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Perfil investigador
Esp
Dr. Luis Enrique Gómez Quiroz

Professor
Departament of Health Sciences

Division of Biological and Health Sciences


Level 3
Member of the National System of Researchers
(SNII)

Medicine and Health Sciences



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Liver and pancreas cancer
• Biology and pathobiology of the pancreas and liver
• oxidative stress
• signal transduction
• Functional genomics

Profile

Luis Enrique Gómez Quiroz is a Professor in the Department of Health Sciences at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus, where he also serves as coordinator of Graduate Studies of the Division of Biological and Health Sciences. He is a graduate in Experimental Biology (master's and doctorate), studies that earned him the medal for university merit at both levels.

Subsequently, he did his postdoctorate at the National Cancer Institute (NCI) of the National Institutes of Health of the United States (NIH); his work was related to the cellular, molecular and genomic mechanisms of the onset and progression of hepatocellular carcinoma, a field in which he continues to develop, in addition to this, other lines of research in which he works are the control of gene expression by changes in the cellular redox state controlled by HGF and c-Met, and in general the mechanisms of damage and repair of liver diseases, using from cellular models in vitro, genomic, to preclinical in animals and clinical approaches in patients.

He has directed several doctoral, master's, and bachelor's theses. He has received several national and international awards.

He is a member of: National System of Researchers (SNI) at its highest level (SNI-III); the Mexican Academy of Sciences, the National Academy of Medicine of Mexico, -the International Liver Cancer Association (ILCA); Mexican Academy of Sciences; among other national and international scientific associations.

He has published more than 130 papers, most of them international, including original articles, review articles, books, and book chapters, among others. He has been an evaluator of the best doctoral theses at CINVESTAV (Arturo Rosemblueth Award), a member of the Awards Committee of the Mexican Academy of Sciences, and of the awards granted by the Mexican Foundation for Liver Health, among others.

He has taught and lectured at higher education institutions and research centers in Mexico and abroad, including Hanyang University, Seoul, South Korea, Johannes Gutenberg University, Mainz, Germany, Rennes University, France, National Cancer Institute/National Institutes of Health (NCI/NIH), Bethesda MD, USA. He has lectured at various conferences, symposia, and meetings in Egypt, Spain, Japan, France, USA, Italy, and Germany, among others.

He collaborates with institutions in the United States, Germany, France, Spain, Brazil, Argentina, and Korea in the field of liver cancer and cellular redox state biology.



Information provided by the academic staff

Research interests

• Liver and pancreas cancer
• Biology and pathobiology of the pancreas and liver
• oxidative stress
• signal transduction
• Functional genomics

