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Perfil investigador
Esp
Dr. Elena Aréchaga Ocampo

Professor
Departament of Natural Sciences

Division of Natural Sciences and Engineering


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Cuajimalpa Campus

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Academic Group



Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Identification and functional analysis of microRNAs in cancer
• MicroRNAs in cancer therapy
• Cancer transcriptomics
• Bioinformatics
• Cell and molecular biology

Profile

Professor Elena Arechaga Ocampo is a biologist graduated from the School of Biological Sciences of the Universidad Autónoma del Estado de Morelos. She did her undergraduate thesis at the Nitrogen Fixation Research Center (currently CCG) of the Universidad Nacional Autónoma de México (UNAM), where she worked on aspects of plant molecular biology. Subsequently, she completed her Master´s and Ph.D. in Molecular Biomedicine at CINVESTAV, working on the study of the expression and function of apoptotic proteins in cervical-uterine cancer.

From 2008 to 2014, she was an Associate Researcher at the National Cancer Institute, working initially in clinical research focused on the response to antineoplastic treatments in lung cancer. Based on her observations, she initiated a line of research based on the use of genomic and molecular biology tools to study the expression and function of microRNAs in tumor cells resistant to radiotherapy.

Since January 2014 she is a Professor at the Department of Natural Sciences of the Universidad Autónoma Metropolitana (UAM) Cuajimalpa Campus.

At the University, she continues working in her research line and teaches the courses of General Microbiology, Introduction to Molecular Biology, Biochemistry I, Cell Biology, Cell Biology II, Molecular Biology Techniques I, II, III, and Selected Topics. In the Graduate Program in Natural Sciences and Engineering (PCNI), she teaches Molecular Biology and Selected Topics UEAs.

She has trained two undergraduate students, six Master's students, and two Ph.D. students. She has been an advisor of 12 Master´s students and nine Ph.D. students.

She has published 24 original articles, three review articles, eight book chapters, three popular science articles, two laboratory manuals, and the edition of one book.

She has participated in several national and international congresses.

She has organized the 1st National Symposium on Oncogenomics and Cancer Proteomics and the First Conference on Neuroscience in the framework of the Brain Week 2018; supported by the Mexico City Chapter of the Society for Neuroscience (CDMX-SFN). He belongs to the National System of Researchers Level I, has PRODEP Profile and is a member of the Academic Body of Cell and Tissue Physiology of the Division of Natural Sciences and Engineering (DCNI).



Information provided by the academic staff

Research interests

• Identification and functional analysis of microRNAs in cancer
• MicroRNAs in cancer therapy
• Cancer transcriptomics
• Bioinformatics
• Cell and molecular biology

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:




