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Perfil investigador
Esp
Dr. Rafael Arturo Zubillaga Luna

Professor
Departament of Chemistry

Division of Basic Sciences and Engineering


Level 2
Member of the National System of Researchers
(SNII)

Biology and chemistry



Iztapalapa Campus

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Sustainable Development Goals

• 3 Good Health and Well-being


Research interests

• Host-guest interaction thermodynamics
• Drug discovery for diseases of national interest

Profile

Professor Zubillaga obtained his Bachelor's Degree in Chemistry in 1984 and his Master's Degree in Chemistry in 1987 at the Universidad Autónoma Metropolitana (UAM) Iztapalapa Campus. In 1994 he obtained a Doctor of Science degree from the same university, conducting his research at the Universidad Nacional Autónoma de México (UNAM) Institute of Cellular Physiology with Dr. Armando Gómez Puyou.

He has been a Professor in the Department of Chemistry at UAM Iztapalapa Campus since 1996. He has carried out research stays at the Institute of Biotechnology and Biomedicine (UAB) in Barcelona, Spain (2011), at the Institute of Agrochemistry and Food Technology in Valencia, Spain ( 2000), at the Texas College of Osteopathic Medicine in Forth Worth (1992) and at the Venezuelan Institute for Scientific Research (1991).

He has directed five doctoral theses and six master's theses. He has published 28 research articles in indexed journals. He obtained the Research Prize 2011 awarded by the UAM. He is a founding member of the Protein Physical Chemistry, Structure and Design Branch of the Mexican Biochemical Society (2006).

He is a referee of the Journal of Molecular Catalysis B: Enzymatic, Biochimica et Biophysica Acta, and Thermochimica Acta of Elsevier Publishing, as well as Springer's World Journal of Microbiology and Biotechnology. He is also an academic evaluator of CONACYT projects.



Information provided by the academic staff

Research interests

• Host-guest interaction thermodynamics
• Drug discovery for diseases of national interest

Academic Work

On the following pages you can consult the research work:



Other sites of interest

Consult the research work on other websites:






Some examples of publications

Select the bibliographic reference to consult each publication:


Open Access References UN SDGs
OAGutiérrez-Flores, J., Padilla-Bernal, G., Sánchez-Juárez, C. and 5 more (...) (2026).Residue-Level Affinity Decomposition via Quantum Electron Density: A Multivariable Framework Applied to HIV-1 Protease Inhibitors. Journal of Physical Chemistry B,130(15) 4080-4093| 3 |
OASánchez Juárez, C., Sánchez Pérez, L.C., Zubillaga, R.A. and 7 more (...) (2025).Effect of Glutathione on the Stability, Dynamics and Catalysis of Two Different Classes of Glutathione Transferases from Taenia solium. Journal of the Mexican Chemical Society,69(1) 39-47
OAMiranda-Blancas, R., García-Gutiérrez, P., Sánchez-Juárez, C. and 7 more (...) (2025).Structural insights into sigma class glutathione transferase from Taenia solium: Analysis and functional implications. PLOS Neglected Tropical Diseases,19(5) | 3 |
OASánchez-Juárez, C., Flores-López, R., Sánchez-Pérez, L.D.C. and 4 more (...) (2025).Discovery and Characterization of Two Selective Inhibitors for a Mu-Class Glutathione S-Transferase of 25 kDa from Taenia solium Using Computational and Bioinformatics Tools. Biomolecules,15(1)
OAMiranda-Blancas, R., Rodríguez-Lima, O., García-Gutiérrez, P. and 5 more (...) (2024).Biochemical characterization and gene structure analysis of the 24-kDa glutathione transferase sigma from Taenia solium. FEBS Open Bio,14(5) 726-739
OAGarduño-Juárez, R., Tovar-Anaya, D.O., Perez-Aguilar, J.M. and 4 more (...) (2024).Molecular Dynamic Simulations for Biopolymers with Biomedical Applications. Polymers,16(13) | 9 |
OASánchez Pérez, L.D.C., Zubillaga, R.A., García-Gutiérrez, P. and 1 more (...) (2024).Sigma-Class Glutathione Transferases (GSTσ): A New Target with Potential for Helminth Control. Tropical Medicine and Infectious Disease,9(4)
García-Gutiérrez, P., Camarillo-Cadena, M., Vera-Robles, L.I. and 2 more (...) (2022).Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy,274
OAGarcía-Gutiérrez, P., Zubillaga, R.A., Ibarra, I.A. and 3 more (...) (2021).Non-conventional interactions of N3 inhibitor with the main protease of SARS-CoV and SARS-CoV-2. Computational and Structural Biotechnology Journal,194669-4675| 3 |
Martínez, A., García-Gutiérrez, P., Zubillaga, R.A. and 2 more (...) (2021).Main interactions of dopamine and risperidone with the dopamine D2 receptor. Physical Chemistry Chemical Physics,23(26) 14224-14230
García-Gutiérrez, P., Zubillaga, R.A., Téllez-Plancarte, A. and 3 more (...) (2020).Discovery of a new non-substrate inhibitor of the 26.5 kDa glutathione transferase from Taenia solium by virtual screening. Journal of Molecular Graphics and Modelling,100

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Courses taught by the professor in recent trimesters

*Courses are conducted in spanish

Num.Trim.Course NameLevel
1
26I
Estructura de la MateriaLicenciatura
2
26I
Proyecto Terminal I BiofisicoquímicaLicenciatura
3
26I
Trabajo de Investigación IPosgrado
4
26I
Bioquímica y Biología Molecular ILicenciatura
5
25O
Estructura de la MateriaLicenciatura
6
25O
Seminario VIIPosgrado
7
25O
Temas Selectos en FarmoquímicaLicenciatura
8
25O
Trabajo de Investigación IXPosgrado
9
25P
BiofisicoquímicaPosgrado
10
25P
Introducción a la Investigación IIIPosgrado
11
25P
Introducción a la Investigación IIIPosgrado
12
25P
Trabajo de Investigación VIIIPosgrado
13
25I
Bioquímica y Biología Molecular ILicenciatura
14
25I
Trabajo de Investigación VIIPosgrado
15
25I
Temas Selectos de BiofisicoquímicaPosgrado
16
25I
Introducción a la Investigación IIPosgrado
17
24O
Bioquímica y Biología Molecular ILicenciatura
18
24O
Introducción a la Investigación IPosgrado
19
24O
Seminario VIPosgrado
20
24O
Trabajo de Investigación VIPosgrado
21
24O
Trabajo de Investigación VIPosgrado
22
24O
Transformaciones QuímicasLicenciatura
23
24P
BiofisicoquímicaPosgrado
24
24P
Trabajo de Investigación VPosgrado
25
24P
Introducción a la Investigación IIIPosgrado
26
24I
Bioquímica y Biología Molecular ILicenciatura
27
24I
Introducción a la Investigación IIPosgrado
28
24I
Introducción a la Investigación IIIPosgrado
29
24I
Trabajo de Investigación IVPosgrado
30
23O
Estructura de la MateriaLicenciatura
31
23O
Introducción a la Investigación IPosgrado
32
23O
Introducción a la Investigación IIPosgrado
33
23O
Temas Selectos de BiofisicoquímicaPosgrado
34
23P
Introducción a la Investigación IPosgrado
35
23P
Trabajo de Investigación IIIPosgrado
36
23P
BiofisicoquímicaPosgrado
37
23I
Técnicas Experimentales en BiofisicoquímicaPosgrado
38
23I
Trabajo de Investigación IIPosgrado
39
22O
Estructura de la MateriaLicenciatura
40
22O
Introducción a la Investigación IPosgrado
41
22O
Trabajo de Investigación IPosgrado
42
22P
Introducción a la Investigación IIIPosgrado
43
22I
Diseño de FármacosLicenciatura
44
22I
Introducción a la Investigación IIPosgrado
45
22I
Introducción a la Investigación IIIPosgrado
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