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAGomez-Quiroz, L.E., Seo, D., Lee, Y.-H. and 9 more (...) (2026).Corrigendum to “Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress” [Toxicology 361–362 (2016) 39–48, (S0300483X16301214), (10.1016/j.tox.2016.07.004)]. Toxicology,520
OAEscobedo-Calvario, A., Chávez-Rodríguez, L., Souza-Arroyo, V. and 8 more (...) (2025).Growth differentiation factor 11 modulates metabolism, mitigating the pro-tumoral behavior provided by M2-like macrophages in hepatocellular carcinoma-derived cells. World Journal of Gastroenterology,31(40) | 3 |
OASánchez-Rodríguez, M., Lazzarini-Lechuga, R., Souza-Arroyo, V. and 8 more (...) (2025).GDF11 downregulates FOXP3 in T-cell acute lymphoblastic leukemia-derived cells and associates with restraining aggressiveness. Oncology Research,33(8) 2075-2084| 3 |
OARosales-Muñoz, G.J., Souza-Arroyo, V., Bucio-Ortiz, L. and 3 more (...) (2025).Acute pancreatitis experimental models, advantages and disadvantages. Journal of Physiology and Biochemistry,81(3) 539-556
OARosales-Muñoz, G.J., Souza-Arroyo, V., Bucio-Ortiz, L. and 3 more (...) (2025).Correction: Acute pancreatitis experimental models, advantages and disadvantages (Journal of Physiology and Biochemistry, (2025), 81, 3, (539-556), 10.1007/s13105-025-01091-w). Journal of Physiology and Biochemistry,81(3) 831-832| 3 |
OAHerrera-Martell, M., Mejía, A., Gómez-Quiroz, L.E. and 1 more (...) (2025).Aspergillus terreus AtfB (bZIP) differently regulates lovastatin production in submerged fermentation and in solid-state fermentation. Bioscience, Biotechnology and Biochemistry,89(8) 1227-1235
OAMontoya-Gress, L., Juárez-Rojas, L., Almanza-Pérez, J. and 7 more (...) (2024).Changes in D4 and GABAA subunit α3 receptors in the thalamic reticular nucleus caused by unilateral lesion of the globus pallidus. Acta Neurobiologiae Experimentalis,84(3) 275-287
OAPérez-Aguilar, B., Marquardt, J.U., Muñoz-Delgado, E. and 4 more (...) (2023).Changes in the Acetylcholinesterase Enzymatic Activity in Tumor Development and Progression. Cancers,15(18) | 3 |
Gerardo-Ramírez, M., German-Ramirez, N., Escobedo-Calvario, A. and 6 more (...) (2023).The hepatic effects of GDF11 on health and disease. Biochimie,208129-140| 3 |
Pedraza-Vázquez, G., Mena-Montes, B., Hernández-Álvarez, D. and 6 more (...) (2023).A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation. Archives of Gerontology and Geriatrics,105| 3 |
Palestino-Domínguez, M., Escobedo-Calvario, A., Salas-Silva, S. and 7 more (...) (2023).Erk1/2 signaling mediates the HGF-induced protection against ethanol and acetaldehyde-induced toxicity in the pancreatic RINm5F cell line. Journal of Biochemical and Molecular Toxicology,37(4)
Salas-Silva, S., López-Ramirez, J., Barrera-Chimal, J. and 9 more (...) (2022).Hepatocyte growth factor reverses cholemic nephropathy associated with α-naphthylisothiocyanate-induced cholestasis in mice. Life Sciences,295
OAMartinez-Armenta, C., Suarez-Ahedo, C., Olivos-Meza, A. and 7 more (...) (2022).The Critical Role of Hypoxia in the Re-Differentiation of Human Articular Chondrocytes. Cells,11(16)
OAQuevedo-Ocampo, J., Escobedo-Calvario, A., Souza-Arroyo, V. and 5 more (...) (2022).Folate Metabolism in Hepatocellular Carcinoma. What Do We Know So Far?. Technology in Cancer Research and Treatment,21| 3 |
Souza-Arroyo, V., Fabián, J.J., Bucio-Ortiz, L. and 3 more (...) (2022).The mechanism of the cadmium-induced toxicity and cellular response in the liver. Toxicology,480| 3 |
OAGomez-Quiroz, L.E., Roman, S. (2022).Influence of genetic and environmental risk factors in the development of hepatocellular carcinoma in Mexico. Annals of Hepatology,27| 3 |
Hernandez, S., Simoni-Nieves, A., Gerardo-Ramírez, M. and 14 more (...) (2021).GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cells. Journal of Cellular Physiology,236(5) 4076-4090| 3 |
OASalas-Silva, S., Simoni-Nieves, A., Chávez-Rodríguez, L. and 3 more (...) (2021).Mechanism of cholangiocellular damage and repair during cholestasis. Annals of Hepatology,26| 3 |
OAGil-Hernández, A., Arroyo-Campuzano, M., Simoni-Nieves, A. and 3 more (...) (2021).Relevance of Membrane Contact Sites in Cancer Progression. Frontiers in Cell and Developmental Biology,8| 3 |
OAMartinez-Armenta, C., Camacho-Rea, M.C., Martínez-Nava, G.A. and 4 more (...) (2021).Therapeutic Potential of Bioactive Compounds in Honey for Treating Osteoarthritis. Frontiers in Pharmacology,12
OAChávez-Rodríguez, L., Escobedo-Calvario, A., Salas-Silva, S. and 5 more (...) (2021).Fructose Consumption and Hepatocellular Carcinoma Promotion. Livers,1(4) 250-262| 3 |
OASimoni-Nieves, A., Clavijo-Cornejo, D., Salas-Silva, S. and 6 more (...) (2021).HGF/c-Met regulates p22phox subunit of the NADPH oxidase complex in primary mouse hepatocytes by transcriptional and post-translational mechanisms. Annals of Hepatology,25
Miranda-Nuñez, J.E., Zamilpa-Alvarez, A., Fortis-Barrera, A. and 7 more (...) (2021).GLUT4 translocation in C2C12 myoblasts and primary mouse hepatocytes by an antihyperglycemic flavone from Tillandsia usneoides. Phytomedicine,89| 3 |
OASimoni-Nieves, A., Salas-Silva, S., Chávez-Rodríguez, L. and 10 more (...) (2021).The consumption of cholesterol-enriched diets conditions the development of a subtype of hcc with high aggressiveness and poor prognosis. Cancers,13(7) | 3 |
OASalas-Silva, S., Simoni-Nieves, A., Razori, M.V. and 10 more (...) (2020).HGF induces protective effects in α-naphthylisothiocyanate-induced intrahepatic cholestasis by counteracting oxidative stress. Biochemical Pharmacology,174
Bello-Monroy, O., Mata-Espinosa, D., Enríquez-Cortina, C. and 10 more (...) (2020).Hepatocyte growth factor enhances the clearance of a multidrug-resistant Mycobacterium tuberculosis strain by high doses of conventional chemotherapy, preserving liver function. Journal of Cellular Physiology,235(2) 1637-1648| 3 |
OAPosadas-Rodríguez, P., Posadas-Rodríguez, N.E., González-Puertos, V.Y. and 6 more (...) (2020).TBHQ Induces a Hormetic Response That Protects L6 Myoblasts against the Toxic Effect of Palmitate. Oxidative Medicine and Cellular Longevity,2020| 3 |
OALópez-Reyes, A., Martinez-Armenta, C., Espinosa-Velázquez, R. and 5 more (...) (2020).NLRP3 Inflammasome: The Stormy Link Between Obesity and COVID-19. Frontiers in Immunology,11| 3 |
Retana-Márquez, S., Juárez-Rojas, L., Ávila-Quintero, A. and 5 more (...) (2020).Neuroendocrine disruption is associated to infertility in chronically stressed female rats. Reproductive Biology,20(4) 474-483
Mora-Ramiro, B., Jiménez-Estrada, M., Zentella-Dehesa, A. and 5 more (...) (2020).Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. Journal of Natural Products,83(8) 2447-2455| 3 | 9 |
Vergara-Mendoza, M., Gomez-Quiroz, L.E., Miranda-Labra, R.U. and 5 more (...) (2020).Regulation of Cas9 by viral proteins Tat and Rev for HIV-1 inactivation. Antiviral Research,180| 3 |
OACastellanos-Tapia, L., Tejero-Barrera, M.E., Salas-Silva, S. and 3 more (...) (2020).Mediterranean-like mix of fatty acids induces cellular protection on lipid-overloaded hepatocytes from western diet fed mice. Annals of Hepatology,19(5) 489-496
OAJacobo-Herrera, N., Gomez-Quiroz, L., Pérez-Plasencia, C. (2020).Editorial: Tumor Cell Metabolism and Autophagy as Therapeutic Targets. Frontiers in Oncology,10| 3 |