Academic Group

Consult the information provided by the Academic Group




Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
Arechaga-Ocampo, E. (2024).Epigenetics as a determinant of radiation response in cancer. International Review of Cell and Molecular Biology,383145-190| 3 |
OAÁlvarez-Hilario, L.G., Salmerón-Bárcenas, E.G., Ávila-López, P.A. and 10 more (...) (2023).Circulating miRNAs as Noninvasive Biomarkers for PDAC Diagnosis and Prognosis in Mexico. International Journal of Molecular Sciences,24(20) | 3 |
Flores Fortis, M., Perez Añorve, I.X., del Moral Hernandez, O. and 2 more (...) (2023).Transcriptomic profiles-based approach to decode the role of miR-122 in triple negative breast cancer. Genes Chromosomes and Cancer,62(7) 392-404| 3 |
OAGarcía-Andrade, F., Vigueras-Villaseñor, R.M., Chávez-Saldaña, M.D. and 7 more (...) (2023).Molecular Characterization of Patients with Cryptorchidism: Preliminary Search for an Expression Profile Related to That of Testicular Germ-Cell Tumors. Diagnostics,13(18) | 3 |
OAMadrigal, T., Ortega-Bernal, D., Herrera, L.A. and 4 more (...) (2023).Mutant p53 Gain-of-Function Induces Migration and Invasion through Overexpression of miR-182-5p in Cancer Cells. Cells,12(20) | 3 |
OAGarcía-Andrade, F., Vigueras-Villaseñor, R.M., Chávez-Saldaña, M.D. and 5 more (...) (2022).The Role of microRNAs in the Gonocyte Theory as Target of Malignancy: Looking for Potential Diagnostic Biomarkers. International Journal of Molecular Sciences,23(18) | 3 |
OAPerez-Bacho, E.G., Beltrán-Anaya, F.O., Arechaga-Ocampo, E. and 5 more (...) (2022).The E6 Oncoprotein of HPV16 AA-c Variant Regulates Cell Migration through the MINCR/miR-28-5p/RAP1B Axis. Viruses,14(5) | 3 |
Landero-Huerta, D.A., Vigueras-Villaseñor, R.M., Taja-Chayeb, L. and 6 more (...) (2021).Analysis of the CAG tract length in the Androgen Receptor gene in Mexican patients with nonsyndromic cryptorchidism. Journal of Pediatric Endocrinology and Metabolism,34(7) 843-849
Cabrera-Licona, A., Pérez-Añorve, I.X., Flores-Fortis, M. and 5 more (...) (2021).Deciphering the epigenetic network in cancer radioresistance. Radiotherapy and Oncology,15948-59| 3 |
OALandero-Huerta, D.A., Vigueras-Villaseñor, R.M., Yokoyama-Rebollar, E. and 7 more (...) (2020).Cryptorchidism and Testicular Tumor: Comprehensive Analysis of Common Clinical Features and Search of SNVs in the KIT and AR Genes. Frontiers in Cell and Developmental Biology,8| 3 |
OAPatiño-Morales, C.C., Soto-Reyes, E., Arechaga-Ocampo, E. and 4 more (...) (2020).Curcumin stabilizes p53 by interaction with NAD(P)H:quinone oxidoreductase 1 in tumor-derived cell lines. Redox Biology,28| 3 |
OAPerez-Añorve, I.X., Gonzalez-De la Rosa, C.H., Soto-Reyes, E. and 10 more (...) (2019).New insights into radioresistance in breast cancer identify a dual function of miR-122 as a tumor suppressor and oncomiR. Molecular Oncology,13(5) 1249-1267| 3 |
OASalgado-Albarrán, M., González-Barrios, R., Guerra-Calderas, L. and 10 more (...) (2019).The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer. Oncogenesis,8(8) | 3 |
Vaisman, C.E., Del Moral-Hernandez, O., Moreno-Campuzano, S. and 7 more (...) (2018).C33-A cells transfected with E6*I or E6*II the short forms of HPV-16 E6, displayed opposite effects on cisplatin-induced apoptosis. Virus Research,24794-101| 3 |
Peña-Mercado, E., Garcia-Lorenzana, M., Arechaga-Ocampo, E. and 2 more (...) (2018).Evaluation of HIF-1α and iNOS in ischemia/ reperfusion gastric model: Bioimpedance, histological and immunohistochemical analyses. Histology and Histopathology,33(8) 815-823
OAOrtega-Bernal, D., GONZÁLEZ-DE LA ROSA, C.H., Arechaga-Ocampo, E. and 3 more (...) (2018).A meta-analysis of transcriptome datasets characterizes malignant transformation from melanocytes and nevi to melanoma. Oncology Letters,16(2) 1899-1911| 3 |
Landero-Huerta, D.A., Vigueras-Villasenor, R.M., Yokoyama-Rebollar, E. and 4 more (...) (2017).Epigenetic and risk factors of testicular germ cell tumors: A brief review. Frontiers in Bioscience - Landmark,22(7) 1073-1098| 3 |
OAArechaga-Ocampo, E., Lopez-Camarillo, C., Villegas-Sepulveda, N. and 12 more (...) (2017).Tumor suppressor miR-29c regulates radioresistance in lung cancer cells. Tumor Biology,39(3) | 3 |
Flores-Pérez, A., Marchat, L.A., Sánchez, L.L. and 9 more (...) (2016).Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy. Proteomics - Clinical Applications,10(2) 172-182| 3 |
OAMedina-Aguilar, R., Marchat, L.A., Ocampo, E.A. and 5 more (...) (2016).Resveratrol inhibits cell cycle progression by targeting Aurora kinase A and Polo-like kinase 1 in breast cancer cells. Oncology Reports,35(6) 3696-3704| 3 |
OAFlores-Pérez, A., Marchat, L.A., Rodríguez-Cuevas, S. and 12 more (...) (2016).Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer. Scientific Reports,6| 3 |
Pena-Mercado, E., Garcia-Lorenzana, M., Arechaga, E. and 2 more (...) (2016).Gastric mucosa injury quantification in an ischemia - Reperfusion experimental model. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS,2016-2303-2306
OAQuintero Barceinas, R.S., García-Regalado, A., Aréchaga-Ocampo, E. and 2 more (...) (2015).All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism. BioMed Research International,2015| 3 |
Martínez-Salazar, M., López-Urrutia, E., Arechaga-Ocampo, E. and 10 more (...) (2014).Biochemical and proteomic analysis of spliceosome factors interacting with intron-1 of human papillomavirus type-16. Journal of Proteomics,111184-197| 3 |
Arechaga-Ocampo, E., Diaz-Chavez, J., Lopez-Camarillo, C. and 5 more (...) (2013).MicroRNAs in lung cancer: From genomics to clinical applications. MicroRNAs in Cancer,220-251| 3 |
OAGarcía-Regalado, A., Vargas, M., García-Carrancá, A. and 2 more (...) (2013).Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells. Molecular Cancer,12(1) | 3 |

