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Perfil investigador
Esp
Dr. Francisco Javier Alarcón Aguilar

Professor
Departament of Health Sciences

Division of Biological and Health Sciences


Level 3
Member of the National System of Researchers
(SNII)

Medicine and Health Sciences



Iztapalapa Campus

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Sustainable Development Goals

• 2 Zero Hunger

• 3 Good Health and Well-Being

• 4 Quality Education


Research interests

• Pharmacologúy of Natural Products
• Phytochemistry of Natural Products
• Metabolic Sydrome
• Inflammation and Oxidative Stress
• Computer-Assisted Molecular Modeling

Profile

For the past 25 years, Dr. Francisco Javier Alarcón Aguilar has been involved with the Pharmacology research group at UAM in generating knowledge in the research line "Pharmacology of medicinal plants and diseases related to metabolic syndrome", conducting cutting-edge research in the field.

Within this group, his participation has been crucial for its development and evolution, with the aim of taking chemical-pharmacological research of natural products to a mechanistic level, delving into computer-assisted rational drug design, and, overall, implementing cutting-edge techniques to elucidate their molecular-level mechanisms of action. This has allowed the research group to be recognized as a benchmark in the investigation of natural resources with potential utility in the treatment of diseases related to metabolic syndrome, both nationally and internationally.

During this period, several achievements have been obtained, among which the following stand out: Research articles 103; Human resources 144 (41 undergraduate research projects, 53 social services, 1 specialization advisory in biotechnology, 16 co-supervisions of master's theses, and 18 doctoral theses; 10 master's thesis advisories and 3 doctoral thesis advisories); participation in specialized scientific events 425 (300 national and 125 international); evaluation committees 241 (137 research article reviews; 46 research project reviews (CONACYT, PNPC, etc.); 43 on examination or opposition jury committees); updating courses 10; awards 32; article citations, over 5000 until February 2024.

It is worth noting that all these achievements have been obtained thanks to a great effort on the part of all the members of the group. Currently, Dr. Alarcón Aguilar is the coordinator of the Academic Body in Pharmacology of Medicinal Plants.



Information provided by the academic staff

Research interests

• Pharmacologúy of Natural Products
• Phytochemistry of Natural Products
• Metabolic Sydrome
• Inflammation and Oxidative Stress
• Computer-Assisted Molecular Modeling

