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Perfil investigador
Esp
Dr. Beatriz Gómez González

Professor
Departament of Reproductive Biology

Division of Biological and Health Sciences


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Neuroscience
• Blood-brain barrier
• Blood-testes barrier
• Neuro-immuno-endocrinology
• Sleep

Profile

Professor Beatriz Gómez González studied for her Ph.D. in Psychology, in the Field of Behavioral Neurosciences at the Faculty of Psychology of the Universidad Nacional Autónoma de México, UNAM (2005-2009). Her thesis was entitled "Effect of prenatal or postnatal stress on the development of the blood-brain barrier in the rat (Rattus norvegicus)". Tutor: Dr. Alfonso Escobar. Graduated in Psychology from the Faculty of Psychology, UNAM (2000-2003) with the thesis "Brain dysgenesis and behavioral deficits in an experimental animal model of stress". (Honorable Mention). Tutor: Dr. Alfonso Escobar.

She is the author of 21 articles published in indexed journals of international circulation, author of two international book chapters, and editor of a specialized volume of a journal of global circulation. Dr. Gómez has an h-index of nine and more than 300 citations to her published works. She has contributed to the formation of high-level human resources, and has trained three doctoral level students, five master's level students, and five bachelor's level students. Every year Dr. Gómez participates in the Organizing Committee of the International Brain Week at the Iztapalapa Campus and participates with a stand in the Science Fair of the same institution. Dr. Gómez's research projects have allowed her to understand the mechanisms of sleep regulation on the functioning of biological barriers, with particular emphasis on neuroimmunoendocrine interactions.

Her research topics include the following: Neuroimmunoendocrine consequences of sleep loss; Regulation of the blood-brain barrier dependent on the wake/sleep cycle; and Regulation of the blood-testicular barrier dependent on the wake/sleep cycle.

Methodologies:
1 - Isolation of cerebral microvasculature.
2 - Techniques to evaluate the permeability of the blood-brain barrier to circulating molecules in the blood.
3 - Surgery to implant electrodes to record EEG and EMG activity in rats.
4 - Polysomnographic recording in experimental animals.
5 - Tissue processing for transmission electron microscopy.
6 - Obtaining and quantitative analysis of images obtained with transmission electron microscopy.
7 - Western blotting.
8 - Experimental microsurgery for endocrine gland removal.
9 - Immunohistochemistry.
10 - Classical histological techniques to study the nervous system.
11 - Behavioral tests in experimental animals.



Information provided by the academic staff

Research interests

• Neuroscience
• Blood-brain barrier
• Blood-testes barrier
• Neuro-immuno-endocrinology
• Sleep

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OASantín-Márquez, R., Salas-Venegas, V., Garcia-Álvarez, J.A. and 5 more (...) (2025).Sex differences in middle-aged and old Wistar rats in response to long-term sulforaphane treatment for prevention of neuroinflammation, cognitive decline and brain senescence. Biogerontology,26(3)
OAAvilez-Avilez, J.J., García-Aviles, J.E., Ramírez-Carreto, R.J. and 6 more (...) (2025).Progressive Blood–Brain Barrier Disruption in Sleep-Restricted Young Mice: Cellular Senescence and Neuroinflammation Crosstalk. Neurochemical Research,50(5)
OAGarcía-Aviles, J.E., Avilez-Avilez, J.J., Sánchez-Hernández, J. and 11 more (...) (2025).A Sleeping Opportunity Does Not Restore Hippocampal Alterations Induced by 10 Days of Sleep Restriction in Rats. Neurochemical Research,50(5)
OAFlores-Torres, R.P., Salas-Venegas, V., Santín-Márquez, R. and 10 more (...) (2025).“Senotherapy as a multitarget intervention in chronic obesity: Modulation of senescence, neuroinflammation, dysbiosis, and synaptic integrity in middle-aged female Wistar rats”. Experimental Neurology,392| 3 |
OASaldívar-Garduño, A., Alarcón-Aguilar, A., Cervantes-Ríos, E. and 4 more (...) (2024).Gender equity in university students in Mexico City, after 20 months of remote classes during the COVID-19 pandemic. Frontiers in Education,9| 4| 10 |
Avilez-Avilez, J.J., Medina-Flores, M.F., Gómez-Gonzalez, B. (2024).Sleep loss impairs blood-brain barrier function: Cellular and molecular mechanisms. Vitamins and Hormones,12677-96
Ramírez-Cruz, A., Gómez-González, B., Baiza-Gutman, L.A. and 7 more (...) (2023).Nicotinamide, an acetylcholinesterase uncompetitive inhibitor, protects the blood‒brain barrier and improves cognitive function in rats fed a hypercaloric diet. European Journal of Pharmacology,959
OAMedina-Flores, F., Hurtado-Alvarado, G., Deli, M.A. and 1 more (...) (2023).The Active Role of Pericytes During Neuroinflammation in the Adult Brain. Cellular and Molecular Neurobiology,43(2) 525-541
OASotelo-Ramírez, C.E., Camarena, B., Sanabrais-Jiménez, M.A. and 4 more (...) (2023).Toll-Like Receptor (TLR) 1, 2, and 6 Gene Polymorphisms Support Evidence of Innate Immune Factors in Schizophrenia. Neuropsychiatric Disease and Treatment,192353-2361
Santín-Márquez, R., Hernández-Arciga, U., Salas-Venegas, V. and 7 more (...) (2022).Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals. Biogerontology,23(5) 587-613
OAGómez-González, B., Hurtado-Alvarado, G., Velázquez-Moctezuma, J. (2022).Editorial: Beyond the borders: The gates and fences of neuroimmune interaction, volume II. Frontiers in Integrative Neuroscience,16| 3 |
OASalas-Venegas, V., Flores-Torres, R.P., Rodríguez-Cortés, Y.M. and 9 more (...) (2022).The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience,16| 3 |
OASantín-Márquez, R., Ramírez-Cordero, B., Toledo-Pérez, R. and 12 more (...) (2021).Sensory and memory processing in old female and male Wistar rat brain, and its relationship with the cortical and hippocampal redox state. GeroScience,43(4) 1899-1920
Medina-Flores, F., Hurtado-Alvarado, G., Gómez-González, B. (2021).Selective Regional Isolation of Brain Microvessels. Methods in Molecular Biology,236737-46
Domínguez-Salazar, E., Hurtado-Alvarado, G., Medina-Flores, F. and 5 more (...) (2020).Chronic sleep loss disrupts blood–testis and blood–epididymis barriers, and reduces male fertility. Journal of Sleep Research,29(3)
OAMedina-Flores, F., Hurtado-Alvarado, G., Contis-Montes de Oca, A. and 4 more (...) (2020).Sleep loss disrupts pericyte-brain endothelial cell interactions impairing blood-brain barrier function. Brain, Behavior, and Immunity,89118-132
OAViñuela-Berni, V., Gómez-González, B., Quintanar-Stephano, A. (2020).Blockade of Arginine Vasopressin receptors prevents blood-brain barrier breakdown in Experimental Autoimmune Encephalomyelitis. Scientific Reports,10(1)