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Courses offered

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
23O
Seminario IPosgrado
2
23O
Trabajo Experimental IPosgrado
3
23O
Seminario VIPosgrado
4
23O
Seminario VIPosgrado
5
23O
Trabajo de Investigación VIPosgrado
6
23O
Trabajo de Investigación VIPosgrado
7
23O
Introducción a la Biología MolecularLicenciatura
8
23O
Proyecto Terminal IILicenciatura
9
23O
Biología CelularLicenciatura
10
23P
Proyecto de Investigación Doctoral XIIPosgrado
11
23P
Seminario VPosgrado
12
23P
Seminario VPosgrado
13
23P
Trabajo de Investigación VPosgrado
14
23P
Trabajo de Investigación VPosgrado
15
23P
Técnicas de Biología Molecular IIILicenciatura
16
23P
Proyecto Terminal ILicenciatura
17
23I
Proyecto de Investigación Doctoral XIPosgrado
18
23I
Seminario IVPosgrado
19
23I
Seminario IVPosgrado
20
23I
Trabajo de Investigación IVPosgrado
21
23I
Trabajo de Investigación IVPosgrado
22
23I
Biología Molecular Genómica Posgrado
23
23I
Temas Selectos en Biomedicina Molecular ILicenciatura
24
23I
Temas Selectos en Biomedicina Molecular IILicenciatura
25
23I
Temas Selectos IPosgrado
26
22O
Técnicas de Biología Molecular ILicenciatura
27
22O
Biología CelularLicenciatura
28
22O
Proyecto de Investigación Doctoral XPosgrado
29
22O
Seminario IIIPosgrado
30
22O
Seminario IIIPosgrado
31
22O
Trabajo de Investigación IIIPosgrado
32
22O
Trabajo de Investigación IIIPosgrado
33
22O
Trabajo de Redacción de Tesis IIPosgrado
34
22P
Técnicas de Biología Molecular IIILicenciatura
35
22P
Seminario Doctoral IVPosgrado
36
22P
Proyecto de Investigación Doctoral IXPosgrado
37
22P
Seminario IIPosgrado
38
22P
Seminario IIPosgrado
39
22P
Trabajo de Investigación IIPosgrado
40
22P
Trabajo de Investigación IIPosgrado
41
22P
Trabajo de Redacción de Tesis IPosgrado
42
22I
Temas Selectos en Biomedicina Molecular ILicenciatura
43
22I
Temas Selectos en Biomedicina Molecular IILicenciatura
44
22I
Proyecto de Investigación Doctoral VIIIPosgrado
45
22I
Seminario IPosgrado
46
22I
Seminario IPosgrado
47
22I
Trabajo de Investigación IPosgrado
48
22I
Trabajo de Investigación IPosgrado
49
22I
Trabajo de Investigación IXPosgrado
50
22I
Seminario VIIPosgrado
51
21O
Técnicas de Biología Molecular ILicenciatura
52
21O
Biología CelularLicenciatura
53
21O
Proyecto de Investigación IIIPosgrado
54
21O
Proyecto de Investigación Doctoral VIIPosgrado
55
21O
Trabajo de Investigación VIIIPosgrado
56
21P
Técnicas de Biología Molecular IIILicenciatura
57
21P
Proyecto de Investigación IIPosgrado
58
21P
Biología MolecularPosgrado
59
21P
Seminario Doctoral IIIPosgrado
60
21P
Proyecto de Investigación Doctoral VIPosgrado
Information provided by the Dirección de Sistemas Escolares
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Universidad Autónoma Metropolitana, 2024.