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAJuárez-Pérez, M.G., Alarcón-Aguilar, F.J., Jasso-Villagómez, J.I. and 4 more (...) (2026).Effect of a fructooligosaccharides fraction from Psacalium decompositum on the intestinal bacterial microbiota of rats. Bioscience of Microbiota, Food and Health,45(1) 1-8
Giacoman-Martínez, A., Almanza-Pérez, J., Alarcón-Aguilar, F. and 6 more (...) (2026).New hypoglycemic effects of indorenate mediated by the 5-HT1a and 5-HT2a receptors: in vivo and in silico studies. Canadian journal of physiology and pharmacology,1041-12
OASuárez-Alonso, A., Giacoman-Martínez, A., Alarcon-Villaseñor, E.F. and 2 more (...) (2025).UAM-Ixachi: Desktop Tool for Massive Automated Molecular Docking. Journal of the Mexican Chemical Society,69(1) 1-23
Estrella-Parra, E.A., Avila-Acevedo, J.G., García-Bores, A.M. and 4 more (...) (2025).Intoxication Associated with Ayahuasca Consumption, Characterization, and Comparative Analysis of the Beverage's Components: A Case Report. Revista Colombiana de Psiquiatria,54(2) 350-357
OAAlarcon-Aguilar, F.J., Rosiles-Alanis, R.W., Blancas-Flores, G. and 6 more (...) (2025).Cucurbita ficifolia regulates the secretomes of adipocytes and macrophages in co-culture, breaking meta-inflammation. Advances in Traditional Medicine,25(3) 709-721| 3 |
OAArietta-García, A.G., Calzada, F., Franco-Vadillo, A. and 6 more (...) (2025).The Antitumor Role of Incomptine A in a Breast Cancer Murine Model: Impairment of Hexokinase II Expression and Apoptosis Induction. Cells,14(15) | 3 |
OAAlarcón-Aguilar, F.J., Almanza-Pérez, J.C., Blancas-Flores, G. and 4 more (...) (2024).Evolution of research in the Pharmacology Laboratory at the Universidad Autónoma Metropolitana-Iztapalapa: A Historical Review. Journal of the Mexican Chemical Society,68(4) 685-716
OAOrtiz-Barragán, E., Estrada-Soto, S., Giacoman-Martínez, A. and 7 more (...) (2024).Antihyperglycemic and Hypolipidemic Activities of Flavonoids Isolated from Smilax Dominguensis Mediated by Peroxisome Proliferator-Activated Receptors. Pharmaceuticals,17(11) | 3 |
OAOrtega, R., Calzada, F., Fortis-Barrera, Á. and 2 more (...) (2024).Ethnobotanical Medica, Pharmacology and Phytochemistry of the Species Salvia del Valle de México: A Review. Journal of the Mexican Chemical Society,68(4) 774-832| 3 |
Alarcón-Aguilar, F.J., de la Mora, I.D., Fortis-Barrera, A. (2024).Anti-inflammatory action and effects on carbohydrate and lipid metabolism: an understudied role of interleukin-6. European Cytokine Network,35(4) 48-55| 3 |
Lázaro-Suárez, M.L., Domínguez De La Mora, I., Rodríguez-Aguilar, J.C. and 6 more (...) (2023).Role of Perivascular Adipose Tissue in Aorta Reactivity from Obese and Hyperglycemic CD-1 Mice: New Insights into Perivascular Adipose Tissue. Metabolic Syndrome and Related Disorders,21(2) 101-108| 3 |
OABarrón-Álvarez, N., Prado-Barragán, L.A., Fortis-Barrera, M.D.L.Á. and 1 more (...) (2022).Fermentation of the Cucurbita ficifolia Fruit Juice: Its Antioxidant Activity and Effects on the Glycemia. Beverages,8(3)
OAMontoya-Alatriste, C.A., Alarcon-Aguilar, F.J. (2022).Cannabis and cannabinoids as an alternative remedy in metabolic syndrome. Brazilian Journal of Pharmaceutical Sciences,58| 3 |
OAOrtega, R., Valdés, M., Alarcón-Aguilar, F.J. and 4 more (...) (2022).Antihyperglycemic Effects of Salvia polystachya Cav. and Its Terpenoids: α-Glucosidase and SGLT1 Inhibitors. Plants,11(5) | 3 |
OADel Carmen Juárez-Vázquez, M., Zamilpa A, A., León-Díaz, R. and 6 more (...) (2021).Phytochemical screening and anti-inflammatory potential of the organic extracts from cleoserrata serrata (Jacq.) iltis. Pharmacognosy Journal,13(5) 1225-1241
OAHernandez-Hernandez, A.B., Alarcon-Aguilar, F.J., Garcia-Lorenzana, M. and 2 more (...) (2021).Jatropha Neopauciflora Pax Latex Exhibits Wound-Healing Effect in Normal and Diabetic Mice. Journal of Evidence-Based Integrative Medicine,26| 3 |
Giacoman-Martínez, A., Alarcón-Aguilar, F.J., Zamilpa, A. and 4 more (...) (2021).α-Amyrin induces glut4 translocation mediated by AMPK and PPARδ/γ in c2c12 myoblasts. Canadian Journal of Physiology and Pharmacology,99(9) 935-942| 3 |
Romero-Nava, R., Alarcón-Aguilar, F.J., Giacoman-Martínez, A. and 7 more (...) (2021).Glycine is a competitive antagonist of the TNF receptor mediating the expression of inflammatory cytokines in 3T3-L1 adipocytes. Inflammation Research,70(5) 605-618| 3 |
Miranda-Nuñez, J.E., Zamilpa-Alvarez, A., Fortis-Barrera, A. and 7 more (...) (2021).GLUT4 translocation in C2C12 myoblasts and primary mouse hepatocytes by an antihyperglycemic flavone from Tillandsia usneoides. Phytomedicine,89| 3 |
Fortis-Barrera, M.D.L.Á., Alarcón-Aguilar, F.J., Becerril-García, A. and 6 more (...) (2020).Mechanism of the Hypoglycemic Activity and Hepatoprotective Effect of the Aqueous Extract of Cecropia obtusifolia Bertol. Journal of Medicinal Food,23(7) 783-792| 3 |
Mora-Ramiro, B., Jiménez-Estrada, M., Zentella-Dehesa, A. and 5 more (...) (2020).Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. Journal of Natural Products,83(8) 2447-2455| 3| 9 |
Loza-Rodríguez, H., Estrada-Soto, S., Alarcón-Aguilar, F.J. and 5 more (...) (2020).Oleanolic acid induces a dual agonist action on PPARγ/α and GLUT4 translocation: A pentacyclic triterpene for dyslipidemia and type 2 diabetes. European Journal of Pharmacology,883| 3 |

