Academic Work

• ORCID
• ResearchGate
• Scopus

Sites of interest

• Personal Web Site

Academic Group

• Mammalian fertilization

Sustainable Development Goals

Research interests

• In vitro Fertilization in Mammals
• Reproductive Toxicology
• Asisted Experimental Reproduction

Profile

Professor José Miguel Betancourt Rule is a Biologist (1969) with a Master's degree (1971) and Ph.D. (1974) in Biology from the Faculty of Sciences of the Universidad Nacional Autónoma de México (UNAM).He joined the Universidad Autónoma Metropolitana (UAM) in 1974 as a full-time professor in the Department of Health Sciences, where he has worked uninterruptedly.

At UAM, he has held various positions, such as Coordinator of the teaching laboratories, Head of the Research Area in Cellular and Molecular Biology, and Head of the Department of Health Sciences in the division of CBS. He was also the first Coordinator of the Doctorate in Biological Health Sciences. Professor Betancourt has published more than 100 articles in international journals and more than 19 in national journals, with 1726 citations to articles registered in Research Gate and more than 14 chapters in specialized books and textbooks.

He has trained several students, now professors at UAM, who currently have their independent research groups in various fields of knowledge such as: "Malnutrition and analysis with flow cytometry," "Molecular biology and toxicology of gametogenesis," "Andrology," "Gene expression-proteomics" and Professor Betancourt's "Cell biology and fertilization in mammals."

He has received awards such as "Distinguished Professor" from the Academic College of the UAM in 1998. "Merit in Genetics" was awarded by the Mexican Society of Genetics in 1999. "Distinguished Academician" awarded by the Academy of Research in Reproductive Biology in 2011. He is a Mexican Society of Genetics member and the "Academia de Investigación en Biología de la Reproducción AC".

Throughout 50 years of doing scientific research in the field of biology in topics associated with health, the research group to which he belongs contributed initially to the knowledge of the effects of malnutrition at the cellular level, later in the field of assisted reproduction obtaining pigs and sheep by in vitro fertilization, and the impact of gamete cryopreservation. On the other hand, in the field of reproductive toxicology, they have provided information about the damage caused to health by various chemical agents to which we are exposed daily, such as insecticides, herbicides, perfluorinated products, and parabens. The research model used to date is mainly porcine oocytes and spermatozoa (in vitro studies).

Information provided by the academic staff

Research interests

• In vitro Fertilization in Mammals
• Reproductive Toxicology
• Asisted Experimental Reproduction

Academic Work

On the following pages you can consult the research work:

• ResearchGate

See publications

• Scopus

See publications

• ORCID

See publications

Other sites of interest

Consult the research work on other websites:

• Personal website

See information

Academic Group

Consult the information provided by the Academic Group

• Mammalian fertilization

See information

Some examples of publications

Select the bibliographic reference to consult each publication:

Open Access	References	UN SDGs
	Casillas, F., Flores-González, A., Juárez-Rojas, L. and 6 more (...) (2023).Chronic stress decreases fertility parameters in female rats. Systems Biology in Reproductive Medicine,69(3) 234-244
OA	Juárez-Rojas, L., Casillas, F., López, A. and 3 more (...) (2022).Physiological role of reactive oxygen species in testis and epididymal spermatozoa. Andrologia,54(4)
	Solano, F., Hernández, E., Juárez-Rojas, L. and 9 more (...) (2022).Reproductive disruption in adult female and male rats prenatally exposed to mesquite pod extract or daidzein. Reproductive Biology,22(3)
OA	Casillas, F., Betancourt, M., Juárez-Rojas, L. and 6 more (...) (2021).Chronic stress detrimentally affects in vivo maturation in rat oocytes and oocyte viability at all phases of the estrous cycle. Animals,11(9)
OA	López, A., Ducolomb, Y., Casas, E. and 3 more (...) (2021).Effects of Porcine Immature Oocyte Vitrification on Actin Microfilament Distribution and Chromatin Integrity During Early Embryo Development in vitro. Frontiers in Cell and Developmental Biology,9
OA	López, A., Betancourt, M., Ducolomb, Y. and 7 more (...) (2021).DNA damage in cumulus cells generated after the vitrification of in vitro matured porcine oocytes and its impact on fertilization and embryo development. Porcine Health Management,7(1)
	Martínez-Quezada, R., González-Castañeda, G., Bahena, I. and 10 more (...) (2021).Effect of perfluorohexane sulfonate on pig oocyte maturation, gap-junctional intercellular communication, mitochondrial membrane potential and DNA damage in cumulus cells in vitro. Toxicology in Vitro,70
	Barajas-Salinas, A., Ducolomb, Y., Betancourt, M. and 9 more (...) (2021).Effects of methylparaben on in vitro maturation of porcine oocytes. Journal of Applied Toxicology,41(2) 330-337
OA	López, A., Betancourt, M., Casas, E. and 3 more (...) (2021).The need for regulation in the practice of human assisted reproduction in Mexico. An overview of the regulations in the rest of the world. Reproductive Health,18(1)	\| 16 \|
OA	Casillas, F., Ducolomb, Y., López, A. and 1 more (...) (2020).Effect of porcine immature oocyte vitrification on oocyte-cumulus cell gap junctional intercellular communication. Porcine Health Management,6(1)
	Retana-Márquez, S., Juárez-Rojas, L., Ávila-Quintero, A. and 5 more (...) (2020).Neuroendocrine disruption is associated to infertility in chronically stressed female rats. Reproductive Biology,20(4) 474-483
	Domínguez, A., Salazar, Z., Betancourt, M. and 11 more (...) (2019).Effect of perfluorodecanoic acid on pig oocyte viability, intracellular calcium levels and gap junction intercellular communication during oocyte maturation in vitro. Toxicology in Vitro,58224-229
OA	López-Arellano, P., López-Arellano, K., Luna, J. and 12 more (...) (2019).Perfluorooctanoic acid disrupts gap junction intercellular communication and induces reactive oxygen species formation and apoptosis in mouse ovaries. Environmental Toxicology,34(1) 92-98
	Chaparro-Ortega, A., Betancourt, M., Rosas, P. and 5 more (...) (2018).Endocrine disruptor effect of perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) on porcine ovarian cell steroidogenesis. Toxicology in Vitro,4686-93	\| 3 \|
OA	Casillas, F., Betancourt, M., Cuello, C. and 4 more (...) (2018).An efficiency comparison of different in vitro fertilization methods: IVF, ICSI, and PICSI for embryo development to the blastocyst stage from vitrified porcine immature oocytes. Porcine Health Management,4(1)
	Flores, D., Souza, V., Betancourt, M. and 7 more (...) (2017).Oxidative stress as a damage mechanism in porcine cumulus-oocyte complexes exposed to malathion during in vitro maturation. Environmental Toxicology,32(6) 1669-1678
OA	Hernández-Pichardo, J.E., Ducolomb, Y., Romo, S. and 4 more (...) (2016).Pronuclear formation by ICSI using chemically activated ovine oocytes and zona pellucida bound sperm. Journal of Animal Science and Biotechnology,7(1)
	Domínguez, A., Salazar, Z., Arenas, E. and 6 more (...) (2016).Effect of perfluorooctane sulfonate on viability, maturation and gap junctional intercellular communication of porcine oocytes in vitro. Toxicology in Vitro,3593-99
	Casillas, F., Ducolomb, Y., Lemus, A.E. and 2 more (...) (2015).Porcine embryo production following in vitro fertilization and intracytoplasmic sperm injection from vitrified immature oocytes matured with a granulosa cell co-culture system. Cryobiology,71(2) 299-305
	Moreno, D.L., Salazar, Z., Betancourt, M. and 4 more (...) (2014).Sebox plays an important role during the early mouse oogenesis in vitro. Zygote,22(1) 64-68
OA	Saavedra, M.D., Mondéjar, I., Coy, P. and 5 more (...) (2014).Calreticulin from suboolemmal vesicles affects membrane regulation of polyspermy. Reproduction,147(3) 369-378
	Casillas, F., Teteltitla-Silvestre, M., Ducolomb, Y. and 4 more (...) (2014).Co-culture with granulosa cells improve the in vitro maturation ability of porcine immature oocytes vitrified with cryolock. Cryobiology,69(2) 299-304
	Bahena, I., Xu, E., Betancourt, M. and 4 more (...) (2014).Role of Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells in mice in vitro. Zygote,22(4) 513-520
	Ducolomb, Y., González-Márquez, H., Fierro, R. and 6 more (...) (2013).Effect of porcine follicular fluid proteins and peptides on oocyte maturation and their subsequent effect on in vitro fertilization. Theriogenology,79(6) 896-904

Courses offered

*Courses are conducted in spanish

Num.	Trim.	Course Name	Level
1	23O	Introducción a la Investigación II	Licenciatura
2	23O	Proyecto de Investigación II	Licenciatura
3	23O	Proyecto de Investigación I	Licenciatura
4	23P	Introducción a la Investigación II	Licenciatura
5	23P	Proyecto de Investigación I	Licenciatura
6	23I	Seminario III	Posgrado
7	23I	Trabajo Experimental III	Posgrado
8	23I	Análisis de Resultados y Escritura de Tesis	Posgrado
9	22O	Introducción a la Investigación II	Licenciatura
10	22O	Trabajo de Investigación VII	Posgrado
11	22O	Seminario I	Posgrado
12	22O	Trabajo Experimental I	Posgrado
13	22O	Seminario II	Posgrado
14	22O	Trabajo Experimental II	Posgrado
15	22P	Introducción a la Investigación II	Licenciatura
16	22P	Trabajo de Investigación VI	Posgrado
17	22P	Seminario I	Posgrado
18	22P	Trabajo Experimental I	Posgrado
19	22P	Temas Selectos de Biología de la Reproducción I	Posgrado
20	22P	Seminario III	Posgrado
21	22P	Trabajo Experimental III	Posgrado
22	22P	Análisis de Resultados y Escritura de Tesis	Posgrado
23	22I	Trabajo de Investigación V	Posgrado
24	22I	Seminario II	Posgrado
25	22I	Trabajo Experimental II	Posgrado
26	21O	Introducción a la Investigación II	Licenciatura
27	21O	Seminario I	Posgrado
28	21O	Trabajo Experimental I	Posgrado
29	21O	Trabajo de Investigación IV	Posgrado
30	21O	Trabajo de Investigación IX	Posgrado
31	21O	Seminario VII	Posgrado
32	21P	Introducción a la Investigación II	Licenciatura
33	21P	Trabajo de Investigación III	Posgrado
34	21P	Trabajo de Investigación VIII	Posgrado
35	21P	Trabajo de Redacción de Tesis III	Posgrado
36	21I	Introducción a la Investigación II	Licenciatura
37	21I	Trabajo de Investigación VII	Posgrado
38	21I	Trabajo de Redacción de Tesis II	Posgrado
39	21I	Trabajo de Investigación II	Posgrado
40	21I	Seminario III	Posgrado
41	21I	Trabajo Experimental III	Posgrado
42	21I	Análisis de Resultados y Escritura de Tesis	Posgrado
43	20O	Introducción a la Investigación II	Licenciatura
44	20O	Trabajo de Investigación I	Posgrado
45	20O	Seminario II	Posgrado
46	20O	Trabajo Experimental II	Posgrado
47	20O	Temas Selectos de Biología de la Reproducción II	Posgrado
48	20O	Seminario VI	Posgrado
49	20O	Trabajo de Investigación VI	Posgrado
50	20O	Trabajo de Redacción de Tesis I	Posgrado
51	20P	Seminario I	Posgrado
52	20P	Trabajo Experimental I	Posgrado
53	20P	Seminario III	Posgrado
54	20P	Seminario III	Posgrado
55	20P	Trabajo Experimental III	Posgrado
56	20P	Trabajo Experimental III	Posgrado
57	20P	Análisis de Resultados y Escritura de Tesis	Posgrado
58	20P	Análisis de Resultados y Escritura de Tesis	Posgrado
59	20P	Seminario V	Posgrado
60	20P	Trabajo de Investigación V	Posgrado

Information provided by the Dirección de Sistemas Escolares

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