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Perfil investigador
Esp
Dr. Luis Camilo Ríos Castañeda

Professor
Departament of Biological Systems

Division of Biological and Health Sciences


Emeritus
Member of the National System of Researchers
(SNII)

Medicine and Health Sciences



Xochimilco Campus

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Sustainable Development Goals

• 3 Good Health and Well-Being

• 9 Industry, Innovation, and Infrastructure


Research interests

• Development of neuroprotective drugs
• Toxicity of metals studies
• Experimental models of neurological diseases
• Development of biopolymers
• Development of cannabinoids

Profile

Doctor Luis Camilo Ríos Castañeda graduated as a Chemist, with honors, from the Faculty of Chemistry of the Universidad Nacional Autónoma de México (UNAM). In 1994, he obtained his Ph.D. in Sciences at CINVESTAV of the Instituto Politécnico Nacional (IPN), specializing in Pharmacology. At the invitation of the Newton Fund of the United Kingdom, he carried out two stays in London and Oxford through the Leaders in Innovation Fellowships program.

He has been a Professor in the QFB career and in the Master's and Doctorate Program in Pharmaceutical Sciences at the Universidad Autónoma Metropolitana (UAM) since 1989.

Dr. Ríos' research work is reflected in more than 300 articles published in international peer-reviewed scientific journals, with more than 7900 citations to his work, with an H index of 52, according to Scopus. He has been a National Researcher Level 3, of the National System of Researchers, since 2004.

He has been a tutor or co-tutor of 30 Ph.D. graduates, 35 Master of Science graduates, and about 50 undergraduate students at UNAM, UAM, CINVESTAV, IPN, UAEM, and UAZ.

He has been a member of the editorial board of the journals: Archivos de Neurociencias (1994- to date), Toxicology Letters (1996-1999), Revista Mexicana de Ciencias Farmacéuticas (2008-2015), Co-Editor of the Revista de Investigación Clínica (2009-2012) and is a Numerary Academician of the National Academy of Medicine of Mexico, Full Academician of the National Academy of Pharmaceutical Sciences and Corresponding Academician of the Royal Academy of Pharmacy of Spain.

Dr. Ríos has been the winner of several national and international research awards, such as: The Gen Award, the Glaxo-Wellcome Award, the Western Pharmacology Society Award, the National Chemistry Award, "Andrés Manuel del Río" 2011, the Award of Merit in Neurology and Neurosurgery "Dr. Manuel Velasco Suárez" 2013, presented by Mr. President of Mexico, the Hidalgo Award for Science, Technology and Innovation 2014, and one of the Awards of the Ibero-American Academy of Pharmacy in 2020.



Information provided by the academic staff

Research interests

• Development of neuroprotective drugs
• Toxicity of metals studies
• Experimental models of neurological diseases
• Development of biopolymers
• Development of cannabinoids

Academic Work

On the following pages you can consult the research work:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAHernández-Rojas, I., Aguila-Rosas, J., Castañeda Hernández, O. and 4 more (...) (2026).Copper Complexes: Emerging Micro- and Nanosystems for Dermatological Treatment. Pharmaceutics,18(7)
OARomero-Sánchez, H.A., Ríos, C., Martínez-Cárdenas, M.L.Á. and 4 more (...) (2026).Dapsone and N-Acetylcysteine Exert a Synergistic Antinociceptive Effect Associated with Oxidative Stress After Traumatic Spinal Cord Injury: An Isobolographic Study. Brain Sciences,16(8)
OAPérez-Barrón, G., Sánchez-González, K., Cruz, S.L. and 6 more (...) (2026).Antidepressant-like effect of hydroxytyrosol in a 1-methyl-4-phenylpyridinium model of Parkinson’s disease in rats. Neurochemical Research,51(2)
OAMartínez-Rodríguez, E.J., Barón-Flores, V., Ramirez-Bermudez, J. and 4 more (...) (2025).Plasma Glutathione Concentrations Are Associated with Leukocyte and Neutrophils’ Counts in Clozapine-Treated Patients. Pharmaceuticals,18(9)
OAArteaga-Silva, M., Vigueras-Villaseñor, R.M., Guillen-Herrera, G. and 6 more (...) (2025).Perinatal exposure to lead alters male reproductive behaviour and immunoreactivity of androgen and oestrogen receptors in the brain. International Journal of Experimental Pathology,106(1) 3|6
OARíos, C., Salgado-Ceballos, H., Grijalva, I. and 15 more (...) (2025).Demonstration of therapeutic effect of plasma-synthesized polypyrrole/iodine biopolymer in rhesus monkey with complete spinal cord section. Journal of Materials Science: Materials in Medicine,36(1)
Lamas-Aguilar, R., Diaz-Ruiz, A., Navarro, L. and 4 more (...) (2025).Corrigendum to: Armodafinil as a Potential Pharmacological Treatment for Attention Deficit Hyperactivity Disorder in Adults: A Review. Current Neuropharmacology,23(14)
Alvarez-Mejia, L., Cruz, G., Salgado-Ceballos, H. and 8 more (...) (2025).Polypyrrole/Iodine Biopolymers in Chronic Traumatic Spinal Cord Injuries. IFMBE Proceedings,136114-121
OAIslas-Cortez, M., Ríos, C., Manzanares, J. and 2 more (...) (2024).Isobolographic Analysis of the Cytoprotective Effect of Dapsone and Cannabidiol Alone or Combination upon Oxygen–Glucose Deprivation/Reoxygenation Model in SH-SY5Y Cells. Antioxidants,13(6)
Verduzco-Mendoza, A., Mota-Rojas, D., Olmos-Hernández, A. and 12 more (...) (2024).Changes in Noradrenergic Synthesis and Dopamine Beta-Hydroxylase Activity in Response to Oxidative Stress after Iron-induced Brain Injury. Neurochemical Research,49(11) 3043-3059
OAMata-Bermudez, A., Diaz-Ruiz, A., Silva-García, L.R. and 7 more (...) (2024).Mucuna pruriens, a Possible Treatment for Depressive Disorders. Neurology International,16(6) 1509-15273
OAMata-Bermudez, A., Trejo-Chávez, R., Martínez-Vargas, M. and 7 more (...) (2024).Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury in rats. BioMedicine (Taiwan),14(3) 23-30
OARuiz-Diaz, D., Manjarrez-Marmolejo, J., Diaz-Ruiz, A. and 7 more (...) (2024).Development and Characterization of Electrodes Coated with Plasma-Synthesized Polypyrrole Doped with Iodine, Implanted in the Rat Brain Subthalamic Nucleus. Polymers,16(6)
OAAguila-Rosas, J., García-Martínez, B.A., Ríos, C. and 6 more (...) (2024).Copper release by MOF-74(Cu): a novel pharmacological alternative to diseases with deficiency of a vital oligoelement. RSC Advances,14(2) 855-862
OAMata-Bermudez, A., Trejo-Chávez, R., Martínez-Vargas, M. and 5 more (...) (2024).Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders. Frontiers in Neuroscience,18
OAJardón-Guadarrama, G., Manríquez-Ramírez, M.E., Rodríguez-Pérez, C.E. and 5 more (...) (2024).TiO2-ZnPc nanoparticles functionalized with folic acid as a target photosensitizer for photodynamic therapy against glioblastoma cells. Journal of Materials Science: Materials in Medicine,35(1) 3
OAMayén-Lobo, Y.G., Alcaraz-Zubeldia, M., Dávila-Ortiz de Montellano, D.J. and 8 more (...) (2023).Influence of glutathione-related genetic variants on the oxidative stress profile of Mexican patients with psychotic disorders. Brazilian Journal of Psychiatry,45(2) 117-126
OAHernández-Cerón, M., Chavarria, V., Ríos, C. and 4 more (...) (2023).Melatonin in Combination with Albendazole or Albendazole Sulfoxide Produces a Synergistic Cytotoxicity against Malignant Glioma Cells through Autophagy and Apoptosis. Brain Sciences,13(6) 3
OACalderón-Estrella, F., Franco-Bourland, R.E., Rios, C. and 5 more (...) (2023).Early treatment with dapsone after spinal cord injury in rats decreases the inflammatory response and promotes long-term functional recovery. Heliyon,9(4)
OACoyoy-Salgado, A., Orozco-Barrios, C., Sánchez-Torres, S. and 12 more (...) (2023).Gene expression and locomotor recovery in adult rats with spinal cord injury and plasma-synthesized polypyrrole/iodine application combined with a mixed rehabilitation scheme. Frontiers in Neurology,14
Avila-Luna, A., Gálvez-Rosas, A., Aguirre-Pérez, A. and 5 more (...) (2023).Chronic H3R activation reduces L-Dopa-induced dyskinesia, normalizes cortical GABA and glutamate levels, and increases striatal dopamine D1R mRNA expression in 6-hydroxydopamine-lesioned male rats. Psychopharmacology,240(6) 1221-1234
Arteaga-Silva, M., Limón-Morales, O., Bonilla-Jaime, H. and 6 more (...) (2023).Effects of postnatal exposure to cadmium on male sexual incentive motivation and copulatory behavior: Estrogen and androgen receptors expression in adult brain rat. Reproductive Toxicology,120
Ríos, C., Aguirre-Aranda, I., Avendaño-Estrada, A. and 7 more (...) (2023).Characterization of the anticonvulsant effect of dapsone on metabolic activity assessed by [18F]FDG -PET after kainic acid-induced status epilepticus in rats. Brain Research,1803
Cortez-Lugo, M., Hernández-Bonilla, D., Rodríguez-Agudelo, Y. and 7 more (...) (2022).Neurocognitive function in adult residents of a mining district in Mexico after reducing manganese exposure: Follow-up after 11 years. Science of the Total Environment,848
Baron-Flores, V., Diaz-Ruiz, A., Manzanares, J. and 5 more (...) (2022).Cannabidiol attenuates hypersensitivity and oxidative stress after traumatic spinal cord injury in rats. Neuroscience Letters,788
OAMorales-Guadarrama, A., Salgado-Ceballos, H., Grijalva, I. and 12 more (...) (2022).Evolution of Spinal Cord Transection of Rhesus Monkey Implanted with Polymer Synthesized by Plasma Evaluated by Diffusion Tensor Imaging. Polymers,14(5)
OAFarías, P., Hernández-Bonilla, D., Moreno-Macías, H. and 5 more (...) (2022).Prenatal Co-Exposure to Manganese, Mercury, and Lead, and Neurodevelopment in Children during the First Year of Life. International Journal of Environmental Research and Public Health,19(20)
OADiaz-Ruiz, A., Nader-Kawachi, J., Calderón-Estrella, F. and 3 more (...) (2022).Dapsone, More than an Effective Neuro and Cytoprotective Drug. Current Neuropharmacology,20(1) 194-2103
OAVerónica, B.-F., Martínez-Rodríguez, E., Hernández-López, D. and 4 more (...) (2021).Anticonvulsant and antidepressant effect of the ethanolic extract of Annona reticulata leaves in rat. Archivos de Neurociencias,26(3) 17-233
García-Martínez, B.A., Montes, S., Tristán-López, L. and 4 more (...) (2021).Copper biodistribution after acute systemic administration of copper gluconate to rats. BioMetals,34(3) 687-700
Islas-Cortez, M., Rios, C., Rubio-Osornio, M. and 5 more (...) (2021).Characterization of the antiapoptotic effect of copper sulfate on striatal and midbrain damage induced by MPP+ in rats. NeuroToxicology,8218-25
Ortega-Vázquez, A., Mayen-Lobo, Y.G., Dávila-Ortiz de Montellano, D.J. and 5 more (...) (2021).Alcohol intake potentiates clozapine adverse effects associated to CYP1A2*1C in patients with refractory psychosis. Drug Development Research,82(5) 685-694
Mata-Bermudez, A., Ríos, C., Burelo, M. and 6 more (...) (2021).Amantadine prevented hypersensitivity and decreased oxidative stress by NMDA receptor antagonism after spinal cord injury in rats. European Journal of Pain (United Kingdom),25(8) 1839-1851
Anaya-Ramos, L., Díaz-Ruíz, A., Ríos, C. and 6 more (...) (2021).The acute systemic toxicity of thallium in rats produces oxidative stress: attenuation by metallothionein and Prussian blue. BioMetals,34(6) 1295-13113|6
Avendaño-Estrada, A., Rios, C., Aguirre-Aranda, I. and 7 more (...) (2021).Characterization of metabolic activity induced by kainic acid in adult rat whole brain at the early stage: A 18FDG-PET study. Brain Research,1769
Hernández-Rodríguez, J., López, A.L., Montes, S. and 7 more (...) (2021).Delay in puberty indices of Wistar rats caused by Cadmium. Focus on the redox system in reproductive organs. Reproductive Toxicology,9971-793
Sánchez-Torres, S., Díaz-Ruíz, A., Ríos, C. and 15 more (...) (2020).Recovery of motor function after traumatic spinal cord injury by using plasma-synthesized polypyrrole/iodine application in combination with a mixed rehabilitation scheme. Journal of Materials Science: Materials in Medicine,31(7)

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26P
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
2
26P
Trabajo de Redacción de Tesis IIPosgrado
3
26P
Seminario IIPosgrado
4
26P
Trabajo de Investigación IIPosgrado
5
26P
Proyecto de Investigación IIPosgrado
6
26I
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
7
26I
Proyecto de Investigación IPosgrado
8
26I
Seminario IPosgrado
9
26I
Trabajo de Investigación IPosgrado
10
26I
Trabajo de Redacción de Tesis IPosgrado
11
25O
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
12
25O
Seminario de Avances de Investigación VIIPosgrado
13
25O
Seminario de Investigación IIPosgrado
14
25O
Trabajo de Investigación IXPosgrado
15
25O
Trabajo de Redacción de Tesis IIIPosgrado
16
25P
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
17
25P
Proyecto de Investigación IIIPosgrado
18
25P
Seminario de Investigación IPosgrado
19
25P
Trabajo de Investigación VIII Posgrado
20
25P
Trabajo de Redacción de Tesis IIPosgrado
21
25P
Trabajo de Redacción de Tesis IIIPosgrado
22
25I
Planeación y Diseño de la Investigación en Ciencias FarmacéuticasPosgrado
23
25I
Proyecto de Investigación IIPosgrado
24
25I
Trabajo de Investigación VIIPosgrado
25
25I
Trabajo de Redacción de Tesis IPosgrado
26
25I
Trabajo de Redacción de Tesis IIPosgrado
27
25I
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
28
24O
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
29
24O
Proyecto de Investigación IPosgrado
30
24O
Seminario de Avances de Investigación VIPosgrado
31
24O
Seminario VIIPosgrado
32
24O
Trabajo de Investigación IXPosgrado
33
24O
Trabajo de Investigación VIPosgrado
34
24O
Trabajo de Redacción de Tesis IPosgrado
35
24P
Los Fármacos como Modificadores de Funciones BiológicasLicenciatura
36
24P
Proyecto de Investigación IIIPosgrado
37
24P
Seminario de Avances de Investigación VPosgrado
38
24P
Seminario de Avances de Investigación VIIPosgrado
39
24P
Trabajo de Investigación IXPosgrado
40
24P
Trabajo de Investigación VPosgrado
41
24P
Trabajo de Investigación VIIIPosgrado
42
24I
Proyecto de Investigación IIPosgrado
43
24I
Seminario de Avances de Investigación IVPosgrado
44
24I
Trabajo de Investigación IVPosgrado
45
24I
Trabajo de Investigación VIIPosgrado
46
24I
Trabajo de Investigación VIII Posgrado
47
23O
Proyecto de Investigación IPosgrado
48
23O
Proyecto de Investigación IIIPosgrado
49
23O
Seminario de Avances de Investigación IIIPosgrado
50
23O
Seminario de Avances de Investigación VIIPosgrado
51
23O
Seminario de Investigación IIPosgrado
52
23O
Seminario VIPosgrado
53
23O
Trabajo de Investigación IIIPosgrado
54
23O
Trabajo de Investigación VIPosgrado
55
23O
Trabajo de Investigación VIIPosgrado
56
23P
Proyecto de Investigación IIPosgrado
57
23P
Proyecto de Investigación IIIPosgrado
58
23P
Proyecto de Investigación IIIPosgrado
59
23P
Seminario de Avances de Investigación IIPosgrado
60
23P
Seminario de Avances de Investigación VIPosgrado
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Universidad Autónoma Metropolitana, 2026.