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Perfil investigador
Esp
Dr. Rafael Arturo Zubillaga Luna

Professor
Departament of Chemistry

Division of Basic Sciences and Engineering


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Host-guest interaction thermodynamics
• Drug discovery for diseases of national interest

Profile

Professor Zubillaga obtained his Bachelor's Degree in Chemistry in 1984 and his Master's Degree in Chemistry in 1987 at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus. In 1994 he obtained a Doctor of Science degree from the same university, conducting his research at the Universidad Nacional Autónoma de México (UNAM) Institute of Cellular Physiology with Dr. Armando Gómez Puyou.

He has been a Professor in the Department of Chemistry at UAM Iztapalapa Campus since 1996. He has carried out research stays at the Institute of Biotechnology and Biomedicine (UAB) in Barcelona, Spain (2011), at the Institute of Agrochemistry and Food Technology in Valencia, Spain ( 2000), at the Texas College of Osteopathic Medicine in Forth Worth (1992) and at the Venezuelan Institute for Scientific Research (1991).

He has directed five doctoral theses and six master's theses. He has published 28 research articles in indexed journals. He obtained the Research Prize 2011 awarded by the UAM. He is a founding member of the Protein Physical Chemistry, Structure and Design Branch of the Mexican Biochemical Society (2006).

He is a referee of the Journal of Molecular Catalysis B: Enzymatic, Biochimica et Biophysica Acta, and Thermochimica Acta of Elsevier Publishing, as well as Springer's World Journal of Microbiology and Biotechnology. He is also an academic evaluator of CONACYT projects.



Information provided by the academic staff

Research interests

• Host-guest interaction thermodynamics
• Drug discovery for diseases of national interest

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAMiranda-Blancas, R., García-Gutiérrez, P., Sánchez-Juárez, C. and 7 more (...) (2025).Structural insights into sigma class glutathione transferase from Taenia solium: Analysis and functional implications. PLOS Neglected Tropical Diseases,19(5) | 3 |
OASánchez Juárez, C., Sánchez Pérez, L.C., Zubillaga, R.A. and 7 more (...) (2025).Effect of Glutathione on the Stability, Dynamics and Catalysis of Two Different Classes of Glutathione Transferases from Taenia solium. Journal of the Mexican Chemical Society,69(1) 39-47
OASánchez-Juárez, C., Flores-López, R., Sánchez-Pérez, L.D.C. and 4 more (...) (2025).Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from Taenia solium Using Computational and Bioinformatics Tools. Biomolecules,15(1)
OAGarduño-Juárez, R., Tovar-Anaya, D.O., Perez-Aguilar, J.M. and 4 more (...) (2024).Molecular Dynamic Simulations for Biopolymers with Biomedical Applications. Polymers,16(13) | 9 |
OAMiranda-Blancas, R., Rodríguez-Lima, O., García-Gutiérrez, P. and 5 more (...) (2024).Biochemical characterization and gene structure analysis of the 24-kDa glutathione transferase sigma from Taenia solium. FEBS Open Bio,14(5) 726-739
OASánchez Pérez, L.D.C., Zubillaga, R.A., García-Gutiérrez, P. and 1 more (...) (2024).Sigma-Class Glutathione Transferases (GSTσ): A New Target with Potential for Helminth Control. Tropical Medicine and Infectious Disease,9(4)
García-Gutiérrez, P., Camarillo-Cadena, M., Vera-Robles, L.I. and 2 more (...) (2022).Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy,274
OAGarcía-Gutiérrez, P., Zubillaga, R.A., Ibarra, I.A. and 3 more (...) (2021).Non-conventional interactions of N3 inhibitor with the main protease of SARS-CoV and SARS-CoV-2. Computational and Structural Biotechnology Journal,194669-4675| 3 |
Martínez, A., García-Gutiérrez, P., Zubillaga, R.A. and 2 more (...) (2021).Main interactions of dopamine and risperidone with the dopamine D2 receptor. Physical Chemistry Chemical Physics,23(26) 14224-14230
García-Gutiérrez, P., Zubillaga, R.A., Téllez-Plancarte, A. and 3 more (...) (2020).Discovery of a new non-substrate inhibitor of the 26.5 kDa glutathione transferase from Taenia solium by virtual screening. Journal of Molecular Graphics and Modelling,100

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
25O
Temas Selectos en FarmoquímicaLicenciatura
2
25O
Estructura de la MateriaLicenciatura
3
25O
Seminario VIIPosgrado
4
25O
Trabajo de Investigación IXPosgrado
5
25P
BiofisicoquímicaPosgrado
6
25P
Introducción a la Investigación IIIPosgrado
7
25P
Introducción a la Investigación IIIPosgrado
8
25P
Trabajo de Investigación VIIIPosgrado
9
25I
Bioquímica y Biología Molecular ILicenciatura
10
25I
Temas Selectos de BiofisicoquímicaPosgrado
11
25I
Introducción a la Investigación IIPosgrado
12
25I
Trabajo de Investigación VIIPosgrado
13
24O
Transformaciones QuímicasLicenciatura
14
24O
Bioquímica y Biología Molecular ILicenciatura
15
24O
Introducción a la Investigación IPosgrado
16
24O
Trabajo de Investigación VIPosgrado
17
24O
Seminario VIPosgrado
18
24O
Trabajo de Investigación VIPosgrado
19
24P
Trabajo de Investigación VPosgrado
20
24P
BiofisicoquímicaPosgrado
21
24P
Introducción a la Investigación IIIPosgrado
22
24I
Bioquímica y Biología Molecular ILicenciatura
23
24I
Introducción a la Investigación IIPosgrado
24
24I
Introducción a la Investigación IIIPosgrado
25
24I
Trabajo de Investigación IVPosgrado
26
23O
Estructura de la MateriaLicenciatura
27
23O
Temas Selectos de BiofisicoquímicaPosgrado
28
23O
Introducción a la Investigación IPosgrado
29
23O
Introducción a la Investigación IIPosgrado
30
23P
Introducción a la Investigación IPosgrado
31
23P
Trabajo de Investigación IIIPosgrado
32
23P
BiofisicoquímicaPosgrado
33
23I
Técnicas Experimentales en BiofisicoquímicaPosgrado
34
23I
Trabajo de Investigación IIPosgrado
35
22O
Estructura de la MateriaLicenciatura
36
22O
Introducción a la Investigación IPosgrado
37
22O
Trabajo de Investigación IPosgrado
38
22P
Introducción a la Investigación IIIPosgrado
39
22I
Diseño de FármacosLicenciatura
40
22I
Introducción a la Investigación IIPosgrado
41
22I
Introducción a la Investigación IIIPosgrado
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