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
BiofisicoquímicaPosgrado
2
25O
Seminario VIPosgrado
3
25O
Trabajo de Investigación VIPosgrado
4
25O
Desarrollo de FármacosLicenciatura
5
25P
Seminario VPosgrado
6
25P
Trabajo de Investigación VPosgrado
7
25P
Trabajo Experimental IIIPosgrado
8
25I
Seminario de Escritura de Tesis IIIPosgrado
9
25I
Trabajo Experimental IIPosgrado
10
25I
Seminario IVPosgrado
11
25I
Trabajo de Investigación IVPosgrado
12
24O
Seminario IIIPosgrado
13
24O
Trabajo de Investigación IIIPosgrado
14
24O
Seminario de Revisión BibliográficaPosgrado
15
24O
Trabajo Experimental IPosgrado
16
24O
Seminario de Escritura de Tesis IIPosgrado
17
24O
Proyecto de Investigación IIILicenciatura
18
24P
Proyecto de Investigación IILicenciatura
19
24P
Seminario de Escritura de Tesis IPosgrado
20
24P
Seminario IIPosgrado
21
24P
Trabajo de Investigación IIPosgrado
22
24I
Proyecto de Investigación IIILicenciatura
23
24I
Proyecto de Investigación ILicenciatura
24
24I
Proyecto de Investigación IILicenciatura
25
24I
Proyecto de Investigación IIILicenciatura
26
24I
Seminario IPosgrado
27
24I
Trabajo de Investigación IPosgrado
28
24I
Trabajo de Investigación IXPosgrado
29
23O
Proyecto de Investigación IILicenciatura
30
23O
Trabajo de Investigación VIIIPosgrado
31
23O
Proyecto de Investigación IIILicenciatura
32
23O
Proyecto de Investigación IILicenciatura
33
23P
Principios de Farmacología y ToxicologíaLicenciatura
34
23P
Proyecto de Investigación ILicenciatura
35
23P
Proyecto de Investigación IILicenciatura
36
23P
Desarrollo de FármacosLicenciatura
37
23P
Proyecto de Investigación ILicenciatura
38
23P
Trabajo de Investigación VIIPosgrado
39
23P
Temas Selectos de Química InorgánicaPosgrado
40
23I
Principios de Farmacología y ToxicologíaLicenciatura
41
23I
Proyecto de Investigación ILicenciatura
42
23I
Proyecto de Investigación IIILicenciatura
43
23I
Trabajo de Investigación VIPosgrado
44
22O
Proyecto de Investigación ILicenciatura
45
22O
Trabajo de Investigación VPosgrado
46
22O
Desarrollo de FármacosLicenciatura
47
22O
Proyecto de Investigación IIILicenciatura
48
22O
Proyecto de Investigación IILicenciatura
49
22P
Principios de Farmacología y ToxicologíaLicenciatura
50
22P
Proyecto de Investigación ILicenciatura
51
22P
Proyecto de Investigación IILicenciatura
52
22P
Desarrollo de FármacosLicenciatura
53
22P
Trabajo de Investigación IVPosgrado
54
22I
Proyecto de Investigación ILicenciatura
55
22I
Principios de Farmacología y ToxicologíaLicenciatura
56
22I
Trabajo de Investigación IIIPosgrado
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Universidad Autónoma Metropolitana, 2025.