single channels to the firing of action potentials. International Journal for Numerical Methods in Biomedical Engineering,36(2)
OAFélix-Martínez, G.J., N. Mata, A., Godínez-Fernández, J.R. (2020).Reconstructing human pancreatic islet architectures using computational optimization. Islets,12(6) 121-133
Félix-Martínez, G.J., Godínez-Fernández, J.R. (2020).Effect of cell size on insulin secretion in human β-cells: a simulation study. Health and Technology,10(2) 379-383| 3 |
Félix-Martínez, G.J., Godínez-Fernández, J.R. (2020).Comparative analysis of screening models for undiagnosed diabetes in Mexico. Endocrinologia, Diabetes y Nutricion,67(5) 333-341| 3 |

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

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Universidad Autónoma Metropolitana, 2026.