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Perfil investigador
Esp
Dr. María Elisa Drago Serrano

Professor
Departament of Biological Systems

Division of Biological and Health Sciences


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Xochimilco Campus

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Sustainable Development Goals

• 3 Good Health and Well-Being

• 4 Quality Education

• 8 Decent Work and Economic Growth


Research interests

• Intestinal Homeostasis
• Intestinal Barrier
• Bovine Lactoferrin
• Ulverative Colitis
• Stress

Profile

Dr. María Elisa Drago Serrano obtained her Bachelor’s degree from the Faculty of Chemistry at the National Autonomous University of Mexico (UNAM), her Master’s degree from the Faculty of Medicine at UNAM, and her Doctorate from the Faculty of Sciences at UNAM. She worked at the Children's Hospital of Mexico and at the National System for the Integral Development of the Family (DIF). For 34 years, she has been a full-time professor at the Universidad Autónoma Metropolitana, Xochimilco Campus since September 21, 1988.

In 2012, she was awarded membership in the National System of Researchers (SNI) by the National Council of Science and Technology (CONACyT), obtained SNI Level II in 2019, and reaffirmed SNI Level II in 2023. She received a five-year tenure scholarship from UAM on February 16, 2023 (CDA03.009.22). Her activities are based on basic research focused on the regulation of intestinal homeostasis components influenced by factors such as stress and by immunomodulatory agents like bovine lactoferrin, in collaboration with researchers from the School of Medicine (ESM) at the National Polytechnic Institute (IPN) and the Universidad Autónoma del Estado de México (UAEMEX). This research line has contributed to the training of undergraduate, graduate, and postdoctoral students under CONACyT projects.

She is the principal investigator of the research project “Effect of Bovine Lactoferrin on the Severity of Ulcerative Colitis in Stressed Mice,” in collaboration with Dr. Marycarmen Godinez-Victoria (ESM, IPN) and Dr. Fabiola Guzmán-Mejía (CONACyT Postdoctoral Fellow). She was also responsible for the research protocol “Evaluation of the Modulatory Effect of Stress and Bovine Lactoferrin on Parameters Related to Intestinal Homeostasis in BALB/c Mice,” registered on 14/05/2014, updated on 29/05/2017, and with a final report submitted on 03/07/2023. She participated in exercise and Kawasaki disease protocols led by Dr. Marycarmen Godínez Victoria and is part of the Academic Body “Study of Virulence Factors of Fungi and Bacteria and Their Role in Host-Parasite Interactions,” regulated by PROMEP during its formation (14/11/2013 and 07/11/2016) and consolidation (26/11/2019).

Her work in scientific dissemination is based on presenting posters at research conferences and publishing a popular science article in the “Avance y Perspectiva” journal in 2023. In August 2023, she participated in the organization and experimental activities for the science dissemination event “ConCiencia.” In scientific outreach, she has published articles in Mexican journals cited globally, such as “Bioactive Components of Functional Foods of Plant Origin” (Rev Mex C Farm 2006; 27(4): 58-68).

In teaching, she has participated in committees for the undergraduate modules “Fundamental Cellular Processes” and “Energy and Consumption of Fundamental Substances” of the Core Curriculum of the Division of Biological and Health Sciences (DCBS). She co-authored the laboratory manual “Basic Methods for the Isolation and Identification of Enterobacteria from Water” for the module “Fundamental Cellular Processes.” She was part of the committee for reviewing adaptations to the Core Curriculum modules (20/07/2012) and for the pedagogical design of the module “Energy and Consumption of Fundamental Substances” (29/09/2022).

In the QFB program, she participated in the committee for the extensive development of the module “Prevention and Control of Microbial Propagation” (Dec 16, 2015), in the accreditation of the QFB course before the Mexican Council for the Accreditation of Pharmaceutical Training, Civil Association (11/04/2015), and in the analysis of the productivity of the areas of the Department of Biological Systems at UAMX (19/12/2019). She participated in the Interview Committee for student admission to the Master’s in Pharmaceutical Sciences at UAMX (24/10/2019) and in the Institutional Development Committee convened by the UAMX Rectory (20/01/2020).



Information provided by the academic staff

Research interests

• Intestinal Homeostasis
• Intestinal Barrier
• Bovine Lactoferrin
• Ulverative Colitis
• Stress