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
Trabajo de Redacción de Tesis IPosgrado
2
25O
Seminario de Escritura de Tesis IPosgrado
3
25P
Seminario VIIPosgrado
4
25P
Trabajo de Investigación IXPosgrado
5
25P
Seminario de Escritura de Tesis IIIPosgrado
6
25P
Trabajo de Investigación IXPosgrado
7
25I
Trabajo de Investigación VIIIPosgrado
8
25I
Seminario de Escritura de Tesis IIPosgrado
9
25I
Seminario de Escritura de Tesis IIIPosgrado
10
25I
Trabajo de Investigación VIIIPosgrado
11
24O
Trabajo de Investigación VIIPosgrado
12
24O
Seminario de Escritura de Tesis IIPosgrado
13
24O
Seminario de Escritura de Tesis IPosgrado
14
24O
Trabajo de Investigación VIIPosgrado
15
24O
Trabajo Experimental IPosgrado
16
24P
Trabajo de Investigación VIPosgrado
17
24P
Trabajo de Investigación IXPosgrado
18
24P
Seminario de Escritura de Tesis IPosgrado
19
24P
Seminario de Escritura de Tesis IIIPosgrado
20
24P
Seminario Doctoral IIPosgrado
21
24P
Seminario VIPosgrado
22
24P
Trabajo de Investigación VIPosgrado
23
24I
Proyecto de Investigación IIILicenciatura
24
24I
Proyecto de Investigación Doctoral IIPosgrado
25
24I
Trabajo de Investigación VPosgrado
26
24I
Seminario VPosgrado
27
24I
Trabajo de Investigación IXPosgrado
28
24I
Trabajo de Investigación VPosgrado
29
24I
Seminario de Escritura de Tesis IIPosgrado
30
23O
Trabajo de Investigación VIIIPosgrado
31
23O
Proyecto de Investigación Doctoral IPosgrado
32
23O
Seminario de Escritura de Tesis IPosgrado
33
23O
Trabajo de Investigación VIIIPosgrado
34
23O
Trabajo de Investigación IVPosgrado
35
23O
Trabajo de Investigación IVPosgrado
36
23O
Seminario IVPosgrado
37
23O
Proyecto de Investigación IILicenciatura
38
23O
Taller de Biometría Agropecuaria ILicenciatura
39
23P
Seminario de Escritura de Tesis IIIPosgrado
40
23P
Seminario de Escritura de Tesis IIIPosgrado
41
23P
Trabajo de Investigación IXPosgrado
42
23P
Trabajo de Investigación VIIPosgrado
43
23P
Trabajo de Investigación VIIPosgrado
44
23P
Trabajo de Investigación IIIPosgrado
45
23P
Trabajo de Investigación IIIPosgrado
46
23P
Ritmos Biológicos y CulturasLicenciatura
47
23P
Proyecto de Investigación IIILicenciatura
48
23P
Seminario IIIPosgrado
49
23P
Proyecto de Investigación ILicenciatura
50
23I
Seminario de Escritura de Tesis IIPosgrado
51
23I
Trabajo de Investigación IIPosgrado
52
23I
Seminario IIPosgrado
53
23I
Seminario de Escritura de Tesis IIPosgrado
54
23I
Trabajo de Investigación VIIIPosgrado
55
23I
Trabajo de Investigación VIPosgrado
56
23I
Trabajo de Investigación VIPosgrado
57
23I
Trabajo de Investigación IIPosgrado
58
23I
Método ExperimentalPosgrado
59
23I
Proyecto de Investigación IILicenciatura
60
23I
Ritmos Biológicos y CulturasLicenciatura
Information provided by the Dirección de Sistemas Escolares
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Universidad Autónoma Metropolitana, 2025.