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26I
Seminario de Escritura de Tesis IIPosgrado
2
26I
Proyecto de Investigación IIILicenciatura
3
26I
Trabajo Experimental IIPosgrado
4
26I
Trabajo Experimental IIPosgrado
5
26I
Trabajo de Investigación VPosgrado
6
26I
Temas Selectos de Biología Experimental IIPosgrado
7
26I
Temas Selectos de Biología Experimental IIPosgrado
8
26I
Seminario VPosgrado
9
26I
Trabajo de Investigación VPosgrado
10
25O
Biología Celular del CáncerLicenciatura
11
25O
Proyecto de Investigación IILicenciatura
12
25O
Seminario de Escritura de Tesis IPosgrado
13
25O
Seminario de Escritura de Tesis IIIPosgrado
14
25O
Seminario IVPosgrado
15
25O
Temas Selectos de Biología Experimental IPosgrado
16
25O
Temas Selectos de Biología Experimental IIIPosgrado
17
25O
Temas Selectos de Biología Experimental IIIPosgrado
18
25O
Trabajo de Investigación IVPosgrado
19
25O
Trabajo de Investigación IVPosgrado
20
25O
Trabajo Experimental IPosgrado
21
25O
Trabajo Experimental IPosgrado
22
25O
Trabajo Experimental IIIPosgrado
23
25O
Trabajo Experimental IIIPosgrado
24
25P
Trabajo Experimental IIIPosgrado
25
25P
Trabajo Experimental IIPosgrado
26
25P
Trabajo Experimental IIPosgrado
27
25P
Trabajo de Investigación IXPosgrado
28
25P
Trabajo de Investigación IIIPosgrado
29
25P
Temas Selectos de Biología Experimental IIIPosgrado
30
25P
Temas Selectos de Biología Experimental IIIPosgrado
31
25P
Temas Selectos de Biología Experimental IIPosgrado
32
25P
Temas Selectos de Biología Experimental IIPosgrado
33
25P
Seminario IIIPosgrado
34
25P
Seminario de Escritura de Tesis IIPosgrado
35
25P
Proyecto de Investigación ILicenciatura
36
25P
Introducción a la Investigación IILicenciatura
37
25P
Biología Celular del CáncerLicenciatura
38
25P
Temas Selectos de Biología Experimental IIIPosgrado
39
25I
Temas Selectos de Biología Experimental IIPosgrado
40
25I
Trabajo Experimental IIPosgrado
41
25I
Trabajo Experimental IPosgrado
42
25I
Trabajo Experimental IPosgrado
43
25I
Trabajo de Investigación VIIIPosgrado
44
25I
Trabajo de Investigación IIPosgrado
45
25I
Trabajo de Investigación IIPosgrado
46
25I
Temas Selectos de Biología Experimental IIPosgrado
47
25I
Temas Selectos de Biología Experimental IIPosgrado
48
25I
Temas Selectos de Biología Experimental IIPosgrado
49
25I
Temas Selectos de Biología Experimental IIPosgrado
50
25I
Método ExperimentalPosgrado
51
25I
Patología MolecularLicenciatura
52
25I
Seminario de Escritura de Tesis IPosgrado
53
25I
Seminario IIPosgrado
54
25I
Temas Selectos de Biología Experimental IPosgrado
55
25I
Temas Selectos de Biología Experimental IPosgrado
56
25I
Temas Selectos de Biología Experimental IIPosgrado
57
25I
Temas Selectos de Biología Experimental IPosgrado
58
24O
Trabajo de Investigación IXPosgrado
59
24O
Trabajo de Investigación VIIPosgrado
60
24O
Seminario IPosgrado
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Universidad Autónoma Metropolitana, 2026.