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAHiguera-Martínez, G., Levaro-Loquio, D., Reséndiz-Albor, A.A. and 4 more (...) (2025).Cholinergic regulation on polymeric immunoglobulin receptor expression in Caco-2 cells. Acta Pharmaceutica,75(3) 547-555
OAGuzmán-Mejía, F., Molotla-Torres, D.E., Godínez-Victoria, M. and 4 more (...) (2024).Looking Inside of the Intestinal Permeability Regulation by Protein-Derivatives from Bovine Milk. Molecular Nutrition and Food Research,68(22)
OAHernández-Urbán, A.J., Drago-Serrano, M.-E., Reséndiz-Albor, A.A. and 4 more (...) (2024).Moderate Aerobic Exercise Induces Homeostatic IgA Generation in Senile Mice. International Journal of Molecular Sciences,25(15) | 3 |
OAHernández-Urbán, A.J., Drago-Serrano, M.E., Cruz-Baquero, A. and 5 more (...) (2023).Exercise improves intestinal IgA production by T-dependent cell pathway in adults but not in aged mice. Frontiers in Endocrinology,14
OAMolotla-Torres, D.E., Guzmán-Mejía, F., Godínez-Victoria, M. and 1 more (...) (2023).Role of Stress on Driving the Intestinal Paracellular Permeability. Current Issues in Molecular Biology,45(11) 9284-9305
OACarrizales-Luna, J.E., Reséndiz-Albor, A.A., Arciniega-Martínez, I.M. and 4 more (...) (2023).Outcomes of nicotinic modulation on markers of intestinal IgA antibody response. Biomedical Reports,18(2)
OAGuzmán-Mejía, F., Godínez-Victoria, M., García-Hernández, A.L. and 3 more (...) (2023).Regionalized analysis of gut barrier components in the small intestine of BALB/c mice following chronic immobilization stress. Advances in Clinical and Experimental Medicine,32(12)
OAGuzmán-Mejía, F., Godínez-Victoria, M., Molotla-Torres, D.E. and 1 more (...) (2023).Lactoferrin as a Component of Pharmaceutical Preparations: An Experimental Focus. Pharmaceuticals,16(2) | 3 |
OACruz-Baquero, A., Jarillo-Luna, R.A., Cárdenas-Jaramillo, L.M. and 3 more (...) (2022).Ascorbic Acid Ameriolates Liver Damage by Myeloperoxidase Oxidative Products in a Hamster Model of Amoebic Liver Abscess. Frontiers in Cellular and Infection Microbiology,12
OAMorales-Magaña, J., Arciniega-Martínez, I.M., Drago-Serrano, M.E. and 6 more (...) (2022).Cholecystokinin Outcome on Markers of Intestinal IgA Antibody Response. Current Issues in Molecular Biology,44(6) 2542-2553
Sierra-Ramírez, J.A., Saucedo-Bueno, L., García-Hernández, A.L. and 4 more (...) (2022).Moderate aerobic exercise on bone quality changes associated with aging and oxidative stress in BALB/c mice. Journal of Biomechanics,135
Arciniega-Martínez, I.M., Pacheco-Yépez, J., Santamaria-Chávez, M.M. and 6 more (...) (2022).Muscarinic receptors control markers of inflammation in the small intestine of BALB/c mice. Journal of Neuroimmunology,362
OARamírez-Rico, G., Drago-Serrano, M.E., León-Sicairos, N. and 1 more (...) (2022).Lactoferrin: A Nutraceutical with Activity against Colorectal Cancer. Frontiers in Pharmacology,13| 3 |
OAGodínez-Chaparro, B., Guzmán-Mejía, F., Drago-Serrano, M.E. (2021).Lactoferrin and Its Potential Impact for the Relief of Pain: A Preclinical Approach. Pharmaceuticals,14(9)
OAGuzmán-Mejía, F., Godínez-Victoria, M., Vega-Bautista, A. and 2 more (...) (2021).Intestinal homeostasis under stress siege. International Journal of Molecular Sciences,22(10)
Guzmán-Mejía, F., Vega-Bautista, A., Molotla-Torres, D.E. and 2 more (...) (2021).Bovine lactoferrin as a Modulator of Neuroendocrine Components of Stress. Current Molecular Pharmacology,14(6) 1037-1045| 3 |
Pérez-López, J.A., Rojas-Hernández, S., Campos-Rodríguez, R. and 4 more (...) (2020).Posterior Subdiaphragmatic Vagotomy Downmodulates the IgA Levels in the Small Intestine of BALB/c Mice. NeuroImmunoModulation,26(6) 292-300

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
Seminario VIIPosgrado
2
25O
Trabajo de Investigación IXPosgrado
3
25P
Trabajo de Investigación VIIIPosgrado
4
25I
Energía y Consumo de Substancias FundamentalesLicenciatura
5
25I
Trabajo de Investigación VIIPosgrado
6
24O
Energía y Consumo de Substancias FundamentalesLicenciatura
7
24O
Seminario VIPosgrado
8
24O
Trabajo de Investigación VIPosgrado
9
24P
Energía y Consumo de Substancias FundamentalesLicenciatura
10
24P
Seminario VPosgrado
11
24P
Trabajo de Investigación VPosgrado
12
24I
Trabajo de Investigación IVPosgrado
13
24I
Seminario IVPosgrado
14
23O
Energía y Consumo de Substancias FundamentalesLicenciatura
15
23O
Seminario IIIPosgrado
16
23O
Trabajo de Investigación IIIPosgrado
17
23P
Energía y Consumo de Substancias FundamentalesLicenciatura
18
23P
Seminario IIPosgrado
19
23P
Trabajo de Investigación IIPosgrado
20
23I
Energía y Consumo de Substancias FundamentalesLicenciatura
21
23I
Seminario IPosgrado
22
23I
Trabajo de Investigación IPosgrado
23
22O
Energía y Consumo de Substancias FundamentalesLicenciatura
24
22P
Energía y Consumo de Substancias FundamentalesLicenciatura
25
22I
Energía y Consumo de Substancias FundamentalesLicenciatura
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