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Perfil investigador
Esp
Dr. Eduardo González Zamora

Professor
Departament of Chemistry

Division of Basic Sciences and Engineering


Level 3
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-Being

• 4 Quality Education

• 9 Industry, Innovation, and Infrastructure


Research interests

• Synthesis of Polyheterocycles via Multicomponent Reactions
• Click reactions
• Peptide Synthesis
• Synthesis of Polydentated binders precursors of Porous Coordination Polymers type MOF's
• Drug synthesis

Profile

Dr. Eduardo González Zamora studied his bachelor's and master's degrees in Chemistry at the UAM and his PhD in Organic Chemistry at the University of Paris XI, Orsay, France. He completed a Postdoctoral stay at the Institute of Chemistry of the UNAM and a second stay for two years at the Institute of Chemistry of Natural Substances in Gif Sur-Yvette, France.

He carried out a research stay at the Department of Chemistry and Biochemistry at the University of Los Angeles California (UCLA), USA. His main lines of research are: Total Synthesis of Natural Products, Peptide Synthesis, Synthesis of Polyheterocycles by Multicomponent Reactions, and synthesis of Polydentated binders precursors of Porous Coordination Polymers type MOF's.

He belongs to the National System of Researchers, Level III. Dr. González-Zamora has published 96 articles in indexed and refereed journals, has 7 Reviews and 13 front covers of the magazine. Dr. González-Zamora has graduated 22 bachelor's students, 7 master's students and 7 doctoral students. Dr. González-Zamora has the 2018 Research Award, awarded by the UAM, PRODEP Profile awarded by the SEP, 2019 Teaching Award awarded by the Division of Basic Sciences and Engineering of the UAM, among others.



Information provided by the academic staff

Research interests

• Synthesis of Polyheterocycles via Multicomponent Reactions
• Click reactions
• Peptide Synthesis
• Synthesis of Polydentated binders precursors of Porous Coordination Polymers type MOF's
• Drug synthesis

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OASuárez-Moreno, G., Méndez, F., Gutierrez-Carrillo, A. and 4 more (...) (2026).NMR-Based Structural Analysis of Highly Substituted Pyridines From Kondrat'eva Aza-Diels–Alder Cycloadditions. Magnetic Resonance in Chemistry,64(3) 324-332
Morales-Saavedra, O.G., Guarin, C.A., Hernández-Rojas, M.E. and 10 more (...) (2026).Synthesis and characterization of novel polymers containing poly((4-((4-nitrophenyl)ethynyl)phenyl)azanediyl)bis(ethane-2,1-diyl) as main chain and tolanic chromophores in the side chain with strong NLO-activity. Materials Chemistry and Physics,350
OALópez-Cervantes, V.B., Obeso, J.L., Flores, J.G. and 11 more (...) (2025).Formation of polysulfides as a smart strategy to selectively detect H2S in a Bi(iii)-based MOF material. Chemical Science,16(13) 5483-5492
OABlanco-Carapia, R.E., Hernández-López, R., Alcaraz-Estrada, S.L. and 9 more (...) (2025).Multi-Component Synthesis of New Fluorinated-Pyrrolo[3,4-b]pyridin-5-ones Containing the 4-Amino-7-chloroquinoline Moiety and In Vitro–In Silico Studies Against Human SARS-CoV-2. International Journal of Molecular Sciences,26(15) | 3 |
OAMarín-Rosas, P., Portillo-Veléz, N.S., Gabriel Flores, J. and 8 more (...) (2025).The Use of Porous Materials in Heterogeneous Catalysis. Journal of the Mexican Chemical Society,69(1) 259-267
OAFlores-Reyes, J.C., Amador-Sánchez, Y.A., Valderrama-Celestino, A. and 7 more (...) (2025).Dual-state emission of pyrazolyl-pyrrolo[3,4-b]pyridin-5-ones via excited-state intramolecular proton transfer (ESIPT): multicomponent synthesis and optical characterization. Organic Chemistry Frontiers,12(8) 2607-2616
OAMorales-Salazar, I., Islas-Jácome, P., Herrera-Zuñiga, L.D. and 5 more (...) (2025).Multicomponent Synthesis of Fluorine-Containing Bioactive Compounds and Drugs. European Journal of Organic Chemistry,28(38)
OAMorales-Salazar, I., Bouillon, J.-P., González-Zamora, E. and 1 more (...) (2025).Non-Isocyanide-Based Three-Component Reactions: From Strecker to Nowadays. Journal of the Mexican Chemical Society,69(1) 185-258
OABlanco-Carapia, R.E., Islas-Jácome, A., González-Zamora, E. (2025).7,7′-(1,4-Phenylene)bis(2-benzyl-3-(3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one). MolBank,2025(4)
OALópez-Cervantes, V.B., Martínez, M.L., Obeso, J.L. and 9 more (...) (2024).UTSA-16(Zn) for SO2 detection: elucidating the fluorescence mechanism. Dalton Transactions,54(4) 1646-1654
OAMorales-Salazar, I., Garduño-Albino, C.E., Montes-Enríquez, F.P. and 8 more (...) (2024).In Vitro and In Silico Studies of Bis-furyl-pyrrolo[3,4-b]pyridin-5-ones on Dengue Virus. Journal of the Mexican Chemical Society,68(1) 170-183| 3 |
Flores-Reyes, J.C., Rojas-Montoya, S.M., Blancarte-Carrazco, L. and 6 more (...) (2024).Multicomponent synthesis and photophysical properties of meso-thienyl BODIPY-pyrrolo[3,4-b]pyridin-5-ones. An experimental and theoretical study. Journal of Luminescence,273
OAFlores-Reyes, J.C., Galano, A., Rojas-Montoya, S.M. and 6 more (...) (2024).Synthesis of BODIPY-pyrrolo[3,4-b]pyridin-5-ones via Ugi-Zhu/cascade reactions and studies of fluorescence response toward viscosity. Frontiers in Chemistry,12
Flores-Reyes, J.C., Valderrama-Celestino, A., Trejo-Velasco, M.F. and 6 more (...) (2024).Multicomponent synthesis of 7-(diethylamino)coumarin–pyrrolo[3,4-b]pyridin-5-one conjugates and modulation of their twisted intramolecular charge transfer (TICT) processes. Tetrahedron,168
Blanco-Carapia, R.E., Islas-Jácome, P., Gutiérrez-Carrillo, A. and 3 more (...) (2024).One-pot synthesis of phenyl- and biphenyl-linked bis-pyrrolo[3,4-b]pyridin-5-ones via a pseudo-repetitive Ugi-Zhu-5CR coupled to a double cascade process (aza-Diels-Alder/N-acylation/decarboxylation/dehydration). Tetrahedron Letters,151
OABlanco-Carapia, R.E., Aguilar-Rangel, E.A., Rincón-Guevara, M.A. and 2 more (...) (2023).Synthesis of New Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy. Molecules,28(10)
OAFlores-Reyes, J.C., Cotlame-Salinas, V.D.C., Ibarra, I.A. and 2 more (...) (2023).Pseudo-multicomponent reactions. RSC Advances,13(24) 16091-16125
OAIslas-Jácome, P., García-Falcón, C., Castañón-Alonso, S.L. and 4 more (...) (2023).2-Benzyl-7-(4-chlorophenyl)-3-morpholino-6-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one. MolBank,2023(3)
OAMorales-Salazar, I., Garduño-Albino, C.E., Montes-Enríquez, F.P. and 5 more (...) (2023).Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma. Pharmaceuticals,16(11) | 3 |
López-Cervantes, V.B., Obeso, J.L., Yañez-Aulestia, A. and 5 more (...) (2023).MFM-300(Sc): a chemically stable Sc(iii)-based MOF material for multiple applications. Chemical Communications,59(69) 10343-10359
OAFlores, J.G., Obeso, J.L., Martínez-Jiménez, V. and 11 more (...) (2023).Evaluation of the catalytic activity of Zn-MOF-74 for the alcoholysis of cyclohexene oxide. RSC Advances,13(39) 27174-27179
López-Olvera, A., Zárate, J.A., Obeso, J.L. and 5 more (...) (2023).SO2 Capture at Low Pressure in a Prototypical MIL-53 Aluminum MOF Family: The Influence of Pore Expansion. Inorganic Chemistry,62(51) 20901-20905
Obeso, J.L., López-Olvera, A., Flores, C.V. and 11 more (...) (2022).Methylene blue adsorption in DUT-5: Relatively strong host-guest interactions elucidated by FTIR, solid-state NMR, and XPS. Journal of Molecular Liquids,368
OAMorales-Salazar, I., Montes-Enríquez, F.P., Garduño-Albino, C.E. and 9 more (...) (2022).Synthesis of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones via Ugi-Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins. RSC Medicinal Chemistry,14(1) 154-165| 3 |
Gupta, N.K., López-Olvera, A., González-Zamora, E. and 2 more (...) (2022).Sulfur Dioxide Capture in Metal-Organic Frameworks, Metal-Organic Cages, and Porous Organic Cages. ChemPlusChem,87(6)
Zárate, J.A., González-Zamora, E., Ibarra, I.A. and 1 more (...) (2022).SO2 capture enhancement due to confined methanol within MIL-53(Al)-TDC. Dalton Transactions,52(1) 16-19
OABlanco-Carapia, R.E., Aguilar-Rangel, E.A., Islas-Jácome, A. and 1 more (...) (2022).Ferrocenyl-bis-(1-(4-benzyl-5-morpholinooxazol-2-yl)-N-(4-(trifluoromethyl)benzyl)methanamine). MolBank,2022(3)
OAMorales-Salazar, I., Rincón-Guevara, M.A., González-Zamora, E. and 1 more (...) (2022).2-Benzyl-3-morpholino-7-(thiophen-2-yl)-6-(thiophen-2-ylmethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one. MolBank,2022(4)
López-Olvera, A., Montes-Andrés, H., Martínez-Ahumada, E. and 8 more (...) (2021).Understanding the Mechanism of Amorphization for Co-URJC-5. European Journal of Inorganic Chemistry,2021(43) 4458-4462
Flores-Reyes, J.C., Islas-Jácome, A., González-Zamora, E. (2021).The Ugi three-component reaction and its variants. Organic Chemistry Frontiers,8(19) 5460-5515
OACotlame-Salinas, V.D.C., López-Olvera, A., Islas-Jácome, A. and 2 more (...) (2021).CO2capture enhancement in MOFs: Via the confinement of molecules. Reaction Chemistry and Engineering,6(3) 441-453| 13 |
Flores, J.G., Zárate-Colín, J.A., Sánchez-González, E. and 12 more (...) (2020).Partially Reversible H2S Adsorption by MFM-300(Sc): Formation of Polysulfides. ACS Applied Materials and Interfaces,12(16) 18885-18892| 7 |
Díaz-Ramírez, M.L., Vargas, B., Raziel Álvarez, J. and 11 more (...) (2020).Fluorometric detection of iodine by MIL-53(Al)-TDC. Dalton Transactions,49(20) 6572-6577
Alvarado-Alvarado, D., González-Estefan, J.H., Flores, J.G. and 9 more (...) (2020).Water Adsorption Properties of Fe(pz)[Pt(CN)4] and the Capture of CO2 and CO. Organometallics,39(7) 949-955| 13 |
Barrios-Vargas, L.J., Ruiz-Montoya, J.G., Landeros-Rivera, B. and 8 more (...) (2020).Confined benzene within InOF-1: Contrasting CO2 and SO2 capture behaviours. Dalton Transactions,49(9) 2786-2793| 13 |
OASánchez-González, E., Flores, J.G., Flores-Reyes, J.C. and 7 more (...) (2020).Bottleneck effect explained by Le Bail Refinements: Structure transformation of Mg-CUK-1 by confining H2O molecules. Materials,13(8) | 13 |
Martínez-Ahumada, E., López-Olvera, A., Jancik, V. and 5 more (...) (2020).MOF Materials for the Capture of Highly Toxic H2S and SO2. Organometallics,39(7) 883-915
OAÁguila-Rosas, J., Quirino-Barreda, T., Leyva-Gómez, G. and 3 more (...) (2020).Sulfadiazine hosted in MIL-53(Al) as a biocide topical delivery system. RSC Advances,10(43) 25645-25651

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26I
Laboratorio de FarmoquímicaLicenciatura
2
26I
Química Orgánica IIILicenciatura
3
26I
Introducción a la Investigación IIPosgrado
4
25O
Introducción a la Investigación IPosgrado
5
25O
Introducción a la Investigación IPosgrado
6
25O
Proyecto Terminal II Química OrgánicaLicenciatura
7
25O
Química Orgánica IIILicenciatura
8
25O
Resonancia Magnética NuclearLicenciatura
9
25O
Trabajo de Investigación IIIPosgrado
10
25P
Laboratorio de FarmoquímicaLicenciatura
11
25P
Trabajo de Investigación IIPosgrado
12
25P
Química Orgánica IILicenciatura
13
25P
Proyecto Terminal II Química OrgánicaLicenciatura
14
25P
Proyecto Terminal II Química OrgánicaLicenciatura
15
25P
Proyecto Terminal I Química OrgánicaLicenciatura
16
25P
Introducción a la Investigación IIIPosgrado
17
25I
Proyecto Terminal I Química OrgánicaLicenciatura
18
25I
Trabajo de Investigación IPosgrado
19
25I
Resonancia Magnética NuclearLicenciatura
20
25I
Química Orgánica IILicenciatura
21
25I
Química de Radicales LibresPosgrado
22
25I
Proyecto Terminal I Química OrgánicaLicenciatura
23
25I
Introducción a la Investigación IIIPosgrado
24
25I
Introducción a la Investigación IIPosgrado
25
24O
Introducción a la Investigación IPosgrado
26
24O
Introducción a la Investigación IIPosgrado
27
24O
Introducción a la Investigación IIIPosgrado
28
24O
Laboratorio de FarmoquímicaLicenciatura
29
24O
Química Orgánica ILicenciatura
30
24P
Introducción a la Investigación IPosgrado
31
24P
Introducción a la Investigación IIPosgrado
32
24P
Proyecto Terminal II Química OrgánicaLicenciatura
33
24P
Química Orgánica IIILicenciatura
34
24P
Síntesis TotalPosgrado
35
24I
Química de Radicales LibresPosgrado
36
24I
Química Orgánica IILicenciatura
37
24I
Trabajo de Investigación VIPosgrado
38
24I
Laboratorio de FarmoquímicaLicenciatura
39
24I
Proyecto Terminal I Química OrgánicaLicenciatura
40
24I
Introducción a la Investigación IPosgrado
41
24I
Proyecto Terminal II Química OrgánicaLicenciatura
42
23O
Laboratorio de FarmoquímicaLicenciatura
43
23O
Proyecto Terminal I Química OrgánicaLicenciatura
44
23O
Química Orgánica ILicenciatura
45
23O
Síntesis TotalPosgrado
46
23P
Química de Radicales LibresPosgrado
47
23P
Química Orgánica IIILicenciatura
48
23P
Proyecto Terminal II Química OrgánicaLicenciatura
49
23P
Laboratorio de FarmoquímicaLicenciatura
50
23I
Proyecto Terminal I Química OrgánicaLicenciatura
51
23I
Proyecto Terminal II Química OrgánicaLicenciatura
52
23I
Proyecto Terminal II Química OrgánicaLicenciatura
53
23I
Química Orgánica IILicenciatura
54
22O
Proyecto Terminal I Química OrgánicaLicenciatura
55
22O
Trabajo de Investigación VIPosgrado
56
22O
Trabajo de Investigación VPosgrado
57
22O
Resonancia MagnéticaPosgrado
58
22O
Química Orgánica IIILicenciatura
59
22O
Proyecto Terminal I Química OrgánicaLicenciatura
60
22O
Laboratorio de FarmoquímicaLicenciatura
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Universidad Autónoma Metropolitana